Data Center Tenders

Purchaser Name: Awarding Office For The Municipal Data Center In The Lower Rhine Region | To the call for proposals 'apple 2024'

Details: Description Supply Of Rack Mounted Server To Be Used For Iskolar And Other Is Project (rebid) Specifications Per Node: Processor 2x Intel(r) Xeon(r) Gold 6544y Or Better/equivalent* Core And Thread Count Minimum Of 16 Cores, 32 Threads Ram Minimum Of 512gb (in 64gb Rdimm) Os Disk Minimum Of 2x 240gb 2.5” Sata Ssd Cache Disk Minimum Of 2x 3tb 2.5” Sata Ssd Storage Disk Minimum Of 6x 10tb 3.5” Sas Hdd 7200 Rpm Storage Controller 1x Sas/sata Controller With Raid 0, 1, 5, 6, 10, 50 And 60 Power Supplies Hot Plug Power Supplies With Full Redundancy Option Drive Bays 12 Front Hot-swap 2.5”/3.5” Nvme/sas/sata Drive Bays Form Factor Rackmount 2u Security Tpm V2.0 Nic Card At Least 1x 4-port 10gbe Sfp+ Onboard Lan 2-port 10gbe Rj45 Ports (minimum) 2 X Usb 3.0 1 X Vga Or Hdmi Other Inclusions: • At Least 8x Sfp+ Transceiver Modules For Short Range Fiber Cables (up To 300m) • Raid Setup Should Be Handled By The Supplier • At Least 7x Lc-lc Multi-mode Fiber Cables (3 Meters) • Supply, Installation, Commissioning, And Management Training • Keyboard, Mouse, Monitor(at Least 20”) With Kvm Warranty 3- Year Software Warranty 5-year Manufacturer’s Warranty For Hardware With Accessories To Operate Fully *equivalent Is Defined As A Model From Another Manufacturer That Is Within 5% Of Benchmark Scores As Determined By The Benchmark Tool Chosen By The Ims Hci Server Software Features: Technology Hyperconverged Infrastructure (hci) Server Virtualization – Virtualizes Cpu, Memory, And I/o Devices Through A Virtual Machine Monitor Vm Resource Hot Add Must Support Thot Addition To The Cpu And Memory Of The Virtual Machine And Hot Plug To The Interface And Disk Of The Virtual Machine Dynamic Thermal Addition Must Be Able To Dynamically Expand The Virtual Machine's Cpu And Memory Resources, Ensuring Business Continuity. Virtual Machine High Availability (ha) When The Node Where The Virtual Machine Is Located Has An Accident (node Power Outage, Interface Drop, Etc.), A Node With Sufficient Resources Will Be Selected To Restart The Virtual Machine, Which Significantly Reduces The Service Interruption Time. Virtual Machine Fast Pull Up Must Have A Quick Pull-up Function Can Immediately Create And Start The Virtual Machine When It Needs To Be Restored. The Process Can Be Completed In 3 Minutes, And The Performance Will Climb To The Normal Within 15 Minutes, Which Can Quickly Help Users Restore Business Operation And Ensure Business Continuity. Rto <= 15 Minutes. Sub Health Node Monitoring Must Be Able To Monitor Whether The System Disk And Memory Of The Node In The Cluster Are In The Sub-health State, Give Treatment Opinions To The Sub-health Node And Reduce The Priority Of The Sub-health Node In The Process Of Virtual Machine Startup (or Ha) Node Selection. Supports Processing Five Sub-health States: Memory Ce And Ue Errors On The Node, Read-only System Disk, Insufficient Ssd Lifetime, And Bad Channel On Hdd. Virtual Machine Data Protection Must Be Able To Record Every Io Of The Business System To The Disk In The Virtual Machine, Restore The Virtual Machine To The State At Any Time, Or Directly View And Download File At A Certain Time. It Is Of Great Value For File Deletion, Virus, System Crash, Data Damage And Other Faults, So That The Rpo Is Close To 0. Storage Virtualization Data Striping Must Have Striping Technology To Maximize I/o Concurrency Multi Replica Mechanism Supports 2 Replica And 3 Replica – Must Be Able To Support 2 Replica And 3 Replica Policies. Storage Snapshot Must Be Able To Support The Storage Snapshot Function. When Creating A Virtual Machine Snapshot, The System Will Set The Source Virtual Disk As Read-only And Generate A Corresponding Number Of New Disk Files (i.e., Snapshot Space). After The Snapshot Is Created, All New Data And Modifications To The Source Data Of The Virtual Machine Will Be Written To The Newly Generated Snapshot Space. The Corresponding Relationship Between The Logical Address Of The Source Virtual Disk And The Snapshot Space Will Be Written In The Mapping Table. Virtual Machine Cloning Must Have An On The Basis Of Full Cloning Of Virtual Machines. It Should Support Both Link Cloning And Fast Full Cloning Of Virtual Machines. Host Multi Volume Must Support The Establishment Of Multiple Storage Sub Volumes By Selecting Different Nodes In A Cluster. Data Rebuilding Must Have A Data Rebuilding Function. After A Component (disk Or Node) Fails, It Will Take Another Copy Of The Data On The Failed Component As The Repair Source, Rebuild A New Copy On The Target Component In The Unit Of Fragmentation, Restore The Integrity, And Realize System Self-heal. Virtual Iscsi Technology Must Have Virtual Iscsi Technology That Allows The Creation Of A Virtual Iscsi Hard Disk And Supports Access From A Virtual Storage Communication Network Port. Disk Sub-health Scanning And Repair Must Be Able To Find Hidden Bad Sectors In Time Through The Active Scanning Function Of Bad Sectors To Avoid The Data Being In The Single-copy State For A Long Time. Capacity Prediction Must Be Able To Dynamically Predict The Capacity Growth Trend In The Next 90 Days According To The Capacity Usage Of Customer Clusters. In The Capacity Prediction Interface, The User Can Switch And View The Raw Capacity, Actual Used Capacity, And Dynamic Prediction Curve Of Different Virtual Datastore. Network Virtualization Distributed Virtual Firewall Must Have A Distributed Firewall Is Equivalent To Placing A Firewall At The Exit And Entrance Of Each Virtual Machine. As Long As A Policy Is Configured, It Can Dynamically Adjust In The Background No Matter How The Topology Changes, Where The Virtual Machine Runs, Or Change Of The Ip. Virtualization Of Network Functions Must Be Able To Separate Network Functions From Proprietary Hardware Devices And Implement These Functions As Software To Support The Infrastructure With Complete Integration Of Virtualization Components. Simple Deployment Must Be Able To Deploy The Infrastructure With “what You Draw Is What You Get” Topology. Terms Of Reference 1. Background Of The Item Being Procured 1.1 General Overview Of The Procurement Project The Information Management Service (ims) Of The University Of The Philippines Manila (upm) Is Acquiring High Performance Rack Mounted Servers To Meet The Universities Growing Computing Needs And Support New Critical Applications Such As Iskolar And Other New Information Systems Developed By The Ims Team 1.2 Brief Description Of The Item Being Procured The Item Being Procured Is Based On The Intended User And Its Needs. The New Rack Mounted Servers Should Be High-performance, Scalable, Reliable And Secure To Meet The Universities. The Goal Is To Support The Production Of The New Information Systems While Improving Our Digital Infrastructure. 1.3 Abc Of The Project And Fund Source 1.3.1 The Abc Of The Project Is Six Million Pesos (php6,000,000.00) 1.3.2 The Fund Source Is The Up-manila Funds 1.3.3 Detailed Financial Breakdown Item Qty Unit Cost Total Price Rack Mounted Servers 2 Un Php 3,000,000.00 Php 6,000,000.00 Total Php 6,000,000.00 2. Mode Of Procurement 2.1 The Mode Of Procurement Will Be Competitive Bidding Procurement, In Accordance With The Provisions Of The Government Procurement Reform Act (ra 9184). 3. Nature Of Procurement 3.1 Goods And Services, Including Hardware, Software, And Training Modules. 4. Scope Of Work 4.1 The Selected Vendor Shall Be Responsible For The Supply And Installation Of 2 Units Of Rack Mounted Servers. 4.2 The Vendor Shall Provide The Following Documents With The Delivery: 4.2.1.1 User Manuals For Each Unit. 4.2.1.2 Warranty Certificates 4.2.1.3 Installation Guide 4.3 The Selected Vendor Should Provide Rack Mounted Servers That Meet Or Exceed The Minimum Technical Requirements. (all Specifications And Details Are Attached Together With This Document) 4.3.1 Warranty And Support 4.3.1.1 The Vendor Must Provide A Minimum Of 5 Years Of Warranty For The Hardware, And 3 Years For The Hci Software. 4.3.1.2 Warranty Includes Parts, Labor, 24/7 Technical Support And On-site Support For Any Issues Or Failures. 4.3.1.3 Software License And Update, License Upgrade Should Be Included In The 3-year Warranty For The Hci Software. 4.3.1.4 The Supplier Must Provide After-sales Technical Support. 4.3.1.5 The Vendor Must Ensure The Availability Of Replacement Parts During The Warranty Period 5. Deployment 5.1 The Rack Mounted Server Should Be Deployed And Installed In The Ims Data Center. 6. Terms And Conditions 6.1 Indicate Brand, Model, And Country Of Origin. 6.2 Notarized Certificate That The Product Is Brand New, Not Reconditioned/refurbished Including Parts And Accessories. 6.3 Delivery And Installation Should Be Done Within 90 Calendar Days Commencing On The Date Of Receipt Of Purchase Order And Notice To Proceed. Notification By Email And Acknowledged By The Supplier Constitutes The Date Of Acceptance. The Equipment Must Be Delivered Ready To Use. Cables, Connectors, Adapters, And Accessories Even Not Specified But Are Essential For The Unit To Function Must Be Provided Free By The Winning Bidder. 6.4 Certification From At Least Three (3) Government And/or Private Agencies Within Metro Manila Or The Philippines That They Have Been Supplied With The Same Brand Being Offered. Two (2) Of Which Must Implement The Same Hci Solution To A School, University, Or Government Agency In The Philippines. 6.5 Undertaking To Provide Product Orientation, Operations Training, And Troubleshooting Training To At Least Three (3) It Personnel Which Should Include The Following: A. Administration B. Troubleshooting C. Hci Architecture Implementation D. Installation 6.6 The Warranty Should Be At Least 5 Years For Service And 5 Years For Parts For The 2 Rack Mounted Servers, And 3 Years For The Hci Software. 6.7 The Warranty Period Shall Commence From The Date Of Acceptance By The End-user, Testing And Commissioning. 6.8 Provide Regular Quarterly Preventive Maintenance During The Warranty Period. 6.9 A Notarized Certification From The Manufacturer That The Contractor Is An Authorized Distributor Of The Equipment. 6.10 Notarized Certification From The Manufacturer And Local Distributor That In The Event Of A Change Of Local Distributor, Preventive Maintenance, Warranty, And Services Agreed Here Upon Will Be Honored By The Principal Manufacturer. 6.11 Notarized Certification That The Local Distributor And The Manufacturer Have Been In Business Relationship Of Providing That Said Equipment For At Least Five (5) Years. 6.12 Notarized Certification Accompanied With Proof That The Contractor Is In The Business Of Supplying The Unit/item For The Last Five (5) Years. 6.13 Certification That The Manufacturer Of The Hci Software Is Capability Maturity Model Integration Level 5 (cmmi L5) Certified To Ensure The Maturity Of The Hci Solution Technology. 6.14 Certification That The Bidder Has At Least Three (3) Specialists/technical Engineers With Certification From The Manufacturer As An Hci Implementor. 6.15 Guarantee Letters Or Certificate From The Manufacturer And Local Distributor To Ensure The Availability Of Parts, Supplies And Accessories And Will Not Be Discontinued For The Next Five (5) Years. 6.16 Provide Separate Quotations For Maintenance, Repair, And Replacement Of Parts After Warranty Period. 6.17 Provide Operator’s & Service Manual (in English Language) Upon Delivery. 6.18 The Bidder Must Submit Certification That They Have A Capability For Corrective And Preventive Maintenance Of The Unit Or Have A Service Center Within Metro Manila 6.19 Must Guarantee That The Diagnostic Technician Will Be Able To Assess The Unit Within 24 Hours Of Notification (if Applicable). 6.20 Automatic Provision Of A Functioning Service Unit (same Model Or Higher) In Case Repair Of More Than 3 Days/pull Out Of The Purchased Unit During The Warranty Period. 6.21 The Winning Bidder Will Be Responsible For All Fees For Performance Testing, Delivery, Installation And Commissioning The Unit (if Applicable). 6.22 Specific Place Of Delivery: 2nd Flr. Ims Office Information Technology Center (itc), Joaquin Gonzalez Compound, Up Manila, Padre Faura St., Ermita, Manila. Metro Manila~manila - Ermita - Barangay 669. In Case Of Large Equipment, The End-user Should Issue A Certification, Noted By The Dean/director, That The Identified Space Is Available, 6.23 Terms Of Payment: Payment Must Only Be Made After The Appropriate Inspection And Acceptance Procedures, As Mandated By Existing Government Rules And Regulations, Have Been Complied With By The Procuring Entity. 7. Testing And Acceptance 7.1 The Vendor Must Ensure That All Rack Mounted Servers Are Fully Functional And Ready For Use Upon Delivery. 7.2 Inspection By The Ims And Spmo To Verify The Functionality, Compliance With Specifications, Quantity And Overall Quality Of The Rack Mounted Servers 7.3 Rack Mounted Servers Will Be Considered Accepted Upon Successful Completion Of Testing And Verification 7.4 The Vendor Must Comply With The Indicated Specifications And Scope Of Work Written In This Document 8. Other Requirements 8.1 Vendor Must Meet The Following Eligibility Criteria And Have Proven Experience In Supply And Installation Of Rack Mounted Servers 8.2 Eligibility Requirements: 8.2.1 Valid Mayor's Permit 8.2.2 Valid Philgeps Registration 8.2.3 Income/business Tax Return 8.2.4 Omnibus Sworn Statement

Details: The National Institute Of Diabetes And Digestive And Kidney Diseases (niddk) Seeks Industry Partners For Clinical Research Collaborations On Therapeutics, Diagnostics Or Devices For Childhood Cholestatic Liver Diseases the National Institute Of Diabetes And Digestive And Kidney Diseases (niddk) Of The National Institutes Of Health (nih) Of The Department Of Health And Human Services (dhhs) Seeks Industry Collaborators To Provide Novel Therapeutic Agents, Diagnostic Markers, Biomarkers And Devices For Use In Nih-sponsored Multi-center Clinical Trials And Ancillary Studies In Patients With Childhood Cholestatic Liver Diseases, Including Biliary Atresia, Alpha-one Antitrypsin Deficiency, Cystic Fibrosis Liver Disease, Alagille Syndrome, Progressive Familial Intrahepatic Cholestasis (pfic), Bile Acid Synthesis Defects, Mitochondrial Respiratory Chain And Fatty Acid Oxidation Defects, Primary Sclerosing Cholangitis, And Idiopathic Neonatal Hepatitis; And The Liver Disease Related Complications Emanating From These Diseases. background: The Childhood Liver Disease Research And Education Network (children) Is A Multi-center Consortium Of 10 Clinical Sites In The United States Plus A Scientific Data Coordinating Center Funded By Niddk To Study Rare Childhood Liver Diseases That Result In Cholestasis, Including Primary Sclerosing Cholangitis, Biliary Atresia, Alpha-one Antitrypsin Deficiency, Cystic Fibrosis Liver Disease, Alagille Syndrome, Progressive Familial Intrahepatic Cholestasis (pfic), Bile Acid Synthesis Defects, Mitochondrial Respiratory Chain And Fatty Acid Oxidation Defects, And Idiopathic Neonatal Hepatitis. Five Ongoing Studies Being Conducted By Children Include: 1) A Prospective Database Of Infants With Cholestasis (probe), A Longitudinal Observational Study Starting In Infancy Which Has Enrolled 890 Infants With Biliary Atresia And 621 With Intrahepatic Cholestasis; 2) Biliary Atresia Study In Infants And Children (basic), A Longitudinal Study Of Children With Biliary Atresia Both Before And After Liver Transplant, Which Has Enrolled Over 1768 Children With Biliary Atresia 3) Longitudinal Study Of Genetic Causes Of Intrahepatic Cholestasis (logic), A Longitudinal Study Of Intrahepatic Cholestasis Diseases, Which Has Enrolled 474 Subjects With Alagille Syndrome, 572 With Alpha-1 Antitrypsin Deficiency Liver Disease, 355 With Pfic And 36 With Bile Acid Defects; 4) Longitudinal Study Of Mitochondrial Hepatopathies (mitohep) With 73 Participants; And 5) Prediction By Ultrasound Of The Risk Of Hepatic Cirrhosis In Cystic Fibrosis (push), A Study Of The Prognostic Value Of Hepatic Ultrasound On The Development Of Liver Fibrosis In Cf, Which Has Enrolled Over 770 Subjects. In Addition, Children Completed A Placebo-controlled Clinical Trial To Determine If Post-operative Corticosteroid Therapy Improves Serum Bilirubin And Survival Without Liver Transplantation In 140 Infants With Biliary Atresia Who Have Undergone The Kasai Surgery ("start"). Ancillary Studies To Evaluate The Natural History, Clinical Outcomes And Quality Of Life, Pathogenesis, Genetics And Genomics, Proteomics, Metabolomics, Lipidomics, Imaging Studies, And Determinants Of Progression And Severity Of These Cholestatic Liver Diseases Present A Variety Of Research Collaboration Opportunities. Children Is Also Interested In Conducting Clinical Trials Of Promising Therapies To Improve Clinical Outcomes For These Cholestatic Liver Diseases. Finally, Improved Diagnostics Or Screening Procedures For Biliary Atresia And Cholestasis In Infants Are Of Great Interest To Children. study Goals: The Overall Goal Of Children Is To Determine The Etiology, Genetics, Pathogenesis, Natural History, Clinical Outcomes, Complications, Predictors Of Outcomes And Optimal Therapy Of The Cholestatic Liver Diseases. Children Studies Have Enrolled And Are Following A Relatively Large And Well Characterized Population Of Children And Young Adults With These Rare Disorders. Children Is Interested In Conducting Research That Will Lead To Improved Clinical Outcomes In Children And Young Adults With These Cholestatic Liver Diseases With Industry Collaborators To: • Evaluate The Natural History, Pathogenesis, Diagnosis, Genetic Factors, Genomics, Proteomics, Metabolomics, Lipidomics, Epigenomics, Imaging Studies, And Determinants Of Progression And Severity Of Biliary Atresia, Alpha-one Antitrypsin Deficiency, Cystic Fibrosis Liver Disease, Alagille Syndrome, Pfic, Bile Acid Synthesis Defects, Mitochondrial Respiratory Chain And Fatty Acid Oxidation Defects, Primary Sclerosing Cholangitis, Or Idiopathic Neonatal Hepatitis. • Explore Use Of Serum Markers For Fibrosis And Serum Markers For Disease Activity To Predict Hepatic Histology Either By Themselves Or In Combination With Other Clinical, Laboratory, Genomic, Proteomic, Metabolomic, And Lipidomic Variables • Explore The Utility Of These Serum Markers As Surrogate Markers Of Therapeutic Response In Study Subjects Participating In Treatment Trials (e.g., Start Study For Biliary Atresia) • Investigate Proprietary Drugs (such As Novel Choleretic Agents, Anti-fibrogenic Agents, Autophagy Inducers, Chloride Channel Inducers, Fat-soluble Vitamin Supplements, Bone Mineral Density Agents, Etc.), Reagents, Or Devices In Controlled Randomized Clinical Trials As Potential Diagnostics Or Therapies For Biliary Atresia, Alpha-one Antitrypsin Deficiency, Cystic Fibrosis Liver Disease, Alagille Syndrome, Pfic, Bile Acid Synthesis Defects, Mitochondrial Respiratory Chain And Fatty Acid Oxidation Defects, Primary Sclerosing Cholangitis, Or Idiopathic Neonatal Hepatitis • Evaluate Novel Newborn Or Infant Screening Techniques Or Devices For Biliary Atresia Or Cholestasis. • Evaluate Noninvasive Imaging Methods For Assessing Fibrosis, Biliary Disease, And Parenchymal Pathology In These Diseases Including But Not Limited To The Use Of Elastography, Nuclear Magnetic Resonance Imaging, And Molecular Imaging. • Evaluate The Use Of Cytokine Assays For Analyses Of Serum/plasma Cytokine Levels As Markers Of Disease Activity And As Surrogate Markers Of Histologic Or Clinical Improvement In Therapeutic Trials capability Statement: Commercial Organizations Interested In Pursuing Clinical Collaborations With Niddk For Childhood Cholestatic Liver Diseases Are Required To Submit A Capability Statement To Niddk. The Capability Statements Submitted In Response To This Announcement Will Be Used To Evaluate And Select Industry Collaborators. The Capability Statement Should Not Exceed 10 (ten) Pages Of Narrative (not Including Appendices) And Should Include The Following Information: 1. A Description Of The Therapeutic, Diagnostic Or Device Proposed To Be Used In The Clinical Research Study. (note: The Proposed Therapeutic Or Device Must Have Been Tested Already In A Phase I Trial In Humans.) 2. The Specific Details Of The Methods To Be Utilized In The Investigation Of The Pharmacologic, Surgical Or Device Intervention In Patients With Biliary Atresia, Alpha-one Antitrypsin Deficiency, Cystic Fibrosis Liver Disease, Alagille Syndrome, Pfic, Bile Acid Synthesis Defects, Mitochondrial Respiratory Chain And Fatty Acid Oxidation Defects, Primary Sclerosing Cholangitis, Or Idiopathic Neonatal Hepatitis, And A Clear Description Of All Important Issues Surrounding The Evaluation Of Disease Progression In These Patients. 3. A Detailed Plan Demonstrating The Ability To Provide Sufficient Quantities Of The Therapeutic, Diagnostic Or Device In A Timely Manner For The Duration Of The Study. 4. A Description Of All Laboratory Tests That Are Needed, Including Assays And Required Amount Of Specimens, To Determine Specific Biomarker Levels Along With Appropriate Methods For Performing Such Tests. 5. A Description Of Other Core Facilities And Interactions With Core Facilities That Are Needed For The Study. 6. Dosing And Pharmacokinetic Data From Human Studies For Any Novel Therapeutics. 7. Adverse Event Profile For The Proposed Therapeutic Or Device. 8. A Description Of The Practices And Procedures That Would Be Used To Assure Patient Privacy And Maintain Confidentiality Of Data Obtained From The Study. 9. (optional) Outcome Measures Of Interest To The Organization. The Specifics Of The Proposed Outcome Measures Should Include But Not Be Limited To Treatment And Evaluation Of Biliary Atresia, Alpha-one Antitrypsin Deficiency, Cystic Fibrosis Liver Disease, Alagille Syndrome, Pfic, Bile Acid Synthesis Defects, Mitochondrial Respiratory Chain And Fatty Acid Oxidation Defects, Primary Sclerosing Cholangitis, Or Idiopathic Neonatal Hepatitis. 10. Any Other Resources The Organization Proposes To Commit To The Collaboration (in Addition To The Proposed Therapeutic, Diagnostic Or Device), Which May Include Any Of The Following: Equipment, Reagents, Supplies, Access To Facilities, Personnel Or Services, And, If Appropriate, Funding (pursuant To A Cooperative Research And Development Agreement (crada) Authorized Under 15 U.s.c. § 3710a), To Help Support The Conduct Of The Clinical Study. 11. Affirmative Statements That The Organization: a. Agrees To Provide A Letter Of Cross Reference To The Drug, Biologic Or Device Master File For The Proposed Therapeutic Or Device, Which Will Be Included With Any Us Fda Filing By The Ind Or Ide Sponsor Of The Children Study; b. Agrees To Have The Proposed Therapeutic, Diagnostic Or Device Used In Children-developed Protocols Which Will Be Conducted By The Children Research Network For Which The Study Data Collection And Analysis Will Be Performed By The Children Scientific And Data Coordinating Center; c. Agrees To Assure Patient Privacy And Will Maintain Confidentiality Of Data Obtained From The Study; d. Agrees To Share All Safety Data From Other Studies Involving The Proposed Therapeutic Or Device As Well As Relevant Efficacy Data From Other Studies (updated Investigator Brochure, Etc) With The Children; e. Understands That Because The Children Network Is Supported By Niddk Funding, The Study Results Will Be Published And Therefore Agrees To The Prompt Publication Of Research Results From The Clinical Study Using The Organization's Proposed Therapeutic, Diagnostic Or Device; And f. Understands That The Clinical Study Will Be Conducted Under An Agreement With Niddk Which Must Adhere To Phs Intellectual Property Policies (see: Http://www.ott.nih.gov/policy/phspat_policy.aspx). submission: Capability Statements Received By Niddk Will Be Considered. Prospective Collaborators May Be Invited To Attend, At Their Own Expense, A Children Steering Committee Meeting To Be Held In The Baltimore-washington, Dc Area To Discuss The Information In Their Capability Statement With The Steering Committee Members. Note:no Funds Will Be Provided By Niddk To Any Organization Selected For This Clinical Research Collaboration Opportunity. submision And Inquiries: Submit Capability Statements To: noo Coordinator, National Institute Of Diabetes And Digestive And Kidney Diseases e-mail: Niddkottdip@niddk.nih.gov for Scientific Inquiries Contact: edward Doo, Md director, Liver Diseases Research Program division Of Digestive Diseases And Nutrition, Niddk 6707 Democracy Blvd., Room 6149 bethesda, Md 20892-5450 telephone: (301) 451-4524 fax: (301) 480-8300 e-mail: Dooe@niddk.nih.gov katrina Loh, Md director, Pediatric Gastrointestinal And Liver Diseases division Of Digestive Diseases And Nutrition, Niddk 6707 Democracy Blvd., Room 6148 bethesda, Md 20892-5450 telephone: (301) 827-1079 fax: (301) 480-8300 e-mail: Katrina.loh@nih.gov for Inquiries Regarding Partnering With Niddk (intellectual Property Matters And Collaboration Agreements) Contact: agnes Rooke, Jd technology Advancement Office niddk, Nih, Hhs telephone: 301-451-6072 e-mail: Agnes.rooke@nih.gov this Notice Of Opportunity Is Also Posted At: Http://techdev.niddk.nih.gov/collabs.shtml.

Details: Request For Information pursuant To Far 15.201(e) - This Is A Request For Information (rfi) Only. This Rfi Is Issued Solely For Information And Planning Purposes – It Does Not Constitute A Request For Proposal (rfp) Or A Promise To Issue An Rfp In The Future. This Request For Information Does Not Commit The Government To Contract For Any Supply Or Service Whatsoever. Further, The Government Is Not At This Time Seeking Proposals And Will Not Accept Unsolicited Proposals. Responders Are Advised That The U.s. Government Will Not Pay For Any Information Or Administrative Costs Incurred In Response To This Rfi; All Costs Associated With Responding To This Rfi Will Be Solely At The Interested Party’s Expense. Interested Parties Are Responsible For Adequately Marking Proprietary Or Competition Sensitive Information Contained In Their Response. Proprietary Information Will Be Safeguarded In Accordance With The Applicable Government Regulations. Failure To Respond To This Rfi Does Not Preclude Participation In Any Future Associated Rfp That May Be Issued. background/purpose/technical Requirements the Naval Air Warfare Center Aircraft Division (nawcad) Webster Outlying Field (wolf) Division Is Soliciting Information And Comments From Industry On Its Ability To Provide Non-developmental Or Commercial Off The Shelf (cots) Network Radio Gateways (nrg) For Integration Into Full Scale Deployable And Scalable Transit Case Systems. The Nrgs Will Function As A Voice And Data Conferencing Center For Tactical And Commercial Radios, Internet Protocol Based Systems, And Cellular Phones. responses requested Information section 1 Of The Response Shall Provide Administrative Information, And Shall Include The Following As A Minimum: organization Name, Mailing Address, Overnight Delivery Address (if Different From Mailing Address), Phone Number, Fax Number, And Name And E-mail Of Designated Point Of Contact. business Type (large Business, Small Business, Small Disadvantaged Business, 8(a)-certified Small Disadvantaged Business, Hub Zone Small Business, Woman-owned Small Business, Very Small Business, Veteran-owned Small Business, Service-disabled Veteran-owned Small Business). country Of Origin For Main Component(s) section 2 Of The Response Shall Provide Technical Information, And Shall Include The Following As A Minimum: interested Parties Shall Respond With Existing Capabilities Or Products That Meet All Or A Subset Of The Aforementioned Attributes. Reponses That Include Information Detailing Potential Tradeoffs Or Alternative Solutions Is Encouraged. respondents Should Provide A Detailed Description Of The Following Characteristics Of Their Solution In Their Submission: product Specification, Sketches, Or Listings Of Authorized Distributors Are Not To Count As Part Of The Page Count. list Of Certifications/standards/compliances (military Standards, Etc.) operation minimum And Maximum Operating And Storage Temperatures (in Fahrenheit) humidity Range In Relative Humidity (operating & Non-operating) features dimensions (height X Width X Depth) environmental Conditions ruggedization (if Any) connectors power other radio Types Supported radio Interfaces Supported licensing Structure disa Approved Products List Integrated Tracking System (aplits) Tracking Number (tn) client Interface Description input/output Interfaces fault Reporting power other Information total Quantity Of Units Sold To Date date Of Delivery Of The First Unit date Of Delivery Of Most Recent Unit basic And Extended Warranty Information time To Production if Applicable And Able, Respondents Shall Include A List Of Department Of Defense (dod), Department Of Justice (doj) Or Department Of Homeland Security (dohs) Programs Of Record That Currently Employ Their Solution. It Would Be Helpful If A Sponsor Poc For Each Program, With Email Address And Phone Number Could Be Identified. the Government Is Interested In Receiving Vendors’ Price Lists For Items They Believe Meet The Need In This Rfi. Supplying Price Data Does Not Imply A Contractual Obligation And Must Be Provided And Marked As Price Data. respondents Should Include A List Of Authorized Distributors. additional Information in Response To This Rfi, Respondents Shall Submit Written Responses, Not-to-exceed Ten (10) Pages In Length Via Electronic Mail. Product Specification, Sketches, Or Listings Of Authorized Distributors Will Not Count Toward The Page Limitation. The Government Is Interested In Identification Of Long Lead Items(s), Sub-systems(s), Or Systems(s). the Government Does Not Intend To Award A Contract On The Basis Of This Request Or To Otherwise Pay For The Information Solicited. Proprietary Information Will Be Safeguarded In Accordance With The Applicable Government Regulations. All Information Received In Response To The Rfi That Is Marked Proprietary Will Be Handled Accordingly. The Government Will Not Be Liable For Or Suffer Any Consequential Damages For Any Proprietary Information Not Properly Identified. Responses To This Rfi May Not Be Returned. Respondents May Not Be Notified Of The Result Of The Review. failure To Respond To This Rfi Does Not Preclude Participation In Any Future Associated Rfp That May Be Issued. Information Provided In No Way Binds The Government To Solicit Or Award A Contract. It Is The Potential Vendor’s Responsibility To Monitor This Site For The Release Of Any Follow-on Information. how To Respond interested Parties Are Requested To Respond To This Rfi With A Pdf Document Format. Responses Shall Be Limited To 10 Pages And Submitted Via E-mail Only To Truman.b.harris3.civ@us.navy.mil. Proprietary Information, If Any, Should Be Minimized And Must Be Clearly Marked. Responses Are Due No Later Than 24 January 2024, 10:00 A.m. Est. responses To This Rfi May Not Be Returned. Respondents May Not Be Notified Of The Result Of The Review. It Is The Potential Vendor’s Responsibility To Monitor This Site For The Release Of Any Follow-on Information.

Details: The National Institute Of Diabetes And Digestive And Kidney Diseases (niddk) Seeks Industry Partners For Clinical Research Collaborations On Therapeutics, Diagnostics Or Devices For The Liver Cirrhosis Network the National Institute Of Diabetes And Digestive And Kidney Diseases (niddk) Of The National Institutes Of Health (nih) Of The Department Of Health And Human Services (dhhs) Has Released Requests For Applications Rfa-dk-20-003 And Rfa-dk-20-004 For The Establishment Of The Liver Cirrhosis Network; And Seeks Industry Collaborators To Provide Novel Or Repurposed Therapeutic Agents, Diagnostic Markers, Biomarkers, Devices, Or Services For Use In Nih-sponsored Multi-center Clinical Trials And Ancillary Studies In Adult Patients With Advanced Liver Disease And Cirrhosis; And The Hepatic And Extrahepatic Related Complications Emanating From Cirrhosis. background: The Niddk Is Proposing The Establishment Of The Liver Cirrhosis Network Through Funding Opportunity Announcements Rfa-dk-20-003 Seeking Clinical Centers; And In Conjunction With Rfa-dk-20-004 Seeking A Single Scientific Data Coordination Center, In Order To Promote Clinical And Translational Research On Cirrhosis Of The Liver And Related Complications In Adults. cirrhosis Represents Not A Single Disease But Is Rather The Consequence And Major Serious Outcome Of Many Chronic Liver Diseases, Caused By A Wide Range Of Conditions. The Etiologies Of Cirrhosis In The United States Include Infectious Causes Such As Chronic Hepatitis B, C And D; Genetic Causes Such As Wilson Disease, Hemochromatosis And Alpha-1-antitrypsin Deficiency; Metabolic Causes Such As Nonalcoholic Steatohepatitis; Autoimmunity Such As Autoimmune Hepatitis, Primary Biliary Cholangitis And Sclerosing Cholangitis; And Toxic Causes Such As Alcohol-associated Liver Disease And Chronic Liver Injury From Medications Such As Methotrexate And Amiodarone. Cirrhosis From These Diseases Is Almost Always The Result Of Chronic Injury With Persistent Inflammation And Cell Damage That Results In Faulty Healing And Fibrosis. As Fibrosis Accumulates It Causes Distortion Of The Architecture Of Liver, Portal Hypertension And Compromise Of Liver Function. Clinical Complications Of Cirrhosis Include Symptoms Of Fatigue, Weakness, Weight Loss, Itching And Jaundice; Gastrointestinal Bleeding From Varices Or Portal Hypertensive Gastropathy, Coagulopathy, Ascites And Disturbance Of Fluid And Electrolyte Balance, Renal Dysfunction And Hepatic Encephalopathy. The Most Dreaded Complication Of Cirrhosis Is Hepatocellular Carcinoma, A Highly Fatal Cancer That Arises In 1 To 3% Of Persons With Cirrhosis Yearly. Once Cirrhosis Is Present, Treatment Of The Underlying Liver Disease Can Lessen Further Progression And Deterioration, But Does Not Eliminate All Risk Of Complications, Particularly Hepatocellular Carcinoma. mortality Due To Liver Disease Remains A Significant Public Health Burden In The United States, Currently Ranked 11th Overall And Ranking 6th In Persons Below The Age Of 65 Years. Cirrhosis Appears To Be Rising In Some Populations Such As Persons Living With Hiv Infection, Nonalcoholic Fatty Liver Disease And Cystic Fibrosis. Hepatocellular Carcinoma Incidence Is Also Rising In The United States And Is A Surrogate For The Prevalence Of Cirrhosis. treatment Of Underlying Causes Of Chronic Liver Disease Such As Antivirals For Chronic Hepatitis B And C; Therapeutic Phlebotomy For Genetic Hemochromatosis; Ursodiol For Primary Biliary Cirrhosis; Weight Loss For Nonalcoholic Steatohepatitis (nash), And Cessation Of Alcohol Consumption For Alcohol-associated Liver Disease, All Underpin The Overarching Clinical Approach To Prevent The Development Of Cirrhosis By Early Abrogation Of Ongoing Injury To The Still Noncirrhotic Liver. Neutralization Of The Liver Disease Etiology May Allow The Injured Liver To Invoke Endogenous Mechanisms To Reverse The Consequences Of Chronic Inflammation And The Accumulation Of Mild Or Even Modest Amounts Of Liver Fibrosis. However, Once Advanced Fibrosis Or Cirrhosis Has Been Established, Neutralization Of The Causes Of Liver Disease Generally Will Not Reverse Fibrosis Or Cirrhosis Completely. While The Residual Risk Of Complications May Be Decrease, This May Be Off-set By The Improvement In Survival, So That Patients With Cirrhosis And Advanced Fibrosis Will Live And Be At Risk For The Complications Longer. liver Transplantation Is Currently The Only Medically Viable Avenue For Patients With End-stage Liver Disease That Will Extend Their Longevity. On An Annual Basis, Despite Treatment Success Rates For Chronic Hepatitis C And Other Liver Diseases, The National Wait List For Liver Transplantation In The United States Remains Essentially Unchanged At Approximately 13,000 Patients. Only 8000 Liver Transplantations Are Performed Annually. However, Far, Far More Patients With End-stage Liver Disease Are Not Even Placed On Liver Transplantation Lists For A Variety Of Co-morbid Or Psychosocial Issues. given The Discrepancy Between The Need And The Availability Of Liver Organs For Patients On Liver Transplant Waiting Lists And The Even More Numerous Patients Who Are Unable To Be Considered For Listing For Liver Transplantation, There Is A Significant Need To Improve Our Understanding Of Clinical And Translational Scientific Aspects Of Liver Fibrosis And Cirrhosis. In Addition, There Is A Need For Furthering Fundamental Understanding Of Both The Underlying Pro- And Anti-fibrotic Mechanisms As Well As Risk Factors And Mechanisms That Accentuate Pro- And Anti-fibrotic Processes. study Goals: The Overall Goal Of The Liver Cirrhosis Network Is To Promote Clinical And Translational Research That Will Advance The Understanding Of Liver Fibrosis And Cirrhosis Pathophysiology; Improve Clinical Management Of Liver Cirrhosis And Complications Of Advanced Fibrosis; And To Conduct Clinical Trials To Alter Cirrhosis Liver Disease Trajectory And The Related Complications. While Specific Details Of The Protocols For The Liver Cirrhosis Network Are Yet To Be Defined And Will Be Made By Consensus By The Future Steering Committee Of The Network, It Is Expected That Sufficient Numbers Of Subjects Will Be Enrolled With Either Stable, Child Class A, Cirrhosis Or Evidence Of Advanced Fibrosis (such As Bridging Fibrosis On Liver Biopsy Or Evidence Of Advanced Disease As Assessed By Validated Non-invasive Markers) To Operationalize The Eventual Network Studies. An Attempt Will Be Considered To Enroll Subjects With All Forms Of Cirrhosis (viral, Autoimmune, Genetic, Toxic, Alcohol-associated And “cryptogenic”) And With A Diverse Range Of Demographics As Typifies Chronic Liver Disease In The United States. the Liver Cirrhosis Network Is Interested In Conducting Research That Will Lead To Improved Clinical Outcomes In Adults With Cirrhosis And Advanced Liver Disease With Industry Collaborators To: • Evaluate The Natural History, Pathogenesis, Diagnosis, Genetic Factors, Genomics, Proteomics, Metabolomics, Lipidomics, Epigenomics, Imaging Studies, And Determinants Of Progression And Severity Of Advanced Liver Disease And Cirrhosis-related Complications • Explore Use Of Serum Markers For Fibrosis And Serum Markers For Disease Activity To Predict Hepatic Histology Or Function Either By Themselves Or In Combination With Other Clinical, Laboratory, Genomic, Proteomic, Metabolomic, And Lipidomic Variables • Explore The Utility Of These Serum Markers As Surrogate Markers Of Therapeutic Response In Study Subjects Participating In Treatment Trials • Investigate Proprietary Or Repurposed Drugs (such As Statins, Anti-fibrogenic Agents, Autophagy Inducers, Chemo-preventive Agents, Nonsteroidal Anti-inflammatory Agents, Etc.), Reagents, Or Devices In Controlled Randomized Clinical Trials As Potential Diagnostics Or Therapies For Advanced Liver Disease, Cirrhosis And Cirrhosis Related Complications • Evaluate Noninvasive Imaging Methods For Assessing Fibrosis, Portal Vein Hypertension, Hepatic Function, Screening For Or Diagnosis Of Liver Cancer, And Parenchymal Pathology In Cirrhosis Liver Disease Including But Not Limited To The Use Of Elastography, Nuclear Magnetic Resonance Imaging, And Molecular Imaging. • Evaluate The Use Of Cytokine Assays For Analyses Of Serum/plasma Cytokine Levels As Markers Of Disease Activity And As Surrogate Markers Of Histologic Or Clinical Improvement In Therapeutic Trials capability Statement: Commercial Organizations Interested In Pursuing Clinical Collaborations With Niddk For Cirrhosis Liver Disease Are Required To Submit A Capability Statement To The Niddk. The Capability Statements Submitted In Response To This Announcement Will Be Used To Evaluate And Select Industry Collaborators. The Capability Statement Should Not Exceed 10 (ten) Pages Of Narrative (not Including Appendices) And Should Include The Following Information: 1. A Description Of The Therapeutic, Diagnostic Or Device Proposed To Be Used In The Clinical Research Study. (note: The Proposed Therapeutic Or Device Must Have Been Tested Already In A Phase I Trial In Humans.) 2. The Specific Details Of The Methods To Be Utilized In The Investigation Of The Pharmacologic, Surgical Or Device Intervention In Patients With Cirrhosis Liver Disease, And A Clear Description Of The Important Issues Surrounding The Evaluation Of Disease Progression In These Patients. 3. A Detailed Plan Demonstrating The Ability To Provide Sufficient Quantities Of The Therapeutic, Diagnostic Or Device Either In Total Prior To Study Initiation (preferred If Possible) Or In A Timely Manner For The Duration Of The Study. 4. A Description Of All Laboratory Tests That Are Needed And Proficiency In Conducting These Laboratory Tests, Including Assays And Required Amount Of Specimens, To Determine Specific Biomarker(s) Levels And List Potential Biomarkers, Along With Appropriate Methods For Performing Such Tests. 5. A Description Of Other Core Facilities And Interactions With Core Facilities That Are Needed For The Study. 6. Dosing, Pharmacodynamic, And Pharmacokinetic Data From Human Studies For Any Novel Therapeutics. 7. Adverse Event Profile For The Proposed Therapeutic Or Device. 8. A Description Of The Practices And Procedures That Would Be Used To Assure Patient Privacy And Maintain Confidentiality Of Data Obtained From The Study. 9. (optional) Outcome Measures Of Interest To The Organization. The Specifics Of The Proposed Outcome Measures Should Include But Not Be Limited To Treatment And Evaluation Of Cirrhosis Liver Disease Or Cirrhosis Related Complications. 10. Any Other Resources The Organization Proposes To Commit To The Collaboration (in Addition To The Proposed Therapeutic, Diagnostic Or Device), Which May Include Any Of The Following: Equipment, Reagents, Supplies, Access To Facilities, Personnel Or Services, And, If Appropriate, Funding (pursuant To A Cooperative Research And Development Agreement (crada) Authorized Under 15 U.s.c. § 3710a), To Help Support The Conduct Of The Clinical Study. 11. Affirmative Statements That The Organization: a. Agrees To Provide A Letter Of Cross Reference To The Drug, Biologic Or Device Master File For The Proposed Therapeutic Or Device, Which Will Be Included With Any Us Fda Filing By The Ind Or Ide Sponsor Of The Liver Cirrhosis Network Study; b. Agrees To Have The Proposed Therapeutic, Diagnostic Or Device Used In The Liver Cirrhosis Network-developed Protocols Which Will Be Conducted By The Liver Cirrhosis Network Research Network For Which The Study Data Collection And Analysis Will Be Performed By The Liver Cirrhosis Network Scientific And Data Coordinating Center; c. Agrees To Assure Patient Privacy And Will Maintain Confidentiality Of Data Obtained From The Study; d. Agrees To Share All Safety Data From Other Studies Involving The Proposed Therapeutic Or Device As Well As Relevant Efficacy Data From Other Studies (updated Investigator Brochure, Etc) With The Liver Cirrhosis Network; e. Understands That Because The Liver Cirrhosis Network Is Supported By Niddk Funding, The Study Results Will Be Published And Therefore Agrees To The Prompt Publication Of Research Results From The Clinical Study Using The Organization's Proposed Therapeutic, Diagnostic Or Device; f. Has Intellectual Property Rights To Provide Laboratory Test/biomarker(s), Therapeutic Or Device To Niddk For Testing And Has No Current Agreements Or Arrangements That Could Impede This Right; And f. Understands That The Clinical Study Will Be Conducted Under An Agreement With Niddk Which Must Adhere To Phs Intellectual Property Policies (see: Http://www.ott.nih.gov/policy/phspat_policy.aspx). submission: Capability Statements Received By Niddk Will Be Considered. Prospective Collaborators May Be Invited To Attend, At Their Own Expense, A Liver Cirrhosis Network Steering Committee Meeting To Be Held In The Baltimore-washington, Dc Area To Discuss The Information In Their Capability Statement With The Steering Committee Members. Note:no Funds Will Be Provided By Niddk To Any Organization Selected For This Clinical Research Collaboration Opportunity. submision And Inquiries: Submit Capability Statements To: noo Coordinator, National Institute Of Diabetes And Digestive And Kidney Diseases e-mail: Niddkottdip@niddk.nih.gov for Scientific Inquiries Contact: edward Doo, Md, director, Liver Diseases Research Program division Of Digestive Diseases And Nutrition, Niddk 6707 Democracy Blvd., Room 6149 bethesda, Md 20892-5450 telephone: (301) 451-4524 fax: (301) 480-8300 e-mail: Dooe@niddk.nih.gov for Inquiries Regarding Partnering With Niddk (intellectual Property Matters And Collaboration Agreements) Contact: agnes Rooke, Jd technology Advancement Office niddk, Nih, Hhs telephone: 301-451-6072 e-mail: Agnes.rooke@nih.gov this Notice Of Opportunity Is Also Posted At: Http://techdev.niddk.nih.gov/collabs.shtml.

Details: Aflcmc Data Operations Cso 1.0 Overview this Commercial Solutions Opening (cso) Is Intended To Be A Streamlined Vehicle To Allow For The Establishment Of A Modern Data Operations (dataops) Solution Supporting A Variety Of Critical National Security Systems. This Cso Authority Is Established Under Section 803 Of The National Defense Authorization Act (ndaa) For Fiscal Year (fy) 2022 (pub. L. 117-81) And Class Deviation 2022-o0007. The Air Force Life Cycle Management Center (aflcmc) Programs Require The Utilization And Leveraging Of The Latest Technology Advances From A Large Variety Of Prospective Contractors. Aflcmc Invites Innovating Technical Approach Proposals Addressing All Aspects Of Dataops Focusing On The Below Objective Areas. However, These Enumerated Focus Areas Are Minimum Requirements, And Aflcmc Is Open To The Identification Of Technologies Useful For Modernizing Dataops For Sophisticated Security And Weapon Systems. This Requires Delivering An Enduring, Secure, Robust, Efficient, Responsive, Agile, Elastic, And Extensible Classified Dataops Solution. This Cso Will Focus On Existing And Emerging Technologies And Platforms Across Aflcmc, Department Of The Air Force (daf), Department Of Defense (dod) And The Intelligence Community, As Well As Leveraging Commercial Markets To Perform An Integrated Analysis Of The Capabilities Of Varying Technologies That Support Our Critical National Security Systems And Prioritize Investments Over Time. the Cso May Result In The Award Of Far Part 12 Contracts Or Other Transaction Agreements (otas) Under 10 Usc 4022, Through Calls Via Amendments To The Cso. The Government Anticipates Future Calls To Be Competitively Solicited. These Calls Will Contain Specific Areas Of Interest, User Stories And/or Problem Statements Related To Program Specific Dataops Focus Areas. These Specific Areas Of Interest Are What Prospective Contractors Shall Focus Their Solutions Towards. The Government Reserves The Right To Issue Separate Calls For Each Dataops Focus Area Or Combine Several Focus Areas Under An Individual Call. disclaimer: No Proposals Or White Papers Are Being Requested At This Time. Those Will Be Requested Via Calls Published Under The Cso Solicitation. aflcmc Is Not Obligated To Make Any Awards From Any Publicized Call, And All Awards Under This Cso Are Explicitly Subject To The Availability Of Funds And Successful Negotiations. The Government Is Not Responsible For Any Monies Expended By Any Vendor Prior To The Issuance Of Any Awarded Contract/agreement. Aflcmc Reserves The Right To Modify The Solicitation Requirements Of This Cso And Each Subsequent Call At Its Sole Discretion. this Cso Seeks To Fund Innovative Technologies That Propose New Solutions To Expand Aflcmc’s Capabilities As It Relates To Modern Dataops Focus Areas. Aflcmc Is Interested In Capabilities From All Interested Vendors To Include, But Not Limited To, Traditional Defense Contractors, Nontraditional Defense Contractors, Large Businesses, Small Businesses, And Research Institutions (collectively Referred As Vendors). It Should Be Noted, Many Of The Critical National Security Systems Operate In Varying Classification Environments, Including Highly Classified Environments – Such As Collateral, Sensitive Compartmentalized Information, And Special Access Program. Though Some Dataops Focus Areas May Require Unclassified Work, Respondents Should Be Aware That Vendors Cleared To Work, Or The Ability To Be Cleared To Work, In Highly Classified Environments Will Be Necessary For Any Award. The Cso Is A Streamlined Acquisition Process That Seeks To Reduce Acquisition Timelines And Acquire New, Innovative Solutions That Vendors Can Bring Forth To Meet The Stated Areas Of Interest Detailed In Each Call. 2.0 Dataops Technology Focus Areas aflcmc Is Seeking Capabilities To Prove Out End-to-end Dataops For Representative Modern Embedded Weapon Systems. The Desired End-state Is A Dataops Capability/prototype That Enables A Weapon System To Exploit Data Across The Full Lifecycle Of An Embedded Weapon System (development, Integration, Test, Deployment, Operations And Sustainment) Across All Classification Levels. An Ideal Partner Has First-party Ability To Directly Modify Underlying Commercial Hyperscale And Edge Cloud Fabric To Meet The Project’s Requirements Across All Classification Levels And Supporting Partners Would Be Considered As Enabling Providers Supporting Specific Aspects Of The Potential Solution. each Technology Focus Area Identifies An Area Where Prospective Vendors Can Bring Substantial Value To Meet The Dataops Mission. These Focus Areas Are Meant To Be Read Expansively And Are Not Limited To The Enumerated Focus Areas. Additional Focus Areas May Be Included Via Amendments To This Cso. Aflcmc Prefers To Bucket Several Focus Areas Into Singular Calls, Which Means Vendors That Can Optimize Several Focus Areas Will Be Preferred. Aflcmc Requires Provider(s) To Deliver An Innovative State-of-the-art Commercial Solution That Innovates All Or Some Of The Following Capability Areas. whether Using A Single Vendor Or Using Multiple Vendors, Aflcmc’s Intended Minimum Viable Product (mvp) Should Contain The Following Six Foundational Attributes: 1. Hybrid Cloud Iaas, Paas, Saas: aflcmc Seeks Solutions For Infrastructure As A Service (iaas), Platform As A Service (paas), And Software As A Service (saas) That Can Be Hosted In A Hybrid Cloud Architecture. For The Purposes Of This Cso, “hybrid Cloud” Is Defined As: A Virtual Environment Provided To A Single Customer That Combines Private Cloud Compute, Storage, And Services Running On-premises With Compute, Storage, And Services Running In A Public Cloud Along With The Ability To Move Information Seamlessly And Transparently Between Them. All Offerings Will Be Templated, Extensible, And Elastically Scalable On Converged And/or Hyperconverged Infrastructure. All Offerings Will Support “bring Your Own ‘x’,” Such That Aflcmc Can Re-host Existing Workloads Without Interruption. All Offerings Will Comply With Relevant Department Of Defense Instructions, Regulations, And Policies Such That They Will Be Readily Accreditable And Interoperable With Existing Dod Networks And Information Systems At The Unclassified, Secret, And Top-secret Classification Levels. Additionally, All Offerings Will Be Accredited Or Readily Accreditable To Handle Special Access Program (sap) And Sensitive Compartmented Information (sci) Handling Caveats At The Secret And Top-secret Classification Levels. 2. Information Transport aflcmc Is Seeking Solutions For Information Transport That Complies With Relevant Department Of Defense Instructions, Regulations, And Policies Such That Any Transport Solution Offering Will Be Readily Accreditable And Interoperable With Existing Department Of Defense Information Networks (dodin). Information Transport Offerings Will Also Be Required To Interoperate With The Hybrid Iaas, Paas, And Saas Solutions Offered Under Technology Focus Area (1). All Information Transport Offerings Must Operate In Multi-level Classification Environments, Enabling Multi-modal Connectivity From Anywhere In The Continental United States (conus) Via A High-bandwidth/low-latency Transport Solution. Cryptographic Transport Shall Meet National Security Agency (nsa) Type 1 Encryption Products Or Equivalent Cryptographic Solutions. Further, Aflcmc Requires Capability To Support Edge Resources To Operate In Disconnected, Intermittently Connected Or Low-bandwidth (dil) Environments. Initial Connectivity Shall Encompass Wright-patterson Air Force Base (afb), Edwards Afb, Tinker Afb And An Off-base Facility In The Dayton, Ohio Greater Metropolitan Area. 3. Fielding Operations aflcmc Is Seeking Solutions To Rapidly Deploy The Solutions Acquired Under Focus Areas (1) And (2). To Support Our System Program Offices, Aflcmc Desires Rapid “full Network/crypto” Deployability To New Locations Within 30 Days From Award. Connections Should Include All Enterprise Capabilities Such As Nipr, Sipr, Jwics, Existing Classified, Sap Capable, Hyper-elastic Cloud Regions And Other Program Networks. Moreover, Aflcmc Seeks Automated Disaster Recovery Functionality To Support Continuity Of Operations (coops). 4. Crypto-net Managements/commercial Solutions For Classified aflcmc Requires Innovative Commercial Products To Be Used To Protect Classified Data, Including Both Data-in-transit (dit) And Data-at-rest (dar). To The Maximum Extent Practicable, Technologies For Aflcmc Shall Be Procured In Accordance With Requests Commercial Solutions For Classified (csfc) Services To Comply With The Committee On National Security Systems Policy (cnssp) No. 11, National Policy Governing The Acquisition Of Information Assurance And Ia-enabled Information Technology Products.” 5. Network Operations Center (noc) / Security Operations Center (soc) aflcmc Is Seeking Solutions To Support, Enable, And Augment Network Administration And Cybersecurity Operations For Solutions Acquired Under Focus Areas (1) And (2). Solutions Will Include Services That Enable Real-time And Near Real-time Metering, Auditing, Logging, Monitoring, And Status Reporting Of The Entire Virtual Environment. 6. Help Desk aflcmc Requires A Customer Support Help Desk To Assist End-users In Navigating, Utilizing And Accessing Data Within The Cloud Environments. Aflcmc Envisions A Software-as-a-service That Can Manage All Communication And Network Channels, Establish Performance Metrics And Monitoring, And Is Maximally Available To Meet Mission Requirements. aflcmc Is Interested In Additional Focus Areas Beyond The Above Six (6) Foundational Dataops Focus Areas. Aflcmc May Issue Calls Against The Below Supplemental Focus Areas. These Supplemental Focus Areas Are Meant To Be Read Expansively And Not Limited To The Enumerated Areas. Additional Focus Areas Beyond Those Enumerated Below May Be Included Via An Individual Call Against This Cso. Vendors That Meet Some Or All The Above Focus Areas May Also Identify Capabilities For The Additional Focus Areas. i. Secure Access Service Edge aflcmc Has A Requirement To Provide Consistent, Fast And Secure Access To Dispersed End Users Operating In Permanent Military Installations As Well As Forward Operating Base. Services Should Establish Identity-driven Security Compliant With Us Government Security Parameters For All Classification Levels (unclassified, Secret, Top Secret And Sap Programs). ii. Software-defined Networking (sdn) aflcmc Has A Requirement To Explore Implementing Sdn For Fully Networked Command, Control And Communications (c3) Functionality, Particularly In Day-to-day Military Operating Base (mob) And Sustainment Missions. Sdn Should Contain A High Degree Of Network Programmability And Reconfigurability To Meet The Needs Of Different Government Systems And Emphasize Advantageous Situational Awareness For Faster Response Times. Further, Aflcmc Is Interested In Other Ways Sdn Can Be Applied To Military Environments While Preserving Data Security. iii. Edge Hyper-converged Infrastructure aflcmc Anticipates Migrating Away From Discrete, Hardware-defined Systems Toward Software-defined Environments Permitting All Functionality Through Commercial Service Platforms While Protecting Data At All Classification Levels (unclassified, Secret, Top Secret, Sap). iv. Zero Trust Architecture given The Security Posture Of Many Programs, Aflcmc Requires Zero Trust Security Architecture By “never Trusting, Always Verifying” Network Security. Aflcmc Desires Strong Identity Verification, Validation Of Device Compliance Before Granting Access And Ensuring Least Privilege Access. v. Infrastructure As Code (iac) infrastructure As Code Is The Process Of Managing And Provisioning Computer Data Centers Through Machine-readable Definition Files, Rather Than Physical Hardware Configuration Or Interactive Configuration Tools. Aflcmc Seeks Partners Who Would Be Able To Expedite The Onboarding Process For New Players By Inflating An Iac Instance Within A Cloud Environment, Enabling Immediate Executability Of Licenses, Cloud Resource Management, And Other Capabilities. vi. Cloud Native Design on-premises (on-prem) Infrastructure Comes With An Immense Number Of Limitations As Well As A High Threshold For Entry For New Players In Terms Of Hardware Investments And Schedule Lead Times. Utilization Of Cloud Native Designs For All Network Mapping, Tooling, Iaas, Etc. Is Of Extreme Interest To Aflcmc. vii. Software Defined Perimeter Enabling Classified Data Processing aflcmc Participates In Work Ranging From Cui All The Way Up To Ts/sar/sci. Having Cloud Native, Logically Defined Perimeters Around Separate Enclaves That Exist At Various Classification Levels Is Critical To Mission Success. Organizations Should Be Prepared To Provide A Body Of Evidence To Demonstrate Logical Controls That Safeguard Information At Different Impact Levels (ils). viii. Augmented And Virtual Reality Capabilities (e.g., Training, Maintenance, Etc.) aflcmc Requires Commercial Augmented And Virtual Reality Capabilities To Assist Usaf Maintenance And Service Technicians To Interface With Usaf Systems. Applications Should Have Practical Maintenance Applications As Well As Training Capabilities. ix. Data Encryption (at Rest, In Motion, Fips 140-3) experience With Encrypting And Safeguarding Data Is Critical To Dod Success And Cybersecurity. Fips 140.3 Is The Standard That Shall Be Used In Designing And Implementing Cryptographic Modules That Federal Departments And Agencies Operate Or Are Operated For Them Under Contract. The Standard Provides Four Increasing, Qualitative Levels Of Security Intended To Cover A Wide Range Of Potential Applications And Environments. The Security Requirements Cover Areas Related To The Secure Design, Implementation, And Operation Of A Cryptographic Module. These Areas Include Cryptographic Module Specification; Cryptographic Module Interfaces; Roles, Services, And Authentication; Software/firmware Security; Operating Environment; Physical Security; Non-invasive Security; Sensitive Security Parameter Management; Self-tests; Life-cycle Assurance; And Mitigation Of Other Attacks. Organizations With Familiarization And Expertise With Establishing And Maintaining Compliant Data Encryption Could Be Of Use To The Dod. x. Cyber, Secure Processing due To The Sensitive Nature Of The Usaf Mission, The Ability To Leverage Cyber Secure Processing, Compliant With Dod Standards For All Impact Levels Is Required. xi. Machine Learning (ml) And Artificial Intelligence (ai) Data Factories aflcmc Seeks To Find New And Innovative Ways To Deploy And Enable Ai/ml To Identify Areas Of Interest Within Large Data Sets. These Data Factories Should Be Able To Pinpoint Concerns, Operational Or Safety Threats, And Shall Help Alleviate Human In The Loop (hitl) Man Hours Currently Required To Analyze Data Sets. xii. Big Data Capability (data Warehousing, Data Lakes, Restructured Data Engineering) test Sets Drive A Requirement To Capture, Transport, And Analyze Massive Amounts Of Data In Near-real-time, As Well As A Requirement To Host Portions Of That Data For An Indefinite Amount Of Time. Aflcmc Has Interest In Organizations That Have Experience With Long-term Data Lakes, And Data Storage With The Ability To Enable Petabyte And Exabyte Transport At High Speeds Between Various Conus And Oconus Locations. xiii. Continuous Integration (ci)/continuous Development (cd) Software Pipeline aflcmc Utilizes A Devsecops Framework For Many Of Its Projects. Ci/cd Pipelines Enable Alfcmc To Adapt To Emerging Threats. Entities With Experience In Optimization And Automation Of Ci/cd Pipelines Would Be Of Particular Use To The Dod. xiv. Application Development + Application Refactoring For Cloud Deployment aflcmc Sees A Future Use Case Of Being Able To Pull Data Developed From Another Dod Organization To Be Easily Digested And Absorbed From A Cloud Environment And Then Re-tooled To Meet Mission Requirements. Aflcmc Requires A Cloud-based Platform To Host Both The Outputs Of Application Development (ie App Store) As Well As A Toolkit To Refactor An Applications Targeted Use. xv. Existing Capability Refactoring/integration For Application Programming Interface (api) Microservice Architecture aflcmc Has A Potential Future Requirement To Establish A Microservice Architecture To Iteratively Build New Applications/capability Without Impacting Availability Of Systems. Aflcmc Requires Microservice Refactoring Within Designated Cloud-based Platforms. xvi. Reverse Engineering aflcmc Has A Potential Future Requirement For Reverse Engineering Services. In Instances Where Aflcmc Lacks Sufficient Engineering Data For Varying Aircraft Or Supporting System Parts, Aflcmc Desires The Ability To Conduct Reverse Engineering Services To Produce Underlying Engineering Data Necessary For Alternate Sourcing Of Parts Or Manufacturing Of The Parts. xvii. Additive Manufacturing aflcmc Desires Additive Manufacturing Services With The Capacity For Potential On-premises Manufacture Of Varying Parts. Aflcmc Seeks Commercial Application Of 3d Printers And Other Technologies That Permit Immediate Production Of Parts To Reduce Mission Incapable Awaiting Parts (micap) Status Of Critical Systems/assets. 3.0 Cso With Calls this Cso Is A Hybrid Solicitation Against Which Both Closed Calls And/or Open Period Calls Can Be Published Via Amendments To The Cso. All Calls Issued Under This Cso Will Include Specific Instructions Including Dates, Areas Of Interest/focus Areas, Evaluation Criteria And Proposal Instructions To Offerors. While Each Offer Shall Adhere To This Cso, The Calls May Contain Other Information Of Which The Proposing Vendors Should Also Strictly Adhere. Each Call Will Be Announced On The Government Point Of Entry (beta.sam.gov), Which May Result In The Award Of A Far Part 12 Contract Or An Other Transaction Agreement (ota) Under 10 Usc 4022. 3.1 Closed Calls (one-step Or Two-step) over The Period Of This Cso, Calls May Be Issued To Request White Papers And/or Proposals For Specific Areas Of Interest/focus Areas. It Will Be Determined On A Call-by-call Basis Whether The Announcement Is For A One-step (proposals Only) Or A Two-step Process (white Paper First, Then Proposals By Invite-only). The Submission For White Papers And Proposals Shall Be Submitted At A Specific Date And Time As Set For In Each Particular Call. White Papers And/or Proposals May Not Be Reviewed If Submitted After The Stated Date And Time. 3.1.1 One-step Calls step 1: Proposal Due Date And Time Will Be Provided In Calls Issued Against This Cso. Aflcmc Will Make Selections From Vendor Proposals Only In Accordance With The Evaluation Criteria Contained In The Call. 3.1.2 Two-step Calls step 1: White Paper Due Date And Time Will Be Provided In Calls Issued Against This Cso. Aflcmc, At Its Sole Discretion, May Or May Not Request A Presentation Or Discussion With Government Personnel About The White Paper. step 2: Proposal Due Date And Time Will Be Provided In Requests For Proposal (rfps) Sent To Offers That Submit White Papers Who Are Evaluated Favorably In Accordance With The Evaluation Criteria Contained In Each Call. 3.2 Open Period Calls (two-step) this Cso May Also Have Open Period Calls. Open Period Calls Will Only Be Issued Under A Two-step Process (see 3.1.2 Above). After An Open Call Is Published, White Papers May Be Submitted At Any Time During An Open Period For The Areas Of Interest/focus Areas Detailed Within The Call. It Is Important To Note That Only White Papers Submitted In Response To Specific Areas Of Interest/focus Areas Detailed In The Call Will Be Considered. step 1: White Paper Due Date And Time Will Be Provided In Calls Issued Against This Cso. Aflcmc, At Its Sole Discretion, May Or May Not Request A Presentation Or Discussion With Government Personnel About The White Paper. step 2: Proposal Due Date And Time Will Be Provided In Requests For Proposal (rfps) Sent To Offers That Submit White Papers Who Are Evaluated Favorably In Accordance With The Evaluation Criteria Contained In Each Call. 4.0 Definitions cso With Calls: This Allows For The Publication Of An Umbrella Cso Solicitation That Contains Overarching Information But Does Not Request White Papers Or Proposals. The Cso Functions As A Framework Identifying The Technical Areas And Giving The Basic Terms And Administrative Information Of The Cso. The Requests For White Papers And/or Proposals Are Done By Issuing Calls That Are Published Via Amendments To The Cso. Calls Can Be Issued At Any Time During The Period Of Performance Of The Cso. Each Call Will Be Tailored To Best Fit The Acquisition Approached Identified By The Government. The Calls May Also Include Specific Terms And/or Conditions That Apply To That Particular Call Such As Technical Details, Security Requirements And/or Other Pertinent Clauses. Proposals Or White Papers Are Submitted Only When Calls Under This Cso Are Published. open Period Calls: This Type Of Call Allows For White Paper And Proposal Submittals At Any Time Within A Specified Period As Set Forth In The Subsequent Call. closed Calls: This Type Of Call Allows For White Paper And/or Proposal Submittals At A Specified Date And Time As Set Forth In The Subsequent Call. This Process And The Dates Associated With It Are More Structured Than Open Period Calls. areas Of Interest/ Focus Areas: These Are Specific Requests For Innovative Solutions That Aflcmc Will Detail In Each Subsequent Call And Will Derive From The Technology Focus Areas (2.0 Above). Vendor’s Innovative Solutions Should Focus On Addressing The Specific Technology Focus Areas Contained Within A Specific Call. white Paper: A Brief (usually 2-5 Pages) Summary Of The Proposed Technical Approach With An Accompanying Rough Order Of Magnitude (rom) Price. pitch Day: Pitch Day Is A Tool That Can Be Used As Part Of The Call Process. When Used, Pitch Day Gives Vendors An Opportunity To Meet Aflcmc Personnel In-person And Provide A Pitch Of Their Proposed Technology. If A Pitch Day Is Utilized, Specific Details Explaining The Process And Evaluation Methods Will Be Contained Within A Specific Call. other Transaction: Refers To The Type Of Other Transaction Agreement (ota) That May Be Placed As A Result Of This Cso And Associated Calls. This Type Of Ot Is Authorized By 10 Usc 4022 For Prototype Projects Directly Relevant To Enhancing The Mission Effectiveness Of Military Personnel And The Supporting Platforms, Systems, Components, Or Materials Proposed To Be Acquired Or Developed By The Department Of Defense (dod), Or For The Improvement Of Platforms, Systems, Components, Or Materials In Use By The Armed Forces. This Type Of Ota Is Treated By Dod As An Acquisition Instrument, Commonly Referred To As An “other Transaction” For A Prototype Project Or A Section 4022 “other Transaction.” prototype Project: Can Generally Be Described As A Proof Of Concept, Model, Reverse Engineering To Address Obsolescence, Pilot, Novel Application Of Commercial Technologies For Defense Purposes, Agile Development Activity, Creation, Design, Development, Demonstration Of Technical Or Operational Utility, Or Combinations Of The Foregoing. A Process, Including A Business Process, May Also Be The Subject Of A Prototype Project. Although Assistance Terms Are Generally Not Appropriate In Ot Agreements In 10 U.s.c. 4022, Ancillary Work Efforts That Are Necessary For Completion Of The Prototype Project, Such As Test Site Training Or Limited Logistics Support, May Be Included In Prototype Projects. A Prototype May Be Physical, Virtual, Or Conceptual In Nature. The Quantity Of Prototypes/commercial Solutions Should Generally Be Limited To That Needed To Prove Technical Or Manufacturing Feasibility Or Evaluate Military Utility. innovative: This Refers To Any Technology, Process, Or Method, Including Research And Development That Is New As Of The Date Of Proposal Submission; Or Any New Application Of An Existing Technology, Process Or Method As Of The Proposal Date. nontraditional Defense Contractor: As Defined In 10 U.s.c. 2302(9) As An Entity That Is Not Currently Performing And Has Not Performed, For At Least The One-year Period Preceding The Solicitation Of Sources By The Dod For The Procurement Or Transaction, Any Contract Or Subcontract For The Dod That Is The Subject For Full Coverage Under The Cost Accounting Standards Prescribed Pursuant To 41 U.s.c. 1502 And The Regulations Implementing Such Section. This Includes All Small Business Concerns Under The Criteria And Size Standards In 13 C.f.r. Part 121. small Business Concern: Defined In The Small Business Act (15 U.s.c. 632) And 13 C.f.r. Part 121. 5.0 Contract/agreement Details as Stated In The Overview Section, Calls Issued Under This Cso Can Result In The Award Of Either A Far Part 12 Contract Or An Other Transaction Agreement (ota) Under 10 U.s.c. 4022. Regardless Of The Contract Instrument, Aflcmc Chooses To Pursue The Contract/agreement Type For All As Fixed Price, Which Includes Firm Fixed Price (ffp) And Fixed Price Incentive (fpi). Future Solicitations Are Not Accepting Offers For Grants Or Cooperative Agreements As The Purpose Of This Cso Is To Transfer Something Of Value Directly To The Government. the Government Will Be The Sole Decision Authority On Whether To Pursue A Far Part 12 Contract, An Ota Or No Award At All. The Government Reserves The Right To Award Some, All Or None Of The Proposal From The Responses To Each Call. The Contracting/agreements Officer Reserves The Right To Negotiate Directly With The Offeror On The Terms And Conditions Prior To Execution Of The Resulting Contract/agreement On Behalf Of The Government. Be Advised That Only A Contracting/agreements Officer Has The Authority To Enter Into, Or Modify, A Binding Contract/agreement On Behalf Of The United States Government. 5.1 Prototyping this Cso May Result In The Award Of Prototype Projects, Which Include Not Only Commercially Available Technologies Fueled By Commercial Or Strategic Investment, But Also Concept Demonstrations, Pilots, And Agile Development Activities That Can Incrementally Improve Commercial Technologies, Existing Government-owned Capabilities, And/or Concepts For Broad Defense And/or Public Application. The Government Reserves The Right To Award A Far Part 12 Contract Or An Other Transaction (ot) Under 10 U.s.c. 4022 Agreement (including An Ot For A Prototype Project And A Follow-on Ot Or Contract For Production), Or A No Award At All. Calls Issued Under This Cso Constitute Competitive Procedures. Aflcmc May Competitively Award Ots For Prototype Projects That Provide For The Award Or A Follow-on Production Contract Or Ot For Production To Participants In The Ot For Prototype Projects Without The Use Of Further Competitive Procedures, If The Participant In The Ot For Prototype Projects Successfully Completes The Prototype Project, As Permitted By 10 Usc 4022(f). 5.1.1 Iterative Prototyping a Contract Or Ot For A Prototype Awarded Under This Cso Shall Allow For An Iterative Prototyping Process. An Iterative Prototyping Process Will Allow The Government To Modify, By Mutual Agreement, The Scope Of A Prototype Contract Or Ot To Allow For The Adaptation And Modification Of The Technology Being Prototyped To Meet Additional Unique And Discrete Purposes/mission Sets. The Sequential Prototype Iterations May Result In A Separate Prototype Project Rather Than A Modification Of The Original Prototype Contract Or Ot. These Additional Unique And Discrete Purposes/mission Sets Can Be Generated By Aflcmc Or Originate Within Any Organization That Aflcmc Supports. 5.1.2 Successful Completion Of A Prototype a Prototype Project Is Complete Upon The Written Determination Of The Appropriate Approving Official (program Manager And Contracting/agreements Officer) For The Matter In Question That The Efforts Conducted Under A Prototype Contract Or Ot: (1) Met The Key Technical Goals Of A Project; (2) Met The Metrics Incorporated Into The Prototype Contract Or Ot; Or (3) Accomplished A Particularly Favorable Or Unexpected Result That Justifies The Transition To A Production Contract Or Ot. Furthermore, Prior To Successful Completion Of A Prototype Project Under This Cso, The Government Can Transition Any Aspect Of The Prototype Project Determined To Provide Utility Into Production While Other Aspects Of The Prototype Project Have Yet To Be Completed. 5.1.3 Follow-on Production Of A Prototype after Award Of A Prototype Using Ot Authority, The Government And Vendor May Negotiate A Follow-on Contract Or Ot For Production Or Solution Integration With Or Without Further Competition. Any Concept/technology/solution Successfully Proven Through A Prototype Ot Can Be Transitioned To A Production Contract. The Government Reserves The Right To Award A Follow-on Contract Or Ot Before The Prototype Is Compete, Under Competitive Procedures As Provided In 10 U.s.c. 4022. any Call Posted By The Government Under This Cso Could Result In The Potential Award Of A Follow-on Production Or Solution Integration Contract Or Ot. the Government Reserves The Right To Extend The Performance To All, Some Or None Of The Selected Solutions And Decisions Will Be Made Based On The Availability Of Government Funds. 5.2 Other Transaction Agreements (otas) Specifics in Accordance With 10 U.s.c. 4022(c), If An Agreement For A Prototype Is Utilized And If That Agreement Provides For Payments In A Total Amount In Excess Of $5m, The Agreement Will Include A Mandatory Clause That Provides For The Comptroller General The Ability To Examine The Records Of Any Party To The Agreement Or Any Entity That Participates In The Performance Of The Agreement. The $5m Amount Includes The Base Agreement Plus Any Options. additionally, To Enter Into An Ot For A Prototype Agreement Under 10 U.s.c. 4022, One Of The Following Conditions Must Be Met: there Is At Least One Nontraditional Defense Contractor Or Nonprofit Research Institution Participating To A Significant Extent In The Prototype Project. all Significant Participants Other Than The Federal Government Are Small Business Concerns Or Nontraditional Defense Contractors. parties To The Transaction Other Than The Federal Government Must Pay At Least One Third Of The Prototype Total Cost. the Senior Procurement Executive Determines That Exceptional Circumstances Justify The Use Of An Ot To Provide An Innovative Business Arrangement Not Feasible Under A Contract Or To Expand The Defense Supply Base In A Manner Not Practical Under A Contract. all Otas Awarded Under This Cso Will Contain Prohibitions On The Use Of Certain Telecommunications Devices In Accordance With Dfars 52.204-25. Further Specifics And Requirements As It Relates To Ots May Be Applicable And Included In Subsequent Calls Published Under This Cso. 6.0 Closed Calls this Cso Will Have Close Calls That Consist Of Either A One-step Or Two-step Process, Which Will Be Specified In Each Individual Call. For A One-step Call, Only Proposals Will Be Solicited. For A Two-step Call, White Papers Will Be Solicited First And Then, Consistent With This Section, Subsequent Requests For Proposals May Follow After The Government Reviews The White Paper. any Part Of This Process May Be Modified Or Altered By Aflcmc In The Calls Or Through An Amendment To This Cso. It Is Important To Note That At No Stage Is Aflcmc Obligated To Make Any Awards And All Awards Are Subject To The Availability Of Funds And Successful Negotiations. The Government Is Not Responsible For Any Monies Expended By Vendors Prior To The Issuance Of Any Contract/agreement Award. 6.1 One-step Closed Call Process 6.1.1 Call Published aflcmc Intends On Publishing A Call Via An Amendment To This Cso. The Call Will Specifically State The Cso Call Type (closed, One-step). This Call Will Provide A Required Date And Time For Submission Of The Proposal. The Call Would Also Detail The Specific Areas Of Interest Being Solicited For, Required Proposal Content, Evaluation Criteria And Detailed Requirements Unique To That Particular Call. 6.1.2 Proposals Received proposals That Are Received On Time Will Be Evaluated Consistent With The Evaluation Criteria Identified Within The Call. After This Technical Review Is Complete, Aflcmc Will Notify Each Prospective Vendor As To Whether Their Proposal Was Selected To Proceed To The Contract Negotiations And Fact-finding Stage. 6.1.3 Contract Negotiations And Fact Finding if A Vendor Is Notified That It Has Been Selected To Proceed To The Next Stage, Then Contract Negotiations And Fact-finding Will Occur. This Includes Contract Formation, Scope, Cost/price And Any Other Terms And Conditions The Contracting/agreements Officer Requires Discussion. It Is Important To Note That At This Stage Aflcmc Is Not Required To Make An Award, Which Is Expressly Contingent Upon Successful Negotiation Of Cost/price, Terms And Conditions And The Availability Of Funds. 6.1.4 Award Decision after Contract Negotiations And Fact-finding Are Complete, Aflcmc Will Render A Decision(s) Whether Or Not To Enter Into A Contract/agreement With The Prospective Vendor. 6.2 Two-step Closed Call Process 6.2.1 Call Published aflcmc Would Publish A Call Via An Amendment To This Cso. The Call Would Specifically State That The Cso Call Type Is A Two-step, Closed Call. This Call Will Provide A Specific State And Time When Prospective Vendors May Submit Their White Papers. The Call Would Also Detail The Specific Areas Of Interest Being Solicited For, Required White Paper Content, Evaluation Criteria And Details Any Other Requirements Unique To That Particular Call. 6.2.2 White Papers Received aflcmc Will Review Submitted White Papers In Accordance With The Evaluation Criteria Specified In The Call. If A Vendor’s White Paper Is Evaluated Favorably By Aflcmc, The Government Will Send Initially Selected Vendors A Request For Proposal (rfp). Invited Vendors Will Proceed To Preparing And Submitting A Proposal For Evaluation. Additional Details Will Be Included Within The Rfp. 6.2.3 Incorporate Sections 6.1.2-6.1.4 after The Submission Of The White Papers And Issuance Of Rfps To Favorably Evaluated White Papers, The Remaining Process Is The Same As The One-step, Closed Call. Therefore, Sections 6.1.2, 6.1.3 And 6.1.4 Are Hereby Incorporated By Reference. 7.0 Open Period Calls this Cso May Have Open Period Calls That Consist Only Of A Two-step Process. For This Call Type, The Process Will Mirror The Process Articulated In 6.2 Above; However, With The Important Distinction That White Papers Will Be Accepted At Any Time During The Stated Time Period On The Call. This Is In Contrast To A Closed Call Where All Proposals Are Required To Be Submitted At A Specific Date And Time Together And Follow A Standard Timeline For All Participants. For Open Period Calls, The Timelines Are Usually Less Structured And Broader In Nature. Typical Turn-around Times That Vendors Can Expect Are Usually Stated In The Call. Aflcmc Reserves The Right To Modify Or Alter Any Of These Instructions In Each Individual Call. 8.0 Evaluation Criteria the Evaluation Criteria For White Papers And Proposals Will Be Explicitly Detailed In Each Individual Call. Solutions Will Be Evaluated On The Basis Of The Merit Of The Proposed Concept In Addressing The Areas Of Interest And Not Against Other Vendor’s Solution Briefs Submitted In Response To The Same Area Of Interest. disclaimer: No Proposals Or White Papers Are Being Requested At This Time. Those Will Be Requested Via Calls Published Under The Cso Solicitation. 9.0 General Proposal Information 9.1 Proposal Content below Is The Typical Structure And Required Volumes For Proposal Submission. Aflcmc Reserves The Right To Alter Or Change The Structure And Required Content For Each Proposal Submission As Specified In A Particular Call. title Page (does Not Count Against Page Limit) Including Company Name, Cage Number (if Applicable), Title, Point Of Contact Name, Date, Email, Address, Phone, Organization/office Symbol (if Applicable). Identify If You Or A Proposed Subcontractor Are A Small Business Such As 8(a), Small, Disadvantaged Business, Woman-owned Business, Hubzoned Small Business, Veteran-owned Business, Service Disabled Veteran Owned Business, Historically Black College Of University And Minority Institution. Identification Of Potential Sponsor(s) Organizations. volume 1: Technical Volume: This Will Typically Contain A Page Limit And Require Specific Technical Details The Government Requires All Prospective Vendors To Address. volume 2: Cost Volume: This Section Is Where Vendors Shall Detail The Proposed Cost By Breaking Down The Overall Proposed Price Into Specific Cost Categories (ex. Direct Labor, Overhead, Direct Materials, Other Direct Costs, Profit). The Government Reserves The Right To Specify A Cost Volume Format In Any Particular Call. 9.2 Proprietary Information information Constituting A Trade Secret, Commercial Or Financial Information, Confidential Personal Information, Or Data Affecting National Security Must Be Clearly Marked. It Shall Be Treated In Confidence To The Extent Permitted By Law. This Restriction Does Not Limit The Government’s Right To Use Information Contained If It Is Obtained From Another Source Without Restriction. Aflcmc Assumes No Liability For Disclosure Or Use Of Unmarked Data And May Use Or Disclose Such Data For Any Purpose. If A Vendor Is Awarded A Contract As A Result Of Or In Connection With The Submission Of Proprietary Data In The Proposal, The Government Shall Have The Right To Duplicate, Use Or Disclose The Data To The Extent Provided In The Resulting Contract/agreement. proposals Containing Data That Is Not To Be Disclosed To The Public For Any Purpose Or Used By The Government Except For Evaluation Purposes Shall Include The Following Sentences In Accordance With Far 52.215-1(e)(1) And (2) On The Cover Page: “this Proposal Includes Data That Shall Not Be Disclosed Outside The Government And Shall Not Be Duplicated, Used, Or Disclosed—in Whole Or In Part – For Any Purpose Other Than To Evaluate This Proposal. If, However, A Contract Is Awarded To This Offeror As A Result Of – Or In Connection With – The Submission Of This Data, The Government Shall Have The Right To Duplicate, Use, Or Disclose The Data To The Extend Provided In The Resulting Contract. This Restriction Does Not Limit The Government’s Right To Use Information Contained In This Data If It Is Obtained From Another Source Without Restriction. The Data Subject To This Restriction Are Contain In Sheets [insert Numbers Or Other Identification Of Sheets].” each Restricted Data Sheet Should Be Marked As Follows: use Or Disclose Of Data Contained On This Sheet Is Subject To The Restriction On The Title Page Of This Proposal. 9.3 Classified Proposals classified Whitepapers/proposals Will Not Be Accepted Under This Cso Unless Otherwise Stated In The Call. If Topics Require Classified Work, The Proposing Vendor Must Have A Facility Clearance In Order To Perform The Work. 9.4 Security security Classification Will Be Determined For Each Call/award. If Classified Data Will Be Accessed Or Generated, A Facility And Storage Clearance, At The Required Classification Level, Will Be Required And The Proposal Will Discuss Appropriate Personnel And Facility Clearances. if A Vendor Has Any Reason To Believe Their Concept May Reference Ideas Or Operations That Require Special Protection, The Vendor Should Immediately Contact The Contracting/agreements Officer For Further Instruction. additionally, If A Dd254 Is Applicable For A Call/award, Vendors Must Verify Their Cognizant Security Office Information Is Current With Defense Security Service (dss). 9.5 Promotional Material promotional And Non-project Related Discussion Is Discouraged, And Additional Information Provided Via Universal Resource Locator (url) Links Or On Computer Disks, Cds, Dvds, Video Tapes Or Any Other Medium Will Not Be Accepted Or Considered In The Proposal Evaluation Unless Otherwise Directed By The Call Or The Contracting/agreements Officer. This Also Means That Unnecessarily Elaborate Brochures Or Proposals Are Not Desired. 9.6 Small Business far-based Contracts Awarded Pursuant To This Cso Shall Include Far 52.219-8, Utilization Of Small Business Concerns (oct 2018). Far-based Contract Awarded Pursuant To This Cso Which Meet Far Subpart 19.7 Criteria For Small Business Subcontracting Plans Shall Include Far 52.219-9, Small Business Subcontracting Plan (march 2020). vendors Shall Address Plans To Comply With These Requirements As Part Of Their Proposals If Seeking Ots Which Provide For Follow-on Non-competitive Production Contracts. Vendors Not Seeking Either Instrument In The Preceding Sentence Shall Clearly State So As Part Of Their Proposal And Shall Address These Requirements As Part Of The Competition For Follow-on Production Contracts. In The Event That Any Follow-up Production Contracts Are Required To Have Small Business Subcontracting Plans And Are Negotiated Using Far 15, Dfars 215.304(c) Small Business Participation Plan Shall Be Required. 9.7 Export-controlled Items depending On The Proposal, It May Be Subject To Export Control (international Traffic In Arms (itar) 22 Cfr 120-131, Or Export Administration Regulations (ear) 15 Cfr 710-774). If The Effort Is Subject To Export Controls, Then A Certified Dd Form 2345, Military Critical Technical Data Agreement, Will Be Required To Be Submitted With Proposals. Dfars 252.225-7048, “export Controlled Item (jun 2013)” Clause Shall Be Contained In All Resulting Contracts. 9.8 Data Rights all Proposal Submissions Shall Include Data Rights Assertions, If Applicable. This Will Be An Essential Element Of Each Proposal Submission. aflcmc Reserves The Right To Negotiate Data Rights As Part Of The Contracting/agreement Process. Additionally, Each Call May Have Specific Data Rights Considerations Associated With It. Should This Be The Case, The Specific Rights Aflcmc Is Requesting Will Be Detailed In Each Call. Aflcmc Also Reserves The Right To Tailor The Data Management Approach For Each Individual Effort Based On The Needs For Each Situation. 9.8.1 Far Part 12 Considerations in Accordance With Dfars 227.7102-1, Aflcmc Seeks To Acquire The Technical Data That Is Customarily Available On A Commercial Basis. As A Result, Dfars Clauses 252.227-7015 And 252.227-7037 Will Be Included On Each Far Part 12 Contract Awarded As A Result Of This Cso Or Any Of Its Calls. If Additional Data Rights Are Considered Warranted, Aflcmc Reserves The Right To Negotiate These With Prospective Vendors As Part Of The Contracting Process. if The Government Pays For Any Portion Of The Development Costs, Dfars 252.227-7013 Will Be Included To Govern The Associated Technical Data For The Portion Of The Commercial Items That Was Developed Using Government Funds. For The Portion Of Commercial Items That Was Developed Exclusively At Private Expense, Dfars 252.227-7015 Will Still Govern The Technical Data To The Extent Is Commercial. companies Whose Effort Originated Under The Sbir Program Will Maintain Standard Sbir Data Rights In Accordance With Dfars 252.227-7018 (class Deviation 2020-o0007). additional Clauses May Be Applicable Depending On The Technology And Requirements Associated With It. 10.0 Other Information 10.1 Unique Item Identification for Hardware Deliverables, Item Unique Identification In Accordance With Dfars 252.211-7003 May Be Required. Vendors May Contact The Contracting/agreements Officer For Additional Information. 10.2 Foreign-owned Businesses foreign-owned Businesses May Independently Submit A Solution Or Do So As Part Of A Teaming Agreement With One Or More United States-owned Businesses. However, The Ability To Obtain A Contract/agreement Based Upon A Submission May Depend Upon The Ability For The Foreign-owned Business To Obtain Necessary Clearances And Approvals To Obtain Prescribed Information. 10.3 Within Scope Modifications potential Vendors Are Advised That Awards Resulting From The Calls Under This Cso May Be Modified During The Performance To Make Within Scope Changes. Only A Contracting/agreements Officer Can Legally Bind A Contract/agreement Modification On Behalf Of The United States Government. 10.4 Non-government Advisors And Source Selection Information non-government Advisors May Participate In The Evaluation Of All Submissions And Shall Have A Signed Non-disclosure Agreement (nda) With The Government. Non-governmental Advisors May Also Serve In Administrative And Assistance Support Capacities. The Government Understands That Information Provided In Response To This Cso Is Presented In Confidence And May Contain Trade Secrets Or Commercial Or Financial Information, And It Agrees To Protect Such Information From Unauthorized Disclosure To The Maximum Extent Permitted Or Required By Law. aflcmc Will Treat All Submissions To Calls Published Against This Cso As Source Selection Information. During The Evaluation Process, Submissions May Be Handled By Non-government Advisors For Administrative Purposes And/or Technical Evaluations. All Government Support Contractors Are Bound By Appropriate Ndas. Submissions Will Not Be Returned Unless Otherwise Stated In The Call. 10.5 Multiple White Paper/proposal Submissions vendors May Submit Multiple Submissions In Response To Any Single Area Of Interest Detailed In Each Call If Each Submission Represents A Separate And Distinct Concept. However, For Each Individual Submission, Prospective Vendors May Only Address One Distinct Technical Solution Per Submission Unless Otherwise Permitted In The Individual Call. 10.6 Fraud And False Statements knowingly And Willfully Making False, Fictitious, Or Fraudulent Statements Or Representations May Be A Felony Under The Federal Criminal False Statement Act (18 U.s.c. 1001) Punishable By A Fine Or Up To $10,000, Up To Five Years In Prison, Or Both. 10.7 Duns And Sam Registration vendors Must Have A Unique Entity Identifier (uei) And Must Register In The System For Award Management (sam) Prior To Receiving An Award Or Agreement. Vendors Must Not Be Suspended Or Debarred From Award By The Federal Government Nor Be Prohibited By Presidential Executive Order And/or Law From Receiving An Award. 10.8 Wawf Registration as Specified In A Particular Call, Vendors May Be Required To Be Registered In The Prescribed Government Invoicing System (wide Area Work Flow). If Not Specified, The Call Will Explain How Invoicing Will Be Handled. 10.9 Supplier Performance Risk System (sprs) in Order To Receive A Dod Contract, Every Vendor Will Be Required To Perform A Basis Nist Sp 800-171 Dod Assessment. That Process Is Described Here. once The Basic Nist 800-171 Dod Assessment Is Complete, Each Contractor Will Need To Follow The Instructions Here To Enter The Results In Sprp On The Piee Website. 10.10 Cost Sharing Or Matching cost Sharing Or Matching Will Be Considered Based On The Solutions Proposed And Details Associated With Each Call. Aflcmc Has Final Decision Authority On Whether To Enter Into A Cost Sharing Or Matching Agreement.