National Institutes Of Health Tender

Federal Business Opportunities (fbo) sources Sought Notice solicitation Number: 75n95025q00125 2. Title: Brand-name Or Equal, Acquisition Of Agilent Bioanalyzer 5200 Fragment Analyzer System For Etb Group At Ncats. 3. Classification Code: 6640 4. Naics Code: 334516 – Analytical Laboratory Instrument Manufacturing Dollars Or Number Of Employees: 1,000 Employees description: the Purpose Of This Requisition Is To Procure Brand Name Or Equal, Acquisition Of Bioanalyzer 5200 Fragment Analyzer System For Etb Group At Ncats. The Item Includes The Agilent Bioanalyzer 5200 Fragment Analyzer System, Computer And Monitor, Controller And Analysis Software, Capillary Array, And Installation/familiarization Services.for Advancing Translational Sciences (ncats) background: the National Institutes Of Health (nih) Is The Nation’s Leading Medical Research Agency And The Primary Federal Agency Whose Mission Is To Seek Fundamental Knowledge About The Nature And Behavior Of Living Systems And The Application Of That Knowledge To Enhance Health, Lengthen Life, And Reduce Illness And Disability, Conducting, Supporting And Making Medical Discoveries That Improve People’s Health And Save Lives. the National Center For Advancing Translational Sciences (ncats) Is A Part Of The National Institutes Of Health (nih), Whose Mission It Is To Catalyze The Generation Of Innovative Methods And Technologies That Will Enhance The Development, Testing And Implementation Of Diagnostics And Therapeutics Across A Wide Range Of Human Diseases And Conditions. the Bioanalyzer 5200 Is A Highly Validated Piece Of Equipment For Nucleic Acid Quantification And Characterization, Which Is Important Step In Studies That Intersect With Next-generation Sequencing Approaches. The Fragment Analyzer System Is A Multiplexed Capillary Electrophoresis (ce) Instrument For Performing Automated, High Throughput Separation And Quantification Of Double Stranded Nucleic Acids (dna And/or Rna). Separation Is Achieved By Applying An Electric Field Through A Narrow Bore (50 µm I.d.) Fused Silica Capillary Array Filled With Various Conductive Gel Matrices Designed To Sieve Dna/rna Molecules Of A Specific Size Range. When A High Voltage Is Applied To The Capillary Array, Injected Dna/rna Migrates Through The Gel Matrix As A Function Of Length Or Size, With Smaller Sized Fragments Eluting Faster Than Larger Sized Fragments. At A Point Toward The Far End Of The Capillary Array, Detection Of The Separated Dna/rna Is Achieved By Fluorescence Of A Sensitive Intercalating Dye Present In The Separation Gel Matrix, Which Fluoresces When Bound To Double Stranded Dna Or Rna Molecules. The Fragment Analyzer System Utilizes A High Intensity Light Emitting Diode (led) Excitation Light Source That Is Focused Across The Capillary Array Detection Window And Imaged Onto A Sensitive, Two-dimensional Charge-coupled Device (ccd) Detector. By Monitoring The Relative Fluorescence Unit (rfu) Intensity As A Function Of Time During The Ce Separation, Digital Electropherograms Representative Of The Dna/rna Content Of 12-, 48-, Or 96-samples Are Collected In A Single Experimental Run. purpose And Objectives: brand Name Or Equal, Acquisition Of Agilent Bioanalyzer 5200 Fragment Analyzer System For Etb Group At Ncats. The Item Includes The Bioanalyzer 5200 Fragment Analyzer System, Computer And Monitor, Controller And Analysis Software, Capillary Array, And Installation/familiarization Services. The Bioanalyzer 5200 Fragement Analyzer Can Characterize Nucleic Acids And Sequencing Libraries. The Agilent 5200 Is A Mid-throughput, Electrophoresis Machine For The Analysis Of Dna & Rna. The System Utilizes A Plate-based, Capillary System With A Self-loading Electrophoretic Gel, To Analyze As Little As 50 Pg/ul Of Rna Or 300 Pg/ul Of Dna. The 5200 Is Able To Run Up To 288 Samples Without Manual Intervention From Multiwell Plates And Has Improved Sensitivity And Resolution Over The Bioanalyzer 2100. project Requirements: one (1x) Bioanalyzer 5200 Fragment Analyzer System As Listed In This Documentation. salient Characteristics capillary-based, Automated, High Throughput Separation And Quantification Of Double Stranded Nucleic Acids (dna And/or Rna), With Generation Of Digital Electropherograms For Quantitation Of Nucleic Acid Size (bp) And Concentration. anticipated Period Of Performance: anticipated To Be Delivered Approximately 30 Days Aro place Of Delivery: the Place Of Delivery Shall Be: 9800 Medical Center Dr Bldg B Rockville, Md 20850 other Important Considerations: Independently And Not As An Agent Of The Government, The Contractor Shall Furnish All The Necessary Services, Qualified Personnel, Material, Equipment, And Facilities, Not Otherwise Provided By The Government As Needed To Perform The Work Mentioned Above. capability Statement /information Sought. Respondents Must Provide Clear And Convincing Documentation Of Their Capability Of Providing The Services Specified In This Notice. Also, Information Must Be Provided In Sufficient Details Of The Respondents’ (a) Staff Expertise, Including Their Availability, Experience, Formal And Other Training; (b) Current In-house Capability To Perform The Work; (c) Prior Completed Projects Of Similar Nature; (d) Corporate Experience And Other Management Capability; And (e) Examples Of Prior Completed Government Contracts, References, And Other Related Information. the Respondent Must Also Provide Their Duns Number, Organization Name, Address, Point Of Contact, And Size And Type Of Business (e.g., 8(a), Hubzone, Etc., Pursuant To The Applicable Naics Code And Any Other Information That May Be Helpful In Developing Or Finalizing The Acquisition Requirements. one (1) Copy Of The Response Is Required And Must Be In Microsoft Word Or Adobe Pdf Format Using 11-point Or 12-point Font, 8-1/2” X 11” Paper Size, With 1” Top, Bottom, Left And Right Margins, And With Single Or Double Spacing. the Information Submitted Must Be In And Outline Format That Addresses Each Of The Elements Of The Project Requirement And In The Capability Statement /information Sought Paragraphs Stated Herein. A Cover Page And An Executive Summary May Be Included But Is Not Required. the Response Is Limited To Ten (10) Page Limit. The 10-page Limit Does Not Include The Cover Page, Executive Summary, Or References, If Requested. the Response Must Include The Respondents’ Technical And Administrative Points Of Contact, Including Names, Titles, Addresses, Telephone And Fax Numbers, And E-mail Addresses. all Responses To This Notice Must Be Submitted Electronically To The Contract Specialist And Contracting Officer. Facsimile Responses Are Not Accepted. the Response Must Be Submitted To Giuliana Faller, Contract Specialist At E-mail Address Giuliana.faller@nih.gov. the Response Must Be Received On Or Before January 27, 2025, At 9 Am Eastern Time. “disclaimer And Important Notes: This Notice Does Not Obligate The Government To Award A Contract Or Otherwise Pay For The Information Provided In Response. The Government Reserves The Right To Use Information Provided By Respondents For Any Purpose Deemed Necessary And Legally Appropriate. Any Organization Responding To This Notice Should Ensure That Its Response Is Complete And Sufficiently Detailed To Allow The Government To Determine The Organization’s Qualifications To Perform The Work. respondents Are Advised That The Government Is Under No Obligation To Acknowledge Receipt Of The Information Received Or Provide Feedback To Respondents With Respect To Any Information Submitted. After A Review Of The Responses Received, A Presolicitation Synopsis And Solicitation May Be Published In Federal Business Opportunities. However, Responses To This Notice Will Not Be Considered Adequate Responses To A Solicitation. confidentiality: No Proprietary, Classified, Confidential, Or Sensitive Information Should Be Included In Your Response. The Government Reserves The Right To Use Any Non-proprietary Technical Information In Any Resultant Solicitation(s).”