National Institutes Of Health Tender

This Notice Is A Combined Synopsis/solicitation For Commercial Items Using Simplified Acquisition Procedures. This Acquisition Will Be Made In Accordance With The Format In Federal Acquisition Regulation (far) Subpart 12.6 “streamlined Procedures For Evaluation And Solicitation For Commercial Items,” As Applicable, And As Supplemented With Additional Information Included In This Notice. This Announcement Constitutes The Only Solicitation (a Written Solicitation Will Not Be Issued) And Quotes Are Being Requested. The Solicitation Number Is Rfq-niaid-24-2229582 And The Solicitation Is Issued As A Request For Quotes (rfq). this Acquisition Will Be Processed Under Far Part 13 Simplified Acquisition Procedures (sap). The Solicitation Documents And Incorporated Provisions And Clauses Are Those In Effect Through Federal Acquisition Circular (fac) 2024-04 May 22, 2024. the North American Industry Classification System (naics) Code For This Procurement Is 334516, Analytical Laboratory Instrument Manufacturing, With A Size Standard Of 1000 Employees. The Requirement Is Being Competed With A Brand Name Restriction, And Without A Small Business Set-aside. the National Institute Of Allergy And Infectious Diseases (niaid) Conducts And Supports Basic And Applied Research To Better Understand, Treat, And Ultimately Prevent Infectious, Immunologic, And Allergic Diseases. For More Than 50 Years, Niaid Research Has Led To New Therapies, Vaccines, Diagnostic Tests, And Other Technologies That Have Improved The Health Of Millions Of People In The United States And Around The World. the National Institute Of Allergy And Infectious Diseases (niaid), National Institute Of Allergy And Infectious Diseases (niaid), Division Of Intramural Research (dir), Laboratory Of Immunoregulation (lir), Focuses Its Research Efforts On The Elucidation Of Cellular And Molecular Mechanisms That Regulate The Human Immune Response In Health And Disease, Specifically, How Immune Cells Respond To Pathogens And Other Antigens In Health And Disease. Since 2017, It Has Formed Partnerships With Other Niaid Labs Is To Investigate How Immune Cells Respond To Different Human Pathogens, Including Hiv And Sars-cov-2. The Objectives Of These Efforts Include Investigating Antigen-specific B-cell Responses Using Single-cell Analyses, To Better Understand Of How B Cells Respond To Different Pathogens, Including Hiv. Among The Ongoing Efforts Are Those Involving Analyses Of B-cell Function In Various Cross-sectional And Longitudinal Settings Of Hiv Disease. In Addition, A Second Objective Involves Understanding How B Cells, T Cells And Other Immune Cells Of People Living With Hiv Are Affected By Residual Viral Replication And How This Affects The Ability To Mount An Effective Immune Response Against Hiv And Other Pathogens. The Samples Will Consist Of Human Peripheral Blood Cells Collected And Stored Under Our Longstanding Observational Clinical Research Protocol, 02-i-0202, As Well As Interventional Studies Registered Under Clinicaltrials.gov Id Nct03225118, Nct01859325, And Nct05612178. The Results Of This Project Will Be Compared To Our Previously Published Data On Sars-cov-2 Using This Platform And Thus It Is Imperative That We Use The Same Standardized Approach For The Proposed Project. project Description: lir Has A Current Requirement For Supplies That Consist Of 10x Genomics Reagent Kits And Instrumentation To Perform Cdna Barcoding And Library Construction. The Main Reagent Components Needed Are Chromium Single Cell 5’ Reagent Kits That Include A Gel Bead Emulsion (gem) Single Cell 5’ Library And Gel Bead Kit, Accompanying Library Construction And Barcoding Kits, As Well As B Cell And T Cell Vdj (bcr & Tcr) Enrichment Kits And Two Different Single Index Kits. description Of Need: visium Cytassist, Product Code 1000441, Qty 1 visium Cytassist Reagent Accessory Kit, Product Code 1000499, Qty 1 chromium Next Gem Single Cell Multiome Atac + Gene Expression Reagent Bundle,16 Rxns, Product Code 1000283, Qty 3 single Index Kit N Set A, 96 Rxn, Product Code 1000212, Qty 1 chromium Next Gem Single Cell 5' Kit V2, 16 Rxns, Product Code 1000263, Qty 1 5' Feature Barcode Kit, 16 Rxns, Product Code 1000541, Qty 3 visium Hd, Mouse Transcriptome, 6.5 Mm, 16 Rxns, Product Code 1000674, Qty 1 dual Index Kit Ts Set A, 96 Rxn, Product Code 1000251, Qty 1 chromium Next Gem Single Cell 3' Ht Kit V3.1, 8 Rxns, Product Code 1000370, Qty 1 3' Feature Barcode Kit, 16 Rxns, Product Code 1000262, Qty 1 chromium Gem-x Single Cell 5' Kit V3, 4 Rxns, Product Code 1000695, Qty 2 chromium Gem-x Single Cell 5 Feature Barcode Kit V3, 16 Rxns, Product Code1000703, Qty 1 chromium Single Cell Mouse Tcr Amplification Kit, 16 Rxns, Product Code 1000254, Qty 1 chromium Gem-x Single Cell 5' Chip Kit V3, 4 Chips, Product Code 1000698, Qty 1 shipping And Handling, Qty 1 delivery: 45 Days Aro place Of Performance: Nih, Building 40, 40 Convent Drive, Bethesda, Md 20892, United States. Fob: Destination the Government Intends To Award A Firm Fixed Price Purchase Order To The Responsible Contractor As A Result Of This Rfq That Will Include The Terms And Conditions Set Forth Herein. The Award Will Be Based On The Following: Technical Capability To Meet The Requirements And Price. by Submitting A Quote In Response To This Solicitation, Vendor Is Accepting The Following Terms And Conditions: the Following Far Provisions Apply To This Acquisition: far 52.212-1 Instructions To Offerors Commercial Items (sep 2023) far 52.212-3 Offerors Representations And Certifications - Commercial Items (may 2024) far 52.204-7 System For Award Management (oct 2018) (offerors Must Complete Annual Representations And Certifications On-line At Http://www.sam.gov/ In Accordance With Far 52.212-3 Offerors Representations And Certifications- Commercial Items (please Ensure Far 52.209-2 -- Prohibition On Contracting With Inverted Domestic Corporations--representation. (nov 2015) Is Updated In Your Sam Record) far 52.203-18 Prohibition On Contracting With Entities That Require Certain Internal Confidentiality Agreements – Representation (jan 2017) far 52.204–26 Covered Telecommunications Equipment Or Services-representation (oct 2020) *** Must Complete Representation If Attached To This Solicitation- See Attachment 52.204-26 the Following Far Contract Clauses Apply To This Acquisition: far 52-212-4 Contract Terms And Conditions Commercial Items (nov 2023) far 52-212.5 Contract Terms And Conditions Required To Implement Statutes Or Executive Orders Commercial Items (may 2024) *the Applicable Subparagraphs Of Far52.212-5 Are Included In The Attachment To This Posting. far 52.232-40 Providing Accelerated Payments To Small Business Subcontractors (mar 2023) far 52.204-13 System For Award Management Maintenance (oct 2018) far 52.204-25 Prohibition On Contracting For Certain Telecommunications And Video Surveillance Services Or Equipment (nov 2021) hhsar 352.222-70, Contractor Cooperation In Equal Employment Opportunity Investigations (dec 2015) 52.252-2 -- Clauses Incorporated By Reference. (feb 1998) this Contract Incorporates One Or More Clauses By Reference, With The Same Force And Effect As If They Were Given In Full Text. Upon Request, The Contracting Officer Will Make Their Full Text Available. Also, The Full Text Of A Clause May Be Accessed Electronically At This Address: Http://farsite.hill.af.mil/vffara.htm by Submission Of An Offer, The Offeror Acknowledges The Requirement That A Prospective Awardee Shall Be Registered In The System For Award Management (sam) Database Prior To Award, During Performance, And Through Final Payment Of Any Contract, Basic Agreement, Basic Ordering Agreement, Or Blanket Purchasing Agreement Resulting From This Solicitation (www.sam.gov). copies Of The Above-referenced Provisions And Clauses Are Available From Http://www.acquisition.gov/far/loadmainre.html & Http: //www.hhs.gov/regulation/index.html Or, Upon Request, Either By Telephone Or Fax. submission Shall Be Received Not Later Than 7/25/2024 @ 4:00 Pm Est all Quotations And Required Documents Must Be Submitted Via The Niaid Electronic Simplified Acquisition Submission System (esass) Website At Https://esass.nih.gov. All Vendors Must Register In The Esass System To Submit A Quotation. Instructions On How To Register / Submit Quotes Are Included On The Website. Late Submissions Shall Be Treated In Accordance With The Solicitation Provision At Far 52.212-1(f). All Responsible Sources May Submit An Offer That Will Be Considered By This Agency.