National Institutes Of Health Tender

This Is A Sources Sought Notice. This Is Not A Solicitation For Proposals, Proposal Abstracts, Or Quotations. The Purpose Of This Notice Is To Obtain Information Regarding The Availability And Capability Of All Qualified Sources To Perform A Potential Requirement. this Notice Is Issued To Help Determine The Availability Of Qualified Companies Technically Capable Of Meeting The Government Requirement And To Determine The Method Of Acquisition, And Availability Of Domestic Sources Manufactured In The United States In Sufficient And Reasonably Available Commercial Quantities And Of A Satisfactory Quality. It Is Not To Be Construed As A Commitment By The Government To Issue A Solicitation Or Ultimately Award A Contract. Responses Will Not Be Considered As Proposals Or Quotes. No Award Will Be Made As A Result Of This Notice. The Government Will Not Be Responsible For Any Costs Incurred By The Respondents To This Notice. This Notice Is Strictly For Research And Information Purposes Only. for Equipment/supply Requirements, Responses Must Include: (1) The Place Of Manufacturer (i.e. Address If Supply/equipment Is A Domestic End Product And Include Country Of Manufacture), As Well As (2) The Size Status Of The Manufacturer Under The Applicable Naics Code (i.e. Address Non-manufacturer Rule). background: The Ninds Mission Is To Seek Fundamental Knowledge About The Brain And Nervous System And To Use That Knowledge To Reduce The Burden Of Neurological Disease For All People. research In The Ninds Neurovascular Research Unit Focuses On Different Neurovascular Coupling Mechanisms In Control Of The Blood Flow In The Brain. This Unit Also Examines Functional Deficits In Molecular Mechanisms In The Small Vessel Diseases Of The Brain And Vascular Cognitive Impairment & Dementia (vcid) Including Stroke And Alzheimer’s Disease. We Rely On Functional Imaging Approaches (in-vivo And Ex-vivo) And Electrophysiology To Answer Scientific Questions. to Study The Signaling Properties Of Cells That Comprise The Neurovascular System, This Laboratory Uses Patch Clamp Electrophysiology, Which Allows Its Researchers To Perform Precise Measurements Of Ion Channel Activities In Different Vascular Cells. To Record The Activity Associated With Individual Ion Channels, There Is A Need For High-precision Digitizers Such As The Molecular Devices Digidata 1550b1 Low Noise Data Acquisition System (part # Digidata 1550b1 And Pclamp 11 Standard) For Collecting Data Through The Acquisition Software Pclamp11, Which Will Allow The Laboratory To Accurately Measure Submillivolt Changes In The Membrane Potential Of Cells Associates With Individual Ion Channel Activity. purpose And Objectives: The Purpose Of This Requirement Is To Procure One (1) Molecular Devices Digidata 1550b1 Low Noise Data Acquisition System (part # Digidata 1550b1 And Pclamp 11 Standard) For Ninds. This Digitizer System Is Needed To Continue Its Laboratory’s Ongoing Research On Different Neurovascular Coupling Mechanisms In Control Of The Blood Flow In The Brain. project Requirements: The Significant, Essential Physical, Functional, Performance, Or Material Element(s) That Are The Government’s Minimum Acceptable Standards For An Equivalent Digidata 1550b1 Low Noise Data Acquisition System (part # Digidata 1550b1 And Pclamp 11 Standard) Manufactured By Molecular Devices To Meet The Government’s Objective Are As Follows: an Equivalent Digitizer Ssytem Shall Have: the System Must Be Compatible With Pclamp 11 Software That Is Used For Acquisition Of Electrophysiology. the System Must Be Able To Sample At 500 Khz Per Channel. the System Must Be Able To Digitize A Wide Range Of Input Signals From -10 To +10v. the System Must Have A Humsilencer That Eliminates 50/60 Hz Line-frequency Noise Pattern Associated With High-frequency Line Harmonics. the System Must Be Low-noise Data Acquisition System Plus 4 Channels Humsilencer Adaptive Noise Cancellation. the Digitizer System Shall Be Warranted, And The Contractor Shall Warrant Its Equipment Against Defects In Material, Fabrication, Or Workmanship For A Minimum Of One (1) Year From The Date From The Date Of Installation, Inspection By The Government, And Acceptance. anticipated Period Of Performance Or Delivery: Ninds Has A Need For Delivery Within 180 Days After Receipt Of Order (aro). other Important Considerations: In Case Domestic Sources Are Available And Capable Of Fulfilling The Government’s Need, And A Future Solicitation Is Published, The Government Will Use Evaluation Preferences In Accordance With Far 25. capability Statement /information Sought. small Business Concerns That Believe They Possess The Capabilities To Provide The Required Products Or Services Should Submit Documentation Of Their Ability To Meet Each Of The Project Requirements To The Contracting Officer. The Capability Statement Must Specifically Address Each Of The Project Requirements Separately. Additionally, The Capability Statement Should Include 1) The Total Number Of Employees, 2) The Professional Qualifications Of Personnel As It Relates To The Requirements Outlined, 3) Any Contractor Gsa Schedule Contracts And/or Other Government-wide Acquisition Contracts (gwacs) By Which All Of The Requirements May Be Met, If Applicable, And 4) Any Other Information Considered Relevant To This Program. Small Businesses Must Also Provide Their Company Name, Uei Number, Physical Address, And Point Of Contact Information. interested Small Businesses Are Required To Identify Their Type Of Business, Applicable North American Industry Classification System (naics) Code, And Size Standards In Accordance With The Small Business Administration. The Government Requests That No Proprietary Or Confidential Business Data Be Submitted In A Response To This Notice. However, Responses That Indicate The Information Therein Is Proprietary Will Be Properly Safeguarded For Government Use Only. Capability Statements Must Include The Name And Telephone Number Of A Point Of Contact Having Authority And Knowledge To Discuss Responses With Government Representatives. Capability Statements In Response To This Market Survey That Do Not Provide Sufficient Information For Evaluation Will Be Considered Non-responsive. When Submitting This Information, Please Reference The Solicitation Notice Number. the Respondent Must Also Provide Their Uei Number, Organization Name, Address, Point Of Contact, And Size And Type Of Business (e.g., 8(a), Hubzone, Etc., Pursuant To The Applicable Naics Code And Any Other Information That May Be Helpful In Developing Or Finalizing The Acquisition Requirements. one (1) Copy Of The Response Is Required And Must Be In Microsoft Word Or Adobe Pdf Format Using 11-point Or 12-point Font, 8-1/2” X 11” Paper Size, With 1” Top, Bottom, Left And Right Margins, And With Single Or Double Spacing. the Information Submitted Must Be In And Outline Format That Addresses Each Of The Elements Of The Project Requirement And In The Capability Statement /information Sought Paragraphs Stated Herein. A Cover Page And An Executive Summary May Be Included But Is Not Required. the Response Is Limited To Ten (10) Page Limit. The 10-page Limit Does Not Include The Cover Page, Executive Summary, Or References, If Requested. the Response Must Include The Respondents’ Technical And Administrative Points Of Contact, Including Names, Titles, Addresses, Telephone And Fax Numbers, And E-mail Addresses. all Responses To This Notice Must Be Submitted Electronically To The Contract Specialist And Contracting Officer. Facsimile Responses Are Not Accepted. the Response Must Be Submitted Via Email To The Contracting Officer, Rieka Plugge (rieka.plugge@nih.gov). the Response Must Be Received On Or Before 7/29/2024, 10:00 A.m., Eastern Time. “disclaimer And Important Notes: This Notice Does Not Obligate The Government To Award A Contract Or Otherwise Pay For The Information Provided In Response. The Government Reserves The Right To Use Information Provided By Respondents For Any Purpose Deemed Necessary And Legally Appropriate. Any Organization Responding To This Notice Should Ensure That Its Response Is Complete And Sufficiently Detailed To Allow The Government To Determine The Organization’s Qualifications To Perform The Work. respondents Are Advised That The Government Is Under No Obligation To Acknowledge Receipt Of The Information Received Or Provide Feedback To Respondents With Respect To Any Information Submitted. After A Review Of The Responses Received, A Presolicitation Synopsis And Solicitation May Be Published In Federal Business Opportunities. However, Responses To This Notice Will Not Be Considered Adequate Responses To A Solicitation. confidentiality: No Proprietary, Classified, Confidential, Or Sensitive Information Should Be Included In Your Response. The Government Reserves The Right To Use Any Non-proprietary Technical Information In Any Resultant Solicitation(s).”