Security Services Tenders

Details: This Is A Sources Sought Notice. This Is Not A Solicitation For Proposals, Proposal Abstracts, Or Quotations. The Purpose Of This Notice Is To Obtain Information Regarding The Availability And Capability Of All Qualified Sources To Perform A Potential Requirement. this Notice Is Issued To Help Determine The Availability Of Qualified Companies Technically Capable Of Meeting The Government Requirement And To Determine The Method Of Acquisition. It Is Not To Be Construed As A Commitment By The Government To Issue A Solicitation Or Ultimately Award A Contract. Responses Will Not Be Considered As Proposals Or Quotes. No Award Will Be Made As A Result Of This Notice. The Government Will Not Be Responsible For Any Costs Incurred By The Respondents To This Notice. This Notice Is Strictly For Research And Information Purposes Only. the Government Is Especially Interested In Determining (1) The Availability Of Qualified Small Business Sources; (2) Whether They Are Small Businesses; Hubzone Small Businesses; Service-disabled, Veteran-owned Small Businesses; 8(a) Small Businesses; Veteran-owned Small Businesses; Woman-owned Small Businesses; Or Small Disadvantaged Businesses; And (3) Their Size Classification Relative To The North American Industry Classification System (naics) Code For The Proposed Acquisition. Your Responses To The Information Requested Will Assist The Government In Determining The Appropriate Acquisition Method, Including Whether A Set-aside Is Possible. background: the Therapeutic Development Branch (tdb) Within The Division Of Preclinical Innovation (dpi) At National Center For Advancing Translational Sciences (ncats), National Institutes Of Health (nih) Conducts Translational Research In The Area Of Human Therapeutics Development By Moving Small Molecule And Biologic Drug Candidates Forward In The Drug Development Pipeline. Upon Reaching Predetermined Milestones, Tdb Hands Off Clinical Candidates To External Partners To Bring These Novel Therapies To Patients. In Addition To Developing New Candidate Drugs, Tdb Seeks To Advance The Entire Field Of Drug Discovery And Development By Encouraging Scientific And Technological Innovations Aimed At Improving Success Rates In The Crucial Preclinical Stage Of Drug Development. The Tdb Model Is To Operate As A Comprehensive Small Molecule And Biologics Drug Development Organization, Moving Therapeutic Candidates Through Each Phase Of The Preclinical Development Process Until An Investigational New Drug (ind) Application Is Filed With The Us Food And Drug Administration (fda). Tdb Conducts Drug Development As Collaborations, With Therapeutic Candidates Originating From Academia, Industry, Non- Profit Foundations, Or Internally From Ncats And Other Nih Institutes And Centers. Tdb’s Operational Strategy Is To Combine The Capabilities Of In-house Staff And Collaborative Partners With Complementary Support From Contract Research Organizations (cros). Each Development Program Operates In A Multi-disciplinary Matrix Team Environment, With Ncats Responsible For The Overall Planning And Execution. project Requirements: contract Administration the Contractor Shall Perform Activities Related To The Overall Administration Of The Contract. This Includes Fulfilling Administrative Reporting And Deliverable Requirements, Ensuring Contract Terms And Conditions Are Adhered To, And Communicating With The Contracting Officer’s Representative (cor) And Contracting Officer (co) As Needed. project Management the Contractor Shall Provide Project Management For Their Own Core Team To Ensure Effective Project Planning, Execution, Delivery Of Reports, And Accurate And Timely Communication With The Cor, Co, And Other Stakeholders. The Contractor Shall Provide And Implement Overall Project Management To Coordinate And Integrate Activities For Each Task Order. The Contractor Shall Provide Sufficient Project Management Staff To Ensure Management And Monitoring Of All Task Order Activities And Shall Identify For Each Task Order A Lead Individual Who Will Serve As A Primary Point Of Contact For The Government. the Contractor Shall Provide Qualified Multidisciplinary Staff To Fulfill The Requirements Of Each Task Order Award. For Each Discipline, The Staff Shall Have All The Required And Customary Training, Experience, And Licensure Or Certification Needed To Fulfill Their Assigned Role. collaboration And Communications the Contractor Shall Provide Effective Collaboration And Communication With The Cor, Co, And Other Stakeholders As Needed To Support Successful Task Order Performance And Project Outcomes. This Includes Providing Status Updates And Technical Information When Requested And Providing Information As Needed To Ensure The Government Is Sufficiently Informed In Accordance With The Needs Of The Project. This Also Includes Collaboration On Deliverables, Technical Approaches, Or Other Areas. the Contractor Shall Participate In Regularly-scheduled And Ad Hoc Meetings With The Government And Other Stakeholders As Needed. The Contractor Will Generally Be Required To Provide Meeting Support Such As Logistics And Arrangements, Facilitation, Graphics And Video Support, Materials Preparation And Distribution, And Translation, As Well As Meeting Notes, Minutes, Summaries And/or Summary Reports. Such Meetings May Include: task Order Initiation / Kick-off Meetings. These Meetings Are To Review The Applicable Requirements And Timelines, Discuss Technical Plans/project Management Plan And Approaches, And Identify Any Anticipated Problems/obstacles To Completing The Requirements. progress Review Meetings. These Meetings Are To Review And Discuss Ongoing And Planned Activities, Protocols And Associated Data; Timelines For Task Initiation And Completion, Submission Of Data And Other Information; Any Problems Or Deficiencies Identified With Respect To The Accuracy, Timeliness, And Completeness Of Research, Trials And Studies, Including Outcomes Such As Data Submission; And Any Other Matters Relevant To The Task Order Performance Or Administration. ad Hoc Meetings. These Meetings May Be Required To Address Issues Or Questions That Arise Related To Performance Or Administration. They May Also Include Investigator, Protocol, Working Group, Strategic Planning, And Network Meetings. quality Management the Contractor Shall Ensure That All Work Performed Under This Contract, Including By Any Subcontractors, Meets The Highest Levels Of Quality, As Appropriate For The Task. All Management And Operational Systems Used Must Be Sufficient To Monitor, Maintain, And Document Quality. one Or More Domestic Or International Regulations May Apply To Task Orders Issued Under This Idiq. These Include, But Are Not Limited To, Us Fda Current Good Manufacturing Practice (cgmp), Good Laboratory Practice (glp) And Good Clinical Practice (gcp) Regulations, And/or International Council For Harmonisation (ich) And International Organization For Standardization (iso) Regulations. When One Or More Regulations Apply, The Contractor Shall: provide A Quality Assurance Unit (qau) That Is Independent Of Other Operations Of The Contractor To Assure That All Products And Services Meet Quality Requirements And Comply With International, Federal, State And Local Government Regulations, As Applicable. provide A Quality Assurance/quality Control (qa/qc) Infrastructure For The Awarded Contract Including Sops For Establishing And Maintaining The Qa/qc Processes And Approaches/methods To Document, Identify The Source(s) Of And Address Any Problems And Deviations As They Occur, As Well As Provide Recommendations For The Resolution Of Problems And Correction Of Deviations. The Contractor Shall Have A Quality Management Plan (qmp) That Shall Include Management Responsibilities, Resources, Assessment And Training, Oversight Of Outsourced Operations, Defined Metrics, And Accountability For Identification And Remediation Of Errors As Well As Communication Processes And Timelines. arrange And/or Accommodate Independent Audits Of Any Contractor Or Subcontractor Sites. The Government May Require An Independent Audit Of Any Contractor And/or Subcontractor Sites To Ensure That All Facilities Satisfy The Quality Requirements Set Forth For Successful Performance Of The Work. During Such An Audit, The Contractor Shall Ensure That Staff, Facilities, And Relevant Documentation Are Available. The Contractor Shall Prepare Updates To The Qmp And Provide Updated Plans Including Corrective Actions And Preventative Actions (capa) As Needed. facilities, Equipment, And Other Resource Management the Contractor Shall Provide And Maintain Facilities, Equipment, Space, And Other Resources As Needed That Comply With All Local, Domestic, In-country, State, Federal And Nih Regulations. The Contractor Shall Maintain Qa Documentation To Support Adherence To These Areas. This Includes Submitting A Floor Plan Of The Relevant Facilities And Providing Safe And Secure Operation Of / Access To Those Facilities; Establishing Processes And Procedures Limiting Access To Only Approved And Qualified Staff To Physical Sites, Systems, Equipment, Technology, Internet, And/or Data; And Providing Biohazard, Environmental And Occupational Health Safety, Emergency Management/preparedness, Security, Transportation And Logistics Services. All Work With Hazardous Biological Materials Shall Comply With All Local, Domestic, In-country, State, Federal And Nih Regulations. Contingency And Catastrophic Event Plans Shall Be Developed And Documented To Protect Project-related Work. the Contractor Shall Provide For Overall Management And Conduct Of The Receipt, Storage, Retrieval, Custom Clearance, Packaging And Shipping Of Materials, Including Obtaining Appropriate Licenses And Permits And Developing Sops For Processes And Procedures. All Storage, Packaging, And Shipping Shall Comply With All Local Laws And All Applicable Regulations. As Appropriate, Material Shall Be Inventoried And Tracked To Ensure Chain Of Custody. Plans Shall Be Developed And Documented To Identify And Mitigate Against Supply Chain Or Other Delays To Ensure Steady Access To Critical Resources. data Access And Technology Transfer the Contractor Shall Fully Support Submission Of Technology Transfer Packages To The Government Or A Designated Third Party When Directed By The Cor And/or At The Completion Of The Task Order. Technology Transfer Packages Will Include Information, Technology, And Documentation Created With Sufficient Detail, Clarity, And Completeness To Enable The Receiving Party To Fully Understand, And If Needed, Repeat Activities Of The Task Order. In Certain Cases, The Contractor May Be Required To Provide Training To The Government Or Designated Third Parties To Utilize Or Operate A Subject Technology. The Contractor Will Support Ncats Regulatory Affairs Processes By Providing Authorization To The Government And/or Any Relevant Third Parties Identified By The Government To Access And Cross Reference Relevant Prior Data Generated By The Contractor, Including But Not Limited To, Drug Master Files (dmfs) Or Other Previous Regulatory Filings, As Needed. site Visits the Contractor Shall Arrange And/or Accommodate Site Visits And Independent Audits As Needed. Site Visits May Be Necessary To Ensure That All Required Equipment Is Available And In Good Working Order And To Review The Training Records Of All Key Technical Staff, As Available. Audits May Be Needed To Assure Contractor And Subcontractor Facilities And All Planned Procedures Meet Regulatory (e.g., Gmp, Glp) Or Other Quality Control Standards. The Contractor Shall Ensure All Contractor And Subcontractor Records And Staff Are Available In Response To Site Visits Or Study-specific Audits, And Provide Interim And Final Audit Reports To The Cor. All Data Generated By The Contractor To Support Manufacture Of Cgmp Material Shall Have A Strict Quality System Review Of Raw Data And Transcription, Technical Supervisor Approval, And Quality Assurance (qa) Release. project Closeout the Contractor Shall Ensure An Orderly, Secure, And Efficient Transition At The Conclusion Of Each Task Order. This May Include Preparing And Submitting A Transition Plan; Transferring And/or Disposing Of Contract-related Materials, Supplies, And Information / Data; And Retaining Documents In Secure Storage (up To Five Years). research Involving Animals this Sow Involves The Use Of Live Vertebrate Animals. All Work Involving Live Vertebrate Animals Shall Be Conducted In Accordance With The Terms And Conditions Of The Idiq Contract. technical Requirements independently And Not As An Agent Of The Government, The Contractor Shall Be Required To Furnish All The Necessary Services, Qualified Personnel, Materials, Equipment, And Facilities Not Otherwise Provided By The Government To Provide The Services Described In This Statement Of Work And Subsequent Task Orders. reagent Generation the Contractor Shall Generate And Deliver Reagents That Support The Development Of Methods For Quantification Of Novel Biologic Drugs In Plasma/serum, Tissue Homogenates, And Other Biological Matrices. These Reagents Will Comprise Anti-drug Antibodies (adas) With High Affinity And Specificity For A Biologic Drug Of Interest, Including Adas With Neutralizing Activity (neutralizing Antibodies, Nabs) Against The Active Epitope Of The Biologic Drug Of Interest. For Gene-based Therapies, This Includes Antibodies Against The Gene-of-interest (goi) Protein Product And The Carriers (e.g., Vector Capsids), Including Those That May Neutralize The Vector-mediated Delivery Of A Goi. the Contractor May Be Required To: (1) Deliver Multiple Reagents Under A Single Task Order If A Single Reagent Does Not Meet All The Specific Criteria; (2) Undertake More Than One Immunization Strategy Or Antibody Library Screening Per Task Order To Assure The Generation Of One Or More Appropriate Bioanalytical Reagents; And (3) Screen Relevant Commercially Available Antibodies As An Initial Step In Task Order Performance. anticipated Activities Under A Task Order Include, But Are Not Limited To: generating Polyclonal Anti-drug Antibodies (adas). generating Monoclonal Adas. characterizing The Specificity Of The Generated Adas, Including Their Reactivity Towards Drug-specific Active Epitopes (nabs). producing Purified Antibodies Suitable As Reagents For Bioanalytical Method Development And Testing (estimated 10 – 50 Mg Scale Per Reagent). capability Statement /information Sought. Respondents Must Be Registered In The System For Award Management (sam), And Address The Following Questions: provide Your Duns Number, Organization Name, Address, And Point Of Contact. If Your Business Is A Small Business, Include Your Size And Type Of Business (e.g., 8(a), Hubzone, Etc., Sdvosb, Etc.) Pursuant To The Applicable Naics Code provide A Capability Statement That Addresses The Project Requirements Listed Above, With Particular Attention To The Description Of Your Commercial Solution And General Estimates Regarding The Length Of Time Required To Implement The Solution. provide Any Other Information That May Be Helpful In Developing Or Finalizing The Acquisition Requirements. the Information Submitted Must Be In And Outline Format That Addresses Each Of The Elements Of The Project Requirement And In The Capability Statement /information Sought Paragraphs Stated Herein. A Cover Page And An Executive Summary May Be Included But Is Not Required. the Response Must Include The Respondents’ Technical And Administrative Points Of Contact, Including Names, Titles, Addresses, Telephone Numbers, And E-mail Addresses. all Responses To This Notice Must Be Submitted By Email To Nick Niefeld, Contract Specialist, At Nick.niefeld@nih.gov, And Reference Sources Sought Notice Number 75n95025r00007. the Response Must Be Received On Or Before Friday, November 8, 2024 At 11:00 A.m. Eastern Time. disclaimer And Important Notes: This Notice Does Not Obligate The Government To Award A Contract Or Otherwise Pay For The Information Provided In Response. The Government Reserves The Right To Use Information Provided By Respondents For Any Purpose Deemed Necessary And Legally Appropriate. Any Organization Responding To This Notice Should Ensure That Its Response Is Complete And Sufficiently Detailed To Allow The Government To Determine The Organization’s Qualifications To Perform The Work. respondents Are Advised That The Government Is Under No Obligation To Acknowledge Receipt Of The Information Received Or Provide Feedback To Respondents With Respect To Any Information Submitted. After A Review Of The Responses Received, A Synopsis And Solicitation May Be Published In Sam.gov Contract Opportunities. However, Responses To This Notice Will Not Be Considered Adequate Responses To A Solicitation. confidentiality: No Proprietary, Classified, Confidential, Or Sensitive Information Should Be Included In Your Response. The Government Reserves The Right To Use Any Non-proprietary Technical Information In Any Resultant Solicitation(s).

Details: This Is A Sources Sought Notice. This Is Not A Solicitation For Proposals, Proposal Abstracts, Or Quotations. The Purpose Of This Notice Is To Obtain Information Regarding The Availability And Capability Of All Qualified Sources To Perform A Potential Requirement. this Notice Is Issued To Help Determine The Availability Of Qualified Companies Technically Capable Of Meeting The Government Requirement And To Determine The Method Of Acquisition. It Is Not To Be Construed As A Commitment By The Government To Issue A Solicitation Or Ultimately Award A Contract. Responses Will Not Be Considered As Proposals Or Quotes. No Award Will Be Made As A Result Of This Notice. The Government Will Not Be Responsible For Any Costs Incurred By The Respondents To This Notice. This Notice Is Strictly For Research And Information Purposes Only. the Government Is Especially Interested In Determining (1) The Availability Of Qualified Small Business Sources; (2) Whether They Are Small Businesses; Hubzone Small Businesses; Service-disabled, Veteran-owned Small Businesses; 8(a) Small Businesses; Veteran-owned Small Businesses; Woman-owned Small Businesses; Or Small Disadvantaged Businesses; And (3) Their Size Classification Relative To The North American Industry Classification System (naics) Code For The Proposed Acquisition. Your Responses To The Information Requested Will Assist The Government In Determining The Appropriate Acquisition Method, Including Whether A Set-aside Is Possible. background: the Therapeutic Development Branch (tdb) Within The Division Of Preclinical Innovation (dpi) At National Center For Advancing Translational Sciences (ncats), National Institutes Of Health (nih) Conducts Translational Research In The Area Of Human Therapeutics Development By Moving Small Molecule And Biologic Drug Candidates Forward In The Drug Development Pipeline. Upon Reaching Predetermined Milestones, Tdb Hands Off Clinical Candidates To External Partners To Bring These Novel Therapies To Patients. In Addition To Developing New Candidate Drugs, Tdb Seeks To Advance The Entire Field Of Drug Discovery And Development By Encouraging Scientific And Technological Innovations Aimed At Improving Success Rates In The Crucial Preclinical Stage Of Drug Development. The Tdb Model Is To Operate As A Comprehensive Small Molecule And Biologics Drug Development Organization, Moving Therapeutic Candidates Through Each Phase Of The Preclinical Development Process Until An Investigational New Drug (ind) Application Is Filed With The Us Food And Drug Administration (fda). Tdb Conducts Drug Development As Collaborations, With Therapeutic Candidates Originating From Academia, Industry, Non- Profit Foundations, Or Internally From Ncats And Other Nih Institutes. Tdb’s Operational Strategy Is To Combine The Capabilities Of In-house Staff And Collaborative Partners With Complementary Support From Contract Research Organizations (cros). Each Development Program Operates In A Multi-disciplinary Matrix Team Environment, With Ncats Responsible For The Overall Planning And Execution. project Requirements: contract Administration the Contractor Shall Perform Activities Related To The Overall Administration Of The Contract. This Includes Fulfilling Administrative Reporting And Deliverable Requirements, Ensuring Contract Terms And Conditions Are Adhered To, And Communicating With The Contracting Officer’s Representative (cor) And Contracting Officer (co) As Needed. project Management the Contractor Shall Provide Project Management For Its Own Core Team To Ensure Effective Project Planning, Execution, Delivery Of Reports, And Accurate And Timely Communication With The Cor, Co, And Other Stakeholders. The Contractor Shall Provide And Implement Overall Project Management To Coordinate And Integrate Activities For Each Task Order. The Contractor Shall Provide Sufficient Project Management Staff To Ensure Management And Monitoring Of All Task Order Activities And Shall Identify For Each Task Order A Lead Individual Who Will Serve As A Primary Point Of Contact For The Government. the Contractor Shall Provide Qualified Multidisciplinary Staff To Fulfill The Requirements Of Each Task Order Award. For Each Discipline, The Staff Shall Have All The Required And Customary Training, Experience, And Licensure Or Certification Needed To Fulfill Their Assigned Role. collaboration And Communications the Contractor Shall Provide Effective Collaboration And Communication With The Cor, Co, And Other Stakeholders As Needed To Support Successful Task Order Performance And Project Outcomes. This Includes Providing Status Updates And Technical Information When Requested And Providing Information As Needed To Ensure The Government Is Sufficiently Informed In Accordance With The Needs Of The Project. This Also Includes Collaboration On Deliverables, Technical Approaches, Or Other Areas. the Contractor Shall Participate In Regularly-scheduled And Ad Hoc Meetings With The Government And Other Stakeholders As Needed. The Contractor Will Generally Be Required To Provide Meeting Support Such As Logistics And Arrangements, Facilitation, Graphics And Video Support, Materials Preparation And Distribution, And Translation, As Well As Meeting Notes, Minutes, Summaries And/or Summary Reports. Such Meetings May Include: task Order Initiation / Kick-off Meetings. These Meetings Are To Review The Applicable Requirements And Timelines, Discuss Technical Plans/project Management Plan And Approaches, And Identify Any Anticipated Problems/obstacles To Completing The Requirements. progress Review Meetings. These Meetings Are To Review And Discuss Ongoing And Planned Activities, Protocols And Associated Data; Timelines For Task Initiation And Completion, Submission Of Data And Other Information; Any Problems Or Deficiencies Identified With Respect To The Accuracy, Timeliness, And Completeness Of Research, Trials And Studies, Including Outcomes Such As Data Submission; And Any Other Matters Relevant To The Task Order Performance Or Administration. ad Hoc Meetings. These Meetings May Be Required To Address Issues Or Questions That Arise Related To Performance Or Administration. They May Also Include Investigator, Protocol, Working Group, Strategic Planning, And Network Meetings. quality Management the Contractor Shall Ensure That All Work Performed Under This Contract, Including By Any Subcontractors, Meets The Highest Levels Of Quality, As Appropriate For The Task. All Management And Operational Systems Used Must Be Sufficient To Monitor, Maintain, And Document Quality. one Or More Domestic Or International Regulations May Apply To Task Orders Issued Under This Idiq. These Include, But Are Not Limited To, Us Fda Current Good Manufacturing Practice (cgmp), Good Laboratory Practice (glp) And Good Clinical Practice (gcp) Regulations, And/or International Council For Harmonisation (ich) And International Organization For Standardization (iso) Regulations. When One Or More Regulations Apply, The Contractor Shall: provide A Quality Assurance Unit (qau) That Is Independent Of Other Operations Of The Contractor To Assure That All Products And Services Meet Quality Requirements And Comply With International, Federal, State And Local Government Regulations, As Applicable. provide A Quality Assurance/quality Control (qa/qc) Infrastructure For The Awarded Contract Including Sops For Establishing And Maintaining The Qa/qc Processes And Approaches/methods To Document, Identify The Source(s) Of And Address Any Problems And Deviations As They Occur, As Well As Provide Recommendations For The Resolution Of Problems And Correction Of Deviations. The Contractor Shall Have A Quality Management Plan (qmp) That Shall Include Management Responsibilities, Resources, Assessment And Training, Oversight Of Outsourced Operations, Defined Metrics, And Accountability For Identification And Remediation Of Errors As Well As Communication Processes And Timelines. arrange And/or Accommodate Independent Audits Of Any Contractor Or Subcontractor Sites. The Government May Require An Independent Audit Of Any Contractor And/or Subcontractor Sites To Ensure That All Facilities Satisfy The Quality Requirements Set Forth For Successful Performance Of The Work. During Such An Audit, The Contractor Shall Ensure That Staff, Facilities, And Relevant Documentation Are Available. The Contractor Shall Prepare Updates To The Qmp And Provide Updated Plans Including Corrective Actions And Preventative Actions (capa) As Needed. facilities, Equipment And Other Resource Management the Contractor Shall Provide And Maintain Facilities, Equipment, Space, And Other Resources As Needed That Comply With All Local, Domestic, In-country, State, Federal And Nih Regulations. The Contractor Shall Maintain Qa Documentation To Support Adherence To These Areas. This Includes Submitting A Floor Plan Of The Relevant Facilities And Providing Safe And Secure Operation Of /access To Those Facilities; Establishing Processes And Procedures Limiting Access To Only Approved And Qualified Staff To Physical Sites, Systems, Equipment, Technology, Internet, And/or Data; And Providing Biohazard, Environmental And Occupational Health Safety, Emergency Management/preparedness, Security, Transportation And Logistics Services. All Work With Hazardous Biological Materials Shall Comply With All Local, Domestic, In-country, State, Federal And Nih Regulations. Contingency And Catastrophic Event Plans Shall Be Developed And Documented To Protect Project-related Work. the Contractor Shall Provide For Overall Management And Conduct Of The Receipt, Storage, Retrieval, Custom Clearance, Packaging And Shipping Of Materials, Including Obtaining Appropriate Licenses And Permits And Developing Sops For Processes And Procedures. All Storage, Packaging, And Shipping Shall Comply With All Local Laws And All Applicable Regulations. As Appropriate, Material Shall Be Inventoried And Tracked To Ensure Chain Of Custody. Plans Shall Be Developed And Documented To Identify And Mitigate Against Supply Chain Or Other Delays To Ensure Steady Access To Critical Resources. data Access And Technology Transfer the Contractor Shall Fully Support Submission Of Technology Transfer Packages To The Government Or A Designated Third Party When Directed By The Cor And/or At The Completion Of The Task Order. Technology Transfer Packages Will Include Information, Technology, And Documentation Created With Sufficient Detail, Clarity, And Completeness To Enable The Receiving Party To Fully Understand, And If Needed, Repeat Activities Of The Task Order. In Certain Cases, The Contractor May Be Required To Provide Training To The Government Or Designated Third Parties To Utilize Or Operate A Subject Technology. The Contractor Will Support Ncats Regulatory Affairs Processes By Providing Authorization To The Government And/or Any Relevant Third Parties Identified By The Government To Access And Cross Reference Relevant Prior Data Generated By The Contractor, Including But Not Limited To, Drug Master Files (dmfs) Or Other Previous Regulatory Filings, As Needed. site Visits the Contractor Shall Arrange And/or Accommodate Site Visits And Independent Audits As Needed. Site Visits May Be Necessary To Ensure That All Required Equipment Is Available And In Good Working Order And To Review The Training Records Of All Key Technical Staff, As Available. Audits May Be Needed To Assure Contractor And Subcontractor Facilities And All Planned Procedures Meet Regulatory (e.g., Gmp, Glp) Or Other Quality Control Standards. The Contractor Shall Ensure All Contractor And Subcontractor Records And Staff Are Available In Response To Site Visits Or Study-specific Audits, And Provide Interim And Final Audit Reports To The Cor. All Data Generated By The Contractor To Support Manufacture Of Cgmp Material Shall Have A Strict Quality System Review Of Raw Data And Transcription, Technical Supervisor Approval, And Quality Assurance (qa) Release. project Closeout the Contractor Shall Ensure An Orderly, Secure, And Efficient Transition At The Conclusion Of Each Task Order. This May Include Preparing And Submitting A Transition Plan; Transferring And/or Disposing Of Contract-related Materials, Supplies, And Information / Data; And Retaining Documents In Secure Storage (up To Five Years). technical Requirements independently And Not As An Agent Of The Government, The Contractor Shall Be Required To Furnish All The Necessary Services, Qualified Personnel, Materials, Equipment, And Facilities Not Otherwise Provided By The Government To Provide The Services Described In This Statement Of Work And Subsequent Task Orders. area 1: Bioanalytical Method Development For Novel Biologic Drugs the Contractor Shall: (1) Develop And/or Qualify Bioanalytical Methods For Quantitative Analyses Of Novel Therapeutic Biologics In Plasma/serum, Tissue Homogenates, And Other Biological Fluids From Animal Species Used In Efficacy And Toxicity Studies (e.g., Mice, Rats, Dogs, And Monkeys) And From Human Clinical Trials; And (2) Develop Assays To Measure Anti-drug Antibodies (adas), Including Neutralizing Antibodies (nabs), And To Assess Treatment-emergent Cytokine-secreting Immune Cells In Rodent And Non-rodent Animal Species And Humans. For Gene-based Therapies, This Includes Developing Methods To Assess Antibodies Against The Carriers (e.g., Vector Capsids) And The Gene-of-interest (goi) Protein Product. The Contractor Will Not Be Responsible For Obtaining Clinical Samples From Patients Directly, And All Clinical Samples Will Be Deidentified Prior To Being Sent To The Contractor. anticipated Activities Include, But Are Not Limited To: develop Robust (accurate, Precise, Specific/selective And Reproducible) Methods To Detect The Relevant Attribute (e.g., Biologic Drug, Anti-drug Antibodies) At A Wide Range Of Concentrations. Standard Curves Should Contain A Minimum Of Six Non-zero Concentration Points. Cell-based Assays Are The Government’s Preferred Format For Detection Of Neutralizing Antibodies (nabs). verify Or Validate Methods For Appropriate Accuracy And Precision, Specificity And Selectivity Using Low, Medium And High Concentration Quality Control (qc) Samples. Assays Must Be Suitable For Measurement Of A Novel Biologic Drug And Any Adas, Including Nabs, In Concentration Ranges Expected To Be Present In Study Samples. perform Method Characterization Studies To Define The Stability Of Representative Samples Under Various Storage And Handling Conditions (e.g., Room Temperature, Multiple Freeze/thaw Cycles, And Long-term Storage At -20°c Or -80°c). determine The Stability Of A Novel Biologic Drug In Blood/plasma/serum, Tissues Or Other Biologic Fluids To Guide Sample Collection Processes In Animal Studies Or Clinical Trials. provide Instructions On Precaution(s) Or Method(s) Necessary To Prevent Degradation Of A Novel Biologic Drug In Blood/plasma/serum, Tissues Or Other Biologic Fluids During Sample Handling. assess The Extraction Efficiency Of An Assay In The Biologic Matrices Of Interest, Which May Include The Utilization Of A Radiolabeled Biologic. establish Cut-points For Distinguishing Positive Control (pc) And Negative Control (nc) Samples. include Screening, Confirmatory/specificity, And Titer Components In The Clinical Assay For Detection Of Adas, Including Nabs. the Contractor Shall Deliver Assay Development Plans, Development Reports (outlining Experiments Conducted In The Development Phase), Validation Plans, And Validation Reports. These Reports And Plans Must Be Reviewed And Approved By The Cor. The Contractor May Not Proceed To Subsequent Phases Until Approval Is Received From The Cor (e.g., A Validation Protocol Must Be Approved Before The Validation Run May Commence). area 2: Bioanalysis Of Novel Biologic Drugs In Biologic Matrices the Contractor Shall Provide Bioanalytical Support For Biologic Drug Concentration And Anti-drug Antibody (ada) Measurement, Including Neutralizing Antibodies (nabs), For Samples Collected From Animal Pharmacokinetic And Efficacy Studies As Well As From Human Clinical Trials. The Contractor Will Not Be Responsible For Obtaining Clinical Samples From Patients Directly, And All Clinical Samples Will Be Deidentified Prior To Being Sent To The Contractor. the Assays Used May Be Developed By The Contractor Or Transferred To The Contractor From A Third Party. All Assays Used Should Be Validated In Accordance With Current Regulatory Guidelines And Expectations. The Contractor Shall Document Any Assay Deviations From The Validated Methods To Support The Precision And Accuracy Of Measurements Established With The Quality Control Samples. The Contractor Shall Perform Incurred Sample Re-analysis (isr) On Samples Derived From Glp Toxicology And/or Clinical Studies. upon Completion Of An Assay, The Contractor Shall Deliver Bioanalytical Reports For Drug And Anti-drug Antibody (ada) Concentrations In Biologic Matrices. These Documents Must Be Reviewed And Approved By The Cor. The Contractor Shall Clearly Document Sample Receiving Conditions, Sample Id, And Sample Storage Conditions And Duration Needs. for Toxicokinetics (tk) In Glp Toxicity Studies And Pharmacokinetics (pk) In Human Clinical Trials, The Contractor Shall Calculate Important Tk/pk Parameters, Which Include, But Are Not Limited To, Area Under The Concentration-time Curve (auc), Maximum Drug Concentration (cmax), Time To Reach Cmax (tmax), Clearance, Half-life (t1/2), Volume Of Distribution, And Bioavailability. Furthermore, The Contractor Shall Calculate And Report Tk/pk Parameters For Each Individual Subject, When Possible, And The Standard Deviation For Each Treatment Group. The Contractor Shall Use Fda-approved Software For Such Analyses Using The Non-compartmental Approach. The Government Recommends Validated Phoenix Winnonlin Software (certara, Radnor, Pa). the Contractor Shall Provide Bioanalytical Reports For Clinical Samples, And Shall Clearly Document Sample Receiving Conditions, Sample Id, And Sample Storage Conditions And Duration Needs. capability Statement /information Sought. Respondents Must Be Registered In The System For Award Management (sam), And Address The Following Questions: provide Your Duns Number, Organization Name, Address, And Point Of Contact. If Your Business Is A Small Business, Include Your Size And Type Of Business (e.g., 8(a), Hubzone, Etc., Sdvosb, Etc.) Pursuant To The Applicable Naics Code provide A Capability Statement That Addresses The Project Requirements Listed Above, With Particular Attention To The Description Of Your Commercial Solution And General Estimates Regarding The Length Of Time Required To Implement The Solution. provide Any Other Information That May Be Helpful In Developing Or Finalizing The Acquisition Requirements. the Information Submitted Must Be In And Outline Format That Addresses Each Of The Elements Of The Project Requirement And In The Capability Statement /information Sought Paragraphs Stated Herein. A Cover Page And An Executive Summary May Be Included But Is Not Required. the Response Must Include The Respondents’ Technical And Administrative Points Of Contact, Including Names, Titles, Addresses, Telephone Numbers, And E-mail Addresses. all Responses To This Notice Must Be Submitted By Email To Nick Niefeld, Contract Specialist, At Nick.niefeld@nih.gov, And Reference Sources Sought Notice Number 75n95025r00006. the Response Must Be Received On Or Before Friday, November 8, 2024 At 11:00 A.m. Eastern Time. disclaimer And Important Notes: This Notice Does Not Obligate The Government To Award A Contract Or Otherwise Pay For The Information Provided In Response. The Government Reserves The Right To Use Information Provided By Respondents For Any Purpose Deemed Necessary And Legally Appropriate. Any Organization Responding To This Notice Should Ensure That Its Response Is Complete And Sufficiently Detailed To Allow The Government To Determine The Organization’s Qualifications To Perform The Work. respondents Are Advised That The Government Is Under No Obligation To Acknowledge Receipt Of The Information Received Or Provide Feedback To Respondents With Respect To Any Information Submitted. After A Review Of The Responses Received, A Synopsis And Solicitation May Be Published In Sam.gov Contract Opportunities. However, Responses To This Notice Will Not Be Considered Adequate Responses To A Solicitation. confidentiality: No Proprietary, Classified, Confidential, Or Sensitive Information Should Be Included In Your Response. The Government Reserves The Right To Use Any Non-proprietary Technical Information In Any Resultant Solicitation(s).

Details: Chemistry, Manufacturing And Controls And Related Services For Development Of Drug Products classification Code/title: An12 - Health R&d Services; Health Care Services; Applied Research naics Code/title: 325412 – Pharmaceutical Preparation Manufacturing related Notice: Presolicitation Notice Id Ps75n95023r00037, Chemistry Manufacturing And Controls And Related Services For Drug Products, Published May 30, 2023. purpose Of Notice: This Is A Research And Development (r&d) Small Business Sources Sought Notice. This Is Not A Solicitation For Proposals, Proposal Abstracts, Or Quotations. The Purpose Of This Notice Is To Obtain Information Regarding The Availability And Capability Of Small Business Sources To Perform A Potential R & D Requirement. the Purpose Of This Notice Is To Obtain Information Regarding: (1) The Availability And Capability Of Qualified Small Business Sources; (2) Whether They Are Small Businesses; Hubzone Small Businesses; Service-disabled, Veteran-owned Small Businesses; 8(a) Small Businesses; Veteran-owned Small Businesses; Woman-owned Small Businesses; Or Small Disadvantaged Businesses; And (3) Their Size Classification Relative To The North American Industry Classification System (naics) Code For The Proposed Acquisition. your Responses To The Information Requested Will Assist The Government In Determining The Appropriate Acquisition Method, Including Whether A Set-aside Is Possible. An Organization That Is Not Considered A Small Business Under The Applicable Naics Code Should Not Submit A Response To This Notice. this Notice Is Issued To Help Determine The Availability Of Qualified Companies Technically Capable Of Meeting The Government Requirement And To Determine The Method Of Acquisition. It Is Not To Be Construed As A Commitment By The Government To Issue A Solicitation Or Ultimately Award A Contract. Responses Will Not Be Considered As Proposals Or Quotes. No Award Will Be Made As A Result Of This Notice. The Government Will Not Be Responsible For Any Costs Incurred By The Respondents To This Notice. This Notice Is Strictly For Research And Information Purposes Only. The Government Will Not Entertain Questions Regarding The Results Of This Market Research. background: The Therapeutic Development Branch (tdb) Within The Division Of Preclinical Innovation (dpi) At The National Center For Advancing Translational Sciences (ncats) Within The National Institutes Of Health (nih) Conducts Translational Research To Support Therapeutic Development By Moving Small Molecule And Biologic Drug Candidates Forward In The Drug Development Pipeline. Upon Reaching Predetermined Milestones, Tdb Hands Off Clinical Candidates To External Partners To Bring These Novel Therapies To Patients. In Addition To Developing New Candidate Drugs, Tdb Seeks To Advance The Entire Field Of Drug Discovery And Development By Encouraging Scientific And Technological Innovations Aimed At Improving Success Rates In The Crucial Preclinical Stage Of Drug Development. The Tdb Model Is To Operate As A Comprehensive Small Molecule And Biologics Drug Development Organization, Moving Therapeutic Candidates Through Each Phase Of The Preclinical Development Process Until An Investigational New Drug (ind) Application Is Filed With The Us Food And Drug Administration (fda). For Certain Drug Development Campaigns, Tdb Will Support Studies Up To Human Phase Iib. Tdb Conducts Drug Development Through Collaborations, With Therapeutic Candidates Originating From Academia, Industry, Non-profit Foundations, Or Internally From Ncats And Other Nih Institutes. Tdb's Operational Strategy Is To Combine The Capabilities Of In-house Staff And Collaborative Partners With Complementary Support From Contract Research Organizations (cros). Each Development Program Operates In A Multi-disciplinary Matrix Team Environment, With Ncats Responsible For Overall Planning And Execution. the Scope Of This Requirement Is Chemistry, Manufacturing, And Controls And Related Services For Development Of Drug Products. The Objective Of These Support Services Is To Ensure Receipt Of Drug Products (dp) Of Sufficient Quality And Quantity To Support Preclinical, Ind-enabling And Clinical Studies. the Ncats Has An Existing Multiple-award Idiq Contract For Drug Product Development And Manufacture. This Potential Procurement Would Be A Re-competition (ramp-on) Of This Existing Contract. purpose And Objectives: The Purpose Of This Small Business Sources Sought Is To Obtain Information About Small Business Capabilities To Support The Dpi Drug Development Programs By Providing Chemistry, Manufacturing, And Controls (cmc) Services; Provide Support For A Broad Range Of Preclinical Services Required For The Design, Development, Manufacture, And Release Of Dp As Clinical Trial Material (ctm), Including Precursors, Preliminary States, Reference Standards (rs) And All Required Testing. Ancillary Products (e.g., Placebos, Diluents, Adjuvants, Master Cell Banks, Testing Standards, Reference Materials) And Other Materials Manufactured Or Purchased To Support Clinical Trials Or Cmc Activities May Also Be Required. All Activities Preliminary To Manufacturing In Accordance With Current Good Manufacturing Practice (cgmp) May Be Required (e.g., Development Or Engineering Lots, Formulation Studies), Even Without An Associated Cgmp Manufacturing Task. All Activities Required To Maintain Material In A Usable State, Including Storage, Shipping, Testing (in Process, Release, Stability, And Quality Actions), And Preparation Of Documents To Support Regulatory Submissions May Also Be Required. product Formats May Include Small Molecules, Short Oligomeric Compounds, Biological (large) Molecules, Quaternary Molecular Assemblies (homogenous Or Heterogenous), Vectors For Gene Therapy, Nanoparticles, And Any Of The Above Modified Genetically, Biologically, Or Chemically. Novel Formats Identified After This Draft Might Also Be Needed. Formats Could Also Include Devices Or Combination Products. project Requirements: The Potential Acquisition Is Anticipated To Be A Multiple-award Indefinite Delivery / Indefinite Quantity (idiq) Contract For Chemistry, Manufacturing, And Controls And Related Services For Development Of Drug Products. The Current Idiq Contract(s) Has Three Separate Technical Areas: Technical Area 1: Formulation Development, Manufacture And Analysis Of Small Molecule Drug Products; Technical Area 2: Formulation Development, Manufacture And Analysis Of Synthetic Peptides, Oligonucleotides, And Related Substances; And Technical Area 3: Formulation Development, Manufacture And Analysis Of Biopharmaceutical And Gene Therapy Drug Products. The Anticipated Idiq Contract(s) May Be Awarded Under One Or More Technical Areas. the Contractor Shall Be Compliant With Applicable Domestic Or International Regulations. These May Include, But Are Not Limited To, One Or More Of The Following: Us Fda Current Good Manufacturing Practice (cgmp), Good Laboratory Practice (glp) And Good Clinical Practice (gcp) Regulations, And/or International Council For Harmonisation (ich) And International Organization For Standardization (iso) Regulations. the Contractor Shall Provide Biohazard, Environmental And Occupational Health Safety, Emergency Management/preparedness, Security, Transportation And Logistics Services. All Work With Hazardous Biological Materials Shall Comply With All Applicable Regulations. anticipated Period Of Performance: The Idiq Contract(s) Currently Have A Seven-year Ordering Period. Task Orders Issued Under The Idiq Contract(s) Will Have A Shorter Period Of Performance. It Is Estimated That The Remaining Ordering Period Will Be Approximately Six Years. information Requested: Vendors Should Provide A Capability Statement That Addresses Their Capability And Experience In One Or More Of The Below Technical Areas. Vendors May Provide A Capability Statement In One Area, Two Areas, Or All Three Areas. Vendors With Prior, Similar Experience Should Clearly Demonstrate That Experience And Include Information On The Size And Scope Of That Experience. If Prior Experience Was Gained With The Government As A Prime Or Subcontractor, Describe The Size And Scope Of The Work And Provide The Contract Number. capability Statements Should Address Each Point Listed Under The Applicable Technical Area(s). Capability Statements Must Address The Specific Technical Area(s) And Points In This Notice; General Capability Statements Will Not Be Reviewed. vendors Seeking To Respond To This Notice As Part Of A Teaming Arrangement Should Include The Requested Information From Each Vendor In The Proposed Team. technical Area 1: Formulation Development, Manufacture And Analysis Of Small Molecule Drug Products i. The Contractor Shall Perform Activities Related To The Formulation Development, Manufacture And Analysis Of Small Molecule Drug Products. ii. Anticipated Activities Related To The Formulation Development And Manufacture Of Small Molecule Drug Product Include, But Are Not Limited To, The Following: a. Perform Technology Transfer From The Government Or Its Collaborators, And Route Familiarization. b. Perform Formulation Development Studies And Define Final Formulation. c. Perform Pre-formulation Studies Based On The Targeted Dosage Form. d. Conduct Formulation Development Studies Based On The Targeted Dosage Form. e. Determine Critical/key Process Parameters And Optimize Final Formulation Using Design Of Experiments (doe) f. Perform Process Demonstration Runs. g. Perform Cost Analysis. h. Manufacture Non-gmp Dp Of Sufficient Quality And In Quantities Necessary To Meet The Needs Of Preclinical Studies, Typically 500 To 5,000 Units. i. Manufacture Dp Under Cgmp, Of Sufficient Quality And In Quantities To Support Clinical Studies, Typically 1,000 To 10,000 Units. iii. Anticipated Activities Related To The Analysis Of Small Molecule Drug Products Include, But Are Not Limited To, The Following: a. Develop Necessary In Process Control (ipc) Methods For Manufacture Of Dp. b. Validate Analytical And Stability-indicating, Dosage-specific Analytical Methods (e.g., Dissolution Method For Capsule Dosage Form). c. Identify, Isolate, And Characterize Impurities And Degradation Products. d. Develop Release Specifications. e. Perform All Tests Necessary To Release Dp For Clinical Use, Including Issuing A Certificate Of Analysis (coa). f. Establish Stability Protocols With Proper Specifications For Dp And Perform Stability Studies Up To 24 Months (minimum) Per Guidelines Published By The International Council For Harmonisation Of Technical Requirements For Pharmaceuticals For Human Use (ich). g. Perform Clinical Simulation Studies Of The Intended Administration Of Dp To Humans. iv. Anticipated Activities Considered Ancillary To The Formulation Development, Manufacture And Analysis Of Small Molecule Drug Products Include, But Are Not Limited To, The Following: a. Deliver Study Reports, Including But Not Limited To Weekly Status Update Reports, Summary Development Reports, Analytical Methods Development And Qualification/validation Protocols And Reports, Master Batch Report, Gmp Campaign Report, And Cmc Report In The Common Technical Document (ctd) Format Utilized For Regulatory Submissions To The Fda. b. Conduct Bi-weekly Or Weekly (as Required) Project Update Teleconferences. c. Perform Technology Transfer From/to A Third Party When Required. d. Store Non-gmp And Gmp Lots Of Reference Standard (rs), Drug Substance (ds) And Dp. e. Ensure Compliance With Cgmp. f. Maintain Quality Systems To Support Cgmp Activities. g. Provide Quarterly Cost Schedule And Performance Reports. technical Area 2: Formulation Development, Manufacture And Analysis Of Synthetic Peptides, Oligonucleotides, And Related Drug Products i. The Contractor Shall Perform Activities Related To The Formulation Development, Manufacture And Analysis Of Synthetic Peptides, Oligonucleotides, And Related Drug Products. ii. Anticipated Activities Related To The Formulation Development And Manufacture Of Synthetic Peptides, Oligonucleotides, And Related Substances Include, But Are Not Limited To, The Following: a. Perform Technology Transfer From The Government Or Its Collaborators, And Route Familiarization. b. Perform Pre-formulation Studies Based On The Targeted Dosage Form. c. Conduct Formulation Development Studies Based On The Targeted Dosage Form. d. Perform Formulation Development Studies And Define Final Formulation. e. Determine Critical/key Process Parameters And Optimize Final Formulation Using Design Of Experiments (doe) f. Perform Process Demonstration Runs. g. Perform Cost Analysis. h. Manufacture Non-gmp Dp Of Sufficient Quality And In Quantities Necessary To Meet The Needs Of Preclinical Studies, Typically 500 To 5,000 Units. i. Manufacture Dp Under Cgmp, Of Sufficient Quality And In Quantities To Support Clinical Studies, Typically 1,000 To 10,000 Units. iii. Anticipated Activities Related To The Analysis Of Synthetic Peptides, Oligonucleotides, And Related Substances Include, But Are Not Limited To, The Following: a. Validate Analytical And Stability-indicating Methods. b. Perform Forced Degradation Studies. c. Identify, Isolate, And Characterize Impurities And Degradation Products. d. Develop Release Specifications. e. Perform All Tests Necessary To Release Dp For Clinical Use, Including Issuing A Coa. f. Establish Stability Protocols With Proper Specifications For Dp And Perform Stability Studies Up To 24 Months (minimum) Per Ich Guidelines. g. Perform Clinical Simulation Studies Of The Intended Administration Of Dp To Humans. iv. Anticipated Activities Considered Ancillary To The Manufacture And Analysis Of Synthetic Peptides, Oligonucleotides, And Related Substances Include, But Are Not Limited To, The Following: a. Deliver Study Reports, Including But Not Limited To Weekly Status Update Reports, Summary Development Reports, Analytical Methods Development And Qualification/validation Protocols And Reports, Forced Degradation Study Protocols And Reports, Master Batch Reports, Gmp Campaign Reports, And Cmc Report In Ctd Format. b. Conduct Bi-weekly Or Weekly (as Required) Project Update Teleconferences. c. Perform Technology Transfer From/to A Third Party When Required. d. Store Non-gmp And Gmp Lots Of Rs, Ds And Dp. e. Ensure Compliance With Cgmp. f. Maintain Quality Systems To Support Cgmp Activities. technical Area 3: Formulation Development, Manufacture And Analysis Of Biopharmaceutical And Gene Therapy Drug Products i. The Contractor Shall Perform Activities Related To The Formulation Development, Manufacture And Analysis Of Biopharmaceutical And Gene Therapy Drug Products. ii. Anticipated Activities Related To The Manufacture And Analysis Of Biopharmaceuticals And Gene Therapies Include, But Are Not Limited To, The Following: a. Analytical Method Development: o Develop, Qualify And/or Validate Analytical Methods, Per Ich Guidelines. o Perform Characterization Of Drug Substance (ds) And Drug Product (dp) For Identity, Content, Purity, Potency And Safety. o Develop Release Specifications. b. Formulation Development Studies: o Perform Excipient Screening, Optimize, And Develop Final Formulation Buffer For Liquid Formulation And Lyophilization Protocol For Lyophilized Dp. o Perform Accelerated Stability Studies. o Define Container Closure And Fill Finish Strategy. c. Manufacturing Under Current Good Manufacturing Practices (cgmp): o Manufacture Master Cell Banks And Perform Cryo-storage (expected To Be Not Less Than 300 Vials Per Candidate). o Conduct Viral Clearance Validation Studies. o Manufacture Cgmp Lots Of Dp (including Fill Finish, In Amounts Determined Per To) To Support Clinical Studies, Typically 1,000 To 10,000 Units. o Perform All Tests Necessary To Release Dp For Clinical Use, Including Issuing A Coa. o Perform Stability Evaluation Of Dp, Per Ich Guidelines. iii. Anticipated Activities Considered Ancillary To The Manufacture And Analysis Of Biopharmaceuticals And Gene Therapies Include, But Are Not Limited To, The Following: a. Deliver Study Reports, Including But Not Limited To Weekly Status Update Reports, Summary Development Reports, Analytical Methods Development And Qualification/validation Reports, Executed Cgmp Batch Records, A Cmc Report In Ctd Format. b. Conduct Bi-weekly Or Weekly (as Required) Project Update Teleconferences. c. Perform Technology Transfer From/to A Third Party When Required. d. Store Non-gmp And Gmp Lots Of Rs, Ds And Dp. e. Ensure Compliance With Cgmp. f. Maintain Quality Systems To Support Cgmp Activities. response Instructions: Responses Are Required No Later Than 10:00am Eastern Time On July 21, 2024. Responses Must Be Submitted Via Email To Michelle.cecilia@nih.gov And Should Include The Following: a. Capability Statement That Addresses One Or More Technical Areas And The Overall Technical Requirements As Applied To Each Technical Area In The Capability Statement. b. Cover Page That Includes The Following: • Duns • Company Name • Company Address • Company Point Of Contact, Phone, And Email Address • Naics Code Under Which The Company Conducts Business As A Small Business • Company Size / Socio Economic Status (e.g., Small Business, 8(a), Woman Owned, Veteran, Etc.) - Validated Via Sam • State Whether Your Organization Uses Any Proprietary Technology For Any Of The Activities Described For Technical Areas 1, 2, Or 3. If So, Clarify Whether Ncats And Ncats’ Collaborators Will Have Freedom To Use The Technology At A Third-party Facility In The Event The Project Is Later Transferred To A Third Party. • State Whether There Are Any Classes Of Scheduled Compounds Or Hazardous Reagents / Reactions Your Organization Is Unable To Handle Due To Regulation Or Safety Limitations. • Acknowledgment Of Compliance With Far Clause 52.219-14. As Noted Below, Far Clause 52.219-14 Will Apply To Any Portion Of The Acquisition That Is Set Aside For Small Business. Respondents Must Acknowledge They Will Comply With This Clause If They Are Awarded An Idiq Contract Under A Set-aside. Respondents Who Fail To Acknowledge This Will Be Deemed Not Capable For The Purposes Of This Small Business Sources Sought. disclaimer And Important Notes: This Notice Does Not Obligate The Government To Award A Contract Or Otherwise Pay For The Information Provided In Response. The Government Reserves The Right To Use Information Provided By Respondents For Any Purpose Deemed Necessary And Legally Appropriate. Any Organization Responding To This Notice Should Ensure That Its Response Is Complete And Sufficiently Detailed To Allow The Government To Determine The Organization’s Qualifications To Perform The Work. respondents Are Advised That The Government Is Under No Obligation To Acknowledge Receipt Of The Information Received Or Provide Feedback To Respondents With Respect To Any Information Submitted. After A Review Of The Responses Received, A Pre-solicitation Synopsis And Solicitation May Be Published In Sam. However, Responses To This Notice Will Not Be Considered Adequate Responses To A Solicitation. if Any Portion Of The Potential Acquisition Is Set Aside For Small Business, Far Clause 52.219-14, Limitations On Subcontracting, Will Apply To The Portion That Is Set Aside. This Clause States The Prime Small Business Contractor Cannot Subcontract More Than 50% Of The Work To A Non-similarly Situated Entity. The Full Text Of The Clause Is Available At Https://www.acquisition.gov/far/part-52#far_52_219_14. to Enable Contributors To Retain Control Of The Intellectual Property For Compounds Created Under The Anticipated Idiq Contracts, The Government Has An Executed Declaration Of Exceptional Circumstances (dec) To The Federal Acquisition Regulations (far) For This Program. confidentiality: No Proprietary, Classified, Confidential, Or Sensitive Information Should Be Included In Your Response. The Government Reserves The Right To Use Any Non-proprietary Technical Information In Any Resultant Solicitation(s).

Details: Description Project Title : Repair/renovation Of Doña Felomina Building Location : Devmh Compound, Bood, Ubay, Bohol Estimated Project Cost : Php 10,000,000.00 Terms Of Reference Summary Of Works A. General Requirements I. Mobilization/demobilization • The Work Consists Of The Mobilization And Demobilization Of The Contractor’s Forces And Equipment Necessary For Performing The Work Required Under The Contract. Ii. Permits And Licenses • Process And Submit Electrical Design Review Including Sign And Seal Of Electrical Plans, Electrical Review, Analysis, Computations And Signature Of Pee On Electrical Plans And Including All Forms And Plans For The Application Of Permit To Construct (ptc) For Doh Licensing. Design And Analysis Should Be Submitted Prior To Commencement Of Civil Works. Iii. Temporary Facilities • Temporary Facilities Shall Be Provided During The Construction Period And Will Be Constructed Within The Hospital Compound, Which Shall Serve As The Field Office, Storage Of Materials And Bunkhouse For The Workers. The Contractor Shall Provide And Maintain Temporary Power & Lighting, Temporary Water Service & Security Within The Construction Site. Iv. Health, Safety & Environment Control (complete Ppe, Safety Equipment & Devices & Safety Accessories And Signages) • Safety/warning Signage Must Be Placed By The Contractor On The Construction Area With Clear Demarcation Of Construction Zones To Prevent Unauthorized Access. • Detours And Closures: Provide Directions For Alternate Routes And Notice Of Any Closed Areas. • Hazard Notifications: Provide Signs Indicating Potential Dangers In Construction Areas (e.g., "hard Hat Area," "no Entry"). • Emergency Information: Clear Guidance On Emergency Exits And Procedures During Construction. • Fall Protection: Always Use Safety Harnesses And Guardrails. • Weather Conditions: Avoid Dismantling In High Winds, Rain, Or Extreme Temperatures. • Team Communication: Maintain Clear Communication Among Team Members And Healthcare Facility Engineering Team To Coordinate Movements And Tasks. V. As-built (record) Drawings & Related Documents • Submit One (1) Completed Set Of Signed And Sealed As-built Plans (whiteprint Copy) • Submit One (1) Set Of Electronic Files Of Signed And Sealed As-built Plans (cadd Editable File) • The Drawings Shall Be Supplemented With Descriptive Specification As Appropriate To Clearly Record The Exact Form And Content Of Work Described In This Specification And On The Drawings. • Maintain A Complete And Accurate Record Of All Changes Or Deviations To The Contract Documents And Shop Drawings In The Trade Contractor’s Field Office. Such Record Copy Shall Indicate The Work As Actually Constructed And Be Available For Hospital Appointed Engineer To Review. • Incorporate All Minor Revisions And Clarifications Noted Thru The Field Modification Process Which May Not Necessarily Be Shown On The Architectural Drawings Or Issued As Addenda, Bulletins, Or Change Orders. • Field Changes Shall Be Neatly And Correctly Shown On One Set Of Record Prints On A Daily Basis By The Foreman, Or Superintendent Of Are Each Trade; And This Set Will Act As A Record Set At Completion Of The Work And Is Intended To Be Of Assistance To The Trade Contractor In Preparing Record Documents. Vi. Material Sustainability • The Contractor Shall Use At Least Ten Percent (10%) Locally Manufactured Materials For The Project. Submit Purchase Order And Other Supporting Documents As Evidence. • The Contractor Shall Avoid Using Building Materials/products That Contain Toxic Chemicals Or Use Materials That Are Low In Volatile Organic Compound. Please Refer To The Following • Materials Specification As Stated On This Terms Of Reference. • The Contractor Shall Only Used Light Bulbs And Electrical Devices With More Efficient Models And Type As Specified On Approved And Signed Bill Of Quantities (e.g. Led Bulbs). Submit Purchase Order And Other Supporting Documents As Evidence. • The Contractor Shall Conform To The Following Painting And Other Wet Applied Materials (such As Coatings, Sealants) Requirements: 1. Only Qualified Products With Mpi "environmentally Friendly" E1 E2 E3 Rating Will Be Used. Paints, Coatings, Thinners, Solvents, Cleaners And Other Fluids Used In Repainting, Shall:  Not Contain Methylene Chloride, Chlorinated Hydrocarbons, Toxic Metal Pigments.  Be Manufactured Without Compounds Which Contribute To Ozone Depletion In The Upper Atmosphere.  Be Manufactured Without Compounds Which Contribute To Smog In The Lower Atmosphere. Be Manufactured In A Manner Where Matter Generating A 'biochemical Oxygen Demand' (bod) In Undiluted Production Plant Effluent Discharged To A Natural Watercourse Or A Sewage Treatment Facility Lacking Secondary Treatment Does Not Exceed 15 Mg/l.  Be Manufactured In A Manner Where The Total Suspended Solids (tss) Content In Undiluted Production Plant Effluent Discharged To A Natural Watercourse Or A Sewage Treatment Facility Lacking Secondary Treatment Does Not Exceed 15 Mg/l. 2. Paints And Coatings Must Be Manufactured And Transported In A Manner That Steps Of Processes, Including Disposal Of Waste Products Arising There From, Will Meet Requirements Of Applicable Governmental Acts, By-laws And Regulations In The Philippines. 3. Paints And Coatings Must Not Be Formulated Or Manufactured With Formaldehyde, Halogenated Solvents, Mercury, Lead, Cadmium, Hexavalent Chromium Or Their Compounds. Eco Labeled. 4. Anti-corrosive Coatings: Provide A Certification By The Manufacturer That Products Supplied Comply With The Volatile Organic Compound (voc) And Chemical Component Restrictions Of Green Seal Environmental Standard Gc-03, If The Product Is An Anti-corrosive Coating Applied Indoors And On-site. 5. Other Interior Coatings: If The Product Is Applied Indoors And On-site, And Not Covered By Both The Green Seal Environmental Standard Gs-11 And Standard Gc-03, Provide A Certification By The Manufacturer That Products Supplied Comply With The Chemical Component Restrictions Of The Green Seal Environmental Standard Gs-11, Paints, And Comply With The Volatile Organic Compound (voc) Restrictions Of The State Of California Air Resources Board (carb) Suggested Control Measure For Architectural Coatings, And The South Coast Air Quality Management District Rule 1113: Architectural Coatings B. Civil Works I. Site Works • The Contractor Shall Be Responsible In Setting Out Reference Lines, Elevations (lines And Grades) Prior And During The Execution Of The Works. All References Shall Be Maintained And Protected By The Contractor At His Own Expense. Disturbed References Shall Be Restored To Its Original Position Without Extra Cost To The Healthcare Facility. • Work Includes But Is Not Limited To:  Demolition/clearing Works For Ceiling  Demolition/clearing Works For Concrete Walls  Chipping Of Existing Tile Setting Ii. Structural & Concrete Works (refer Applicable Sections On Chapter 4 Of The Nscp, For Quality Of Materials, Workmanship, Execution, Acceptance, Etc.) Iii.1. General • Provide All Labor, Materials, Equipment, Transportation, And Services Required To Complete All Work Specified Herein Indicated Or As Shown On The Drawings. • Work Includes But Is Not Limited To:  Wall Footing, 3500 Psi  Concrete Countertop Sink, 3500 Psi  Stiffener Columns And Lintel Beams At Door And Window Openings, Every 3m Width And 2.1m Height Of Chb 2500 Psi Iii.2. Standards • Except As Modified By Governing Codes And By Contract Documents, Comply With The Provisions And Recommendations Of The Following, Latest Edition:  Ansi American National Standards Institute  Astm American Society For Testing Of Materials  Aci American Concrete Institute  Nbcp National Building Code Of The Philippines And Its Revised Irr  Nscp National Structural Code Of The Philippines Iii.3. Concrete • Structural Concrete – Concrete Pouring Using Concrete Strength 3,500 Psi, Class Aa Ready Mix Or Job Mixed Concrete Together With The Concrete Cylinder Sample For Testing Materials. • Concrete Mix Shall Be Subject To Adjustment To Attain The Required Strength Or Desired Mix Consistency, Subject To Approval Of The Hospital Engineer. • Portland Cement, Type 1 • Manufactured Or River-run Run Gravel For Structural Concrete, ¾ “max Properly Graded” • Washed Sand For Structural Concrete • Water: Use Potable Water Free From Alkaline Or Deleterious Substance That May Affect The Strength Of Concrete. Use Of Rain Water Will Not Be Permitted. • All Materials Shall Be Free From Clay, Lumps Or Any Deleterious Object Or Matter That Will Impair The Strength Of Concrete. • Mixing Shall Be Thoroughly Done In A Mixer Of An Approved Size And Type To Insure A Uniform Distribution Of The Materials Throughout The Mass. • Site-mixed Concrete (job Mixed Concrete) - All Structural Concrete Shall Be Machine-mixed For At Least 1 ½ Minutes After All Materials Including Water Are In The Mixing Drum. No Hand Mixing Shall Be Allowed, Except In Case Of Emergency Of Breakdown During Pouring Operations. • Ready-mixed Concrete - Mixed And Delivered From A Plant Approved By The Project Manager, And Shall Be In Strict Compliance With The Requirements Set Forth In Astm C94. • Concrete Shall Be Placed Only After All Formworks, Materials To Be Embedded, And Preparation Of Surface Involved In The Placing Have Been Inspected And Approved By The Hospital Engineer. The Contractor Shall Provide Equipment And Shall Employ Methods That Will Minimize Separation Of Aggregates From The Concrete Mix. Concrete In Columns Shall Be Placed In One Continuous Operation. Concrete In Girders, Beams And Slabs In Superstructures Shall Be Poured In A Monolithic And Continuous Manner. No Construction Joint Shall Be Allowed On Any Part Of The Structure Without The Approval Of The Hospital Engineer. • Slump Of Concrete Shall Not Exceed 3 Inches • Placement Of Concrete Shall Be In Accordance To Standard Norms, When Using Portable Concrete Mixers. • Cure Concrete Sprinkling Water And Wetted Continuously For 7-day Period. Iii.4. Thermal Moisture Protection • Except As Modified By Governing Codes And By Contract Documents, Comply With The Provisions And Recommendations Of The Following, Latest Edition:  Ansi American National Standards Institute  Astm American Society For Testing Of Materials  Aci American Concrete Institute  Nbcp National Building Code Of The Philippines And Its Revised Irr  Nscp National Structural Code Of The Philippines Iii.5. Steel Reinforcements • Steel Reinforcements Shall Be Astm A615, Deformed Steel Bars, Grade 40. • Supply, Fabricate And Install Reinforcing Steel As Shown On Drawings. Placing Of Steel Reinforcements Shall Be In Accordance With Current Industry (local) Code (or Aci-347). • Secure The Reinforcements Using #16 G.i. Tie Wires. • Steel Reinforcement Shall Be Provided Together With All The Necessary Tie Wires, Spacers, Support And Other Necessary Devices. Reinforcing Steel Shall Be Accurately Cut And Bent In Accordance With The Approved Detailed Reinforcement Drawings. The Hospital Engineer May Require The Contractor To Prepare And Submit Bar Cutting Schedule Prior To Fabrication Of Reinforcing Steel Bars. • Steel Reinforcements Shall Be Free From Mill Scales, Rusts, Oils, Contamination That Will Impair The Bonding Property To Concrete. Iii.6. Structural Steel, Metal Works And Stainless Ladder (refer Chapter 5 Of The Nscp) • Provide All Labor, Materials, Equipment, Transportation, And Services Required To Complete All Work Specified Herein Indicated Or As Shown On The Drawings. • Work Includes But Is Not Limited To:  Prefabrication Of Stainless Steel 304 Ladder Handle, And Manhole Cover. • Materials Steel And Metals For The Works Shall Meet The Requirements Of Astm A36, Hot-rolled Shapes And Plates. • All Steels Shall Be Primed With Epoxy-based Paint With -2- Finish Coats, Color Sample Must Be Submitted To Architect’s/engineer’s For Approval. Substrate Preparation Shall Meet The Requirements Of The Applicable Clauses Of The Steel Structures Painting Council, For Industrial Type Of Construction. All Surfaces Shall Be Free From Mill Scale, Rusts, Oils Or Any Contaminants Detrimental To Adhesion Of Paint. • Welding Works Shall Be In Accordance With Structural Welding Code (american Welding Society-d1.1, Latest Edition). Welding Electrodes Shall Be E6013 And E6012, Minimum, Meeting The Requirements Of Aws A.5. All Welders Shall Meet The Qualifications Under The Aws Codes And Standards. • All Works Under This Item Shall Be Subject To Verification By The Engineer Prior To Commencement Of Fabrication. Contractor Is To Submit Shop Drawings For Architect’s/engineer’s Review Prior To Execution. Iii.7. Formworks • All Forms Shall Be Designed By The Contractor For A Safe Construction Activity And Installed To Dimensions Shown On The Drawings. • Use Phenolic Boards On Formworks With Shoring Supports. • Forms Shall Be Used Whenever Necessary To Confine The Concrete And Shape It To The Required Lines And Dimensions, Or To Protect The Concrete From Contamination. Forms Shall Have Sufficient Strength To Withstand The Pressure Resulting From Placement And Vibration Of The Concrete, And Shall Be Maintained Rigidly In Correct Position. Forms Shall Be Sufficiently Tight To Prevent Loss Of Mortar From The Concrete. • Stripping Of Forms Shall Only Commence After The Concrete Has Gained Sufficient Strength (min Of 7 Days) For Major Structural Elements. C. Architectural Works Furnish Materials And Labor And All Incidentals Necessary For The Completion Of All Architectural Works Shown On Drawings And As Herein Specified. I. Paint Finishes • Paint Materials And Samples Swatches Shall Be Approved By The Architect. • Examine Substrate And Conditions Under Which Painting Will Be Performed. Proceed With The Work Only When Conditions Are Satisfactory. • Do Not Paint Over Dirt, Rust, Scale, Grease, Moisture, Scuffed Surfaces, Or Conditions Otherwise Detrimental To Formation Of A Durable Paint Film. • Clean Surfaces To Be Painted Before Applying Paint Or Surface Treatments. Remove Oil And Grease Prior To Mechanical Cleaning. Program Cleaning And Painting So That Contaminants From Cleaning Process Will Not Fall Into Wet, Newly-painted Surfaces. • Perform Preparation And Cleaning Procedures In Accordance With Paint Manufacturer’s Instructions And As Herein Specified, For Each Particular Substrate Condition. • Ferrous Metals: Clean Non-galvanized Ferrous-metal Surfaces That Have Not Been Shop Coated; Remove Mortar, Plaster, Grease, Dirt, Rust, Loose Mill Scale And Other Foreign Substances By Solvent Or Mechanical Cleaning Methods That Comply With The Recommendations Of The Steel Structures Painting Council, Before Priming Coat Is Applied. I. Floor Finishes • Tile Works  General: All Surfaces To Receive Tiles, Shall Be Free From Loose Plaster, Where Required, Existing Setting Mortar Bed Shall Be Stripped, Removed To Allow Proper Setting Of Tiles To Desired Finished Elevation. No Separate Payment For Trimming Existing Mortar Bed And Shall Be Deemed Included Elsewhere.  Material Shall Be Subject To Review And Approval Of The Architect. Contractor To Submit Samples For Color And Texture Selection Prior To Delivery And Installation.  All Floor Cuttings On Both Ends Of The Walls Shall Be Of Equal Width.  Tile Grout Color To Match Color Of Tiles Or As Directed By The Architect.  Setting Bed Or Mortar Shall Be Dry Mixed, Sand-cement Mix With Water Added To Produce The Desired Consistency And Slurry Mix For Adhesion. Use Tile Adhesive For Areas That Are Less Than 1.5 Inches From Finish Floor Line.  All Exposed Corner Edges Shall Be Provided With Aluminum Stair Nosing.  No Human Traffic Or Construction Loads Shall Be Applied To All Newly Installed Tiles, And Allow Setting Mortar And Adhesive To Cure Prior. • Floor Tile Works  Common Areas – 60cmx60cm Glazed Ceramic Floor Tiles.  Service Areas – 60cmx60cm Unglazed, Non-skid Ceramic Floor Tiles.  Toilets And Janitor’s Closet – 30cmx30cm Non-skid Ceramic Floor Tiles.  Cuttings On Both Ends Of The Walls Shall Be Of Equal Width With The Floor Finish.  All Exposed Corner Edges Shall Be Provided With Pvc Tile Trims.  No Human Traffic Or Construction Loads Shall Be Applied To All Newly Installed Tiles, And Allow Setting Mortar And Adhesive To Cure Prior. Ii. Wall & Ceiling Finishes • Wall Tile Works  All Toilets – 30cmx60cm Glossy/polished Ceramic Tiles.  Cuttings On Both Ends Of The Walls Shall Be Of Equal Width With The Floor Finish.  All Exposed Corner Edges Shall Be Provided With Pvc Tile Trims. - No Human Traffic Or Construction Loads Shall Be Applied To All Newly Installed Tiles, And Allow Setting Mortar And Adhesive To Cure Prior. • Painting Works  Paint Materials And Samples Swatches Shall Be Approved By The Architect.  Examine Substrate And Conditions Under Which Painting Will Be Performed. Proceed With The Work Only When Conditions Are Satisfactory.  Do Not Paint Over Dirt, Rust, Scale, Grease, Moisture, Scuffed Surfaces, Or Conditions Otherwise Detrimental To Formation Of A Durable Paint Film.  Clean Surfaces To Be Painted Before Applying Paint Or Surface Treatments. Remove Oil And Grease Prior To Mechanical Cleaning. Program Cleaning And Painting So That Contaminants From Cleaning Process Will Not Fall Into Wet, Newly-painted Surfaces.  Perform Preparation And Cleaning Procedures In Accordance With Paint Manufacturer’s Instructions And As Herein Specified, For Each Particular Substrate Condition.  Ferrous Metals: Clean Non-galvanized Ferrous-metal Surfaces That Have Not Been Shop Coated; Remove Mortar, Plaster, Grease, Dirt, Rust, Loose Mill Scale And Other Foreign Substances By Solvent Or Mechanical Cleaning Methods That Comply With The Recommendations Of The Steel Structures Painting Council, Before Priming Coat Is Applied. • Painting Systems  Exterior Surfaces: - Concrete, Concrete Masonry, Rendered Smooth - Concrete Neutralizer – One (1) Coat, Dry For 6 Hours. - Putty Surface Imperfections, Hairline Cracks With Patching Compound Using Putty Knife - Prime – Two (2) Coats Flat Latex, Dry For Two (2) Hours. - Topcoat – Two (2) Coats Of Semi-gloss Latex, Two (2) Hours Interval Between Coats. - Thinning / Clean-up Solvent – Water - Application – By Brush, Roller, Or Airless Spray  Interior Surfaces: - Concrete, Concrete Masonry, Rendered Smooth - Concrete Neutralizer – One (1) Coat, Dry For 6 Hours. - Putty Surface Imperfections, Hairline Cracks With Patching Compound Using Putty Knife. - Prime – Two (2) Coats Flat Latex, Dry For Two (2) Hours. - Topcoat – Two (2) Coats Of Semi-gloss Latex, Two (2) Hours Interval Between Coats. - Thinning / Clean-up Solvent – Water - Application – By Brush, Roller, Or Airless Spray  Ceiling & Drywall Surfaces: - Repair Surface Imperfections With Putty Using Putty Knife, Dry For 2 Hours And Sand. - Apply Mesh Tape On Board Joints And Seal Gaps With Patching Compound. Dry For Two (2) Hours And Sand. - Primer – Flat Latex, Dry For Two (2) Hours. - Topcoat – Two (2) Coats Of White Flat Latex Paint, Two (2) Hours Interval Between Coats. - Thinning / Clean-up Solvent - Water - Application – By Brush, Roller, Or Airless Spray • Dry Ceiling, Cove Light & Drop Ceiling  Ceiling - Fiber Cement Board In 4.50mm X 1.2m X 2.4m  Fiber Cement Board Shall Be Stored In Elevated And Well Protected Area. Boards With Broken Edges, Lacerations Etc. Will Not Be Permitted To Be Installed.  Framing - On 0.40mm Thick, 19mm X 50mm Double Furring, And 0.80mm Thick, 12mmx38mm Carrying Channel With Vertical Hanger, Spaced At 0.40m X 0.40m On Centers. • Rendering To Chb Or Concrete Surfaces  All Surfaces To Be Rendered Or Cement Plastered Shall Be Clean From Any Loose Material Or Contamination To Provide Strong Bond Between Plaster And The Surface.  Mix Proportion Shall Not Be Less Than 1 Part Of Cement To 4 Parts Of Screened Sand. Necessary Adjustments Shall Be Made To Provide A Strong And Consistent Mix, Free From Cracking Due To Rapid Hydration Of Plaster Mix.  Tampering Of Previously Mix Concrete Will Not Be Permitted.  All Surfaces To Receive Paint Finish Shall Be Smooth Whilst Surfaces To Receive Tiles Shall Be Rough To Provide Better Adhesion Or Bond. • Doors And Windows  All Wooden Doors Shall Be Kiln Dried And Treated Flush Doors/panel Doors Ready For Installation With The Provisions For Accessories As Indicated On Drawings, Locksets, Door Keys, And Hinge Completely Operational.  All Door Jambs For Wooden Doors Shall Be Pre-fabricated 2”x6” And 2”x4” Wooden Jamb Finished With Automotive Lacquer Paint.  Glass Door (glass/glazing) – 12mm Thk. Tempered Clear Glass On 50mm X 100mm Powder-coated Frameless Sliding Door With 2" X 6" Powder Coated Aluminum Jamb With Complete Hardware Accessories.  Glass Door (glass/glazing) – 1/4” Thk. Clear Glass On 50mm X 100mm Powder-coated Aluminum Framed Sliding Door With 2" X 6" Powder Coated Aluminum Jamb With Complete Hardware Accessories.  Windows (glass/glazing) – 1/4” Mm Thk. Clear Glass Awning Type Analok Aluminum Frame W/ Complete Hardware Accessories And Window Frame Weatherstripping.  All Metal Doors And Jambs – Hollow Core Metal Flush Type Swinging Door With 2" X 6" Steel Jamb – All In Paint Finish By Spray, W/ Complete Hardware And Door Accessories Including Door & Jamb Seals As Indicated On Drawings, Completely Operational.  All Doors And Jambs – Provide All Door Keys With Key Chains And Key Tags With Color And Specifications Subject For Approval Of The Healthcare Facility. • Specialties  Concrete Countertop Sink - Finish – Glossy/polished, Ceramic Tiles, 60cm X 60cm, On All Areas As Indicated On Drawings - Inclusions – Countertop Backsplash And Aprons - Finish And Color – As Selected By Healthcare Facility - Cut Unit To Provide Pattern Indicated And In A Manner That Will Provide Clean, Sharp, Unchipped Edges.  Building/room Signages/wayfinding Systems  Ground Floor - Signages - Room Identification Sign - Chief Nurse Office, 6mm Thick Frosted Acrylic - Room Identification Sign - Pulmonary Unit, 6mm Thick Frosted Acrylic - Room Identification Sign - Physical Therapist Room, 6mm Thick Frosted Acrylic - Room Identification Sign - Janitors Closet, 6mm Thick Frosted Acrylic - Room Identification Sign - Electrical Room, 6mm Thick Frosted Acrylic - Room Identification Sign - Business Office, 6mm Thick Frosted Acrylic - Room Identification Sign - Stakeholders Office, 6mm Thick Frosted Acrylic - Room Identification Sign - Treatment Area, 6mm Thick Frosted Acrylic - Room Identification Sign - Doctors Office, 6mm Thick Frosted Acrylic - Room Identification Sign - Pantry, 6mm Thick Frosted Acrylic - Room Identification Sign - Water Treatment Room, 6mm Thick Frosted Acrylic - Room Identification Sign - Reprocessing Room, 6mm Thick Frosted Acrylic - Room Identification Sign - Waste Holding Area, 6mm Thick Frosted Acrylic - Room Identification Sign - Nurse Station, 6mm Thick Frosted Acrylic - Restroom Identification - Pwd Toilet, 6mm Thick Frosted Acrylic - Restroom Identification – All Gender Toilet, 6mm Thick Frosted Acrylic - Restroom Identification – Staff Toilet, 6mm Thick Frosted Acrylic - Emergency Exit Plan, 6mm Thick Frosted Acrylic G. Plumbing Works Provide All Labor, Materials And Equipment And Perform All The Work Necessary For The Complete Execution Of All The Work As Shown On Drawings And Specified In This Specification. Scope Of Works Shall Include But Does Not Be Limited To The Following Major Items Of Work: • Sanitary And Waterline Piping Works  Furnish And Install Complete Water Distribution System Including Incoming Supply Pipes And Connections, Pipes, Valves, Faucets, Accessories, Etc.  Storage, Delivery, Protection Before Installation And Connection Of Sanitary Line Accessories.  All Sanitary Pipes And Fittings To Be Used Shall Be Made Of Polyvinyl Chloride (pvc Pipes) Series 1000  All Waterline Pipes And Fittings To Be Used Shall Be Made Polypropylene Random Co-polymer (ppr Pipes)  Connections From Existing Water Supply And Existing Catch Basins.  Pressure Testing Of The Installed Water Distribution System.  Leakage Testing Of Soil, Waste, Vent, And Catch Basins And Septic Tank  Disinfections Of Water Distribution System.  Furnish And Install All Required Consumable Materials And Materials Tube Installed.  Investigation Of All Conflicts Of This Work And Coordination With Other Trades. • Plumbing Fixtures, Toilet & Sink Accessories * Submit Samples For Approval Prior To Installation" ** Faucets, Valves & Other Accessories Shall Be Japan, U.s., & E.u. Made  Two-piece Water Closet/s (push Button,4/6 Liters Water Saver) With Wall-mounted Semi- Recessed Ceramic Tissue Holder, Wall-mounted Semi-recessed Ceramic Soap Holder, With Complete Accessories  Lavatory With Pedestal W/ Faucet And W/ Complete Fittings & Accessories  600x400x200x0.8 Mm Stainless Steel Single Bowl Kitchen Sink W/ Complete Fittings & Accessories  Urinal W/ Complete Fittings & Accessories  Ss 304 Towel Bar  Stainless Faucet  Pwd Ss304 Grab Bar (l-type)  Pwd Ss304 Flip-up Bar  Pwd Ss304 Urinal Grab Bar, 2 Pcs Per Set  Stainless Steel 304/brass, Faucet, 1/2" X 6", For Sink  Floor Drain Stainless 6"x6"  Floor Drain Stainless 4"x4" H. Electrical Works Provide All Labor, Materials And Equipment And Perform All The Work Necessary For The Complete Execution Of All The Work As Shown On Drawings And Specified In This Specification. Scope Of Works Shall Include But Does Not Be Limited To The Following Major Items Of Work: • Panel Boards And Circuit Breakers At 3rd Floor  Mdp Assembled In Nema 1 Enclosure, Wall Mounted, Swing Dead Front, Powder Coated With Terminal Lugs In Crimping Type Ready, With Grounding Busbar Main: 300at/300af, 3p, 10kaic, 230 V, Bolt-on Type Mccb Branches: 1 - 60at/60af, 2p, 10kaic, 230 V, Mccb 2 - 125at/125af, 2p, 10kaic, 230 V, Mccb  Glp Assembled In Nema 1 Enclosure, Wall Mounted, Swing Dead Front, Powder Coated With Terminal Lugs In Crimping Type Ready, With Grounding Busbar Main: 60at/60af, 3p, 10kaic, 230 V, Bolt-on Type Mccb Branches: 12 - 20at/60af, 2p, 10kaic, 230 V, Mcb 2- Space  Gpp Assembled In Nema 1 Enclosure, Wall Mounted, Swing Dead Front, Powder Coated With Terminal Lugs In Crimping Type Ready, With Grounding Busbar Main: 125at/125af, 3p, 10kaic, 230 V, Bolt-on Type Mccb Branches: 18 - 30at/60af, 2p, 10kaic, 230 V, Mcb 2- Space  Gpacu Assembled In Nema 1 Enclosure, Wall Mounted, Swing Dead Front, Powder Coated With Terminal Lugs In Crimping Type Ready, With Grounding Busbar Main: 125at/125af, 3p, 10kaic, 230 V, Bolt-on Type Mccb Branches: 14 - 30at/60af, 2p, 10kaic, 230 V, Mcb 2- Space • Roughing-ins  20mm Dia. Upvc Pipe, Male Adapter With Locknut  25mm Dia. Upvc Pipe, Male Adapter With Locknut  20mm Corrugated Electrical Flexible Hose  20mm Electrical Flexible Hose Connector  32mm Dia. Upvc Pipe, Male Adapter With Locknut  50mm Dia. Upvc Pipe, Male Adapter With Locknut  65mm Dia. Upvc Pipe, Male Adapter With Locknut  Junction Box With Cover  Utility Box  Square Box  Consumables • Wires And Cables  Thhn/thwn Wire - 2.0mm², 3.5mm², 5.5mm², 8.0mm², 14.0mm², 22.0mm², 50.0mm², 60.0mm², 80.0mm² • Wiring Devices  Single Pole Switch With Led Indicator, Flush Type Modern Series  Duplex Switch With Led Indicator Flush Type Modern Series  Triplex Switch With Led Indicator Flush Type Modern Series  Single Universal Convenience Outlet, 3 Prong Modern Series, 16a, 230v  Duplex Universal Convenience Outlet, 3 Prong Modern Series, 16a, 230v  Duplex Universal Outlet, Floor Mounted Type, 16a, 230v  Gfci Outlet  Acu Outlet, Universal, 30a, 230v W/ Grounding-type • Lighting Fixtures  4"ø Downlight, With 11w Led Recessed Mounted  2x18w Troffer Led Panel Type Lighting Fixture  Emergency Light  Exit Light  30 Watts Led Flood Light I. Auxiliary Works To Include Fixing And Installation; Complete Accessories And Necessary Consumables; All In Accordance With Auxiliary Plan And Specification And As Indicated On Detailed Cost Estimates: • Fire Alarm And Detection System  Roughing-ins / Wires: - 15mmø Emt Pipe, Coupling, Connector - Pull Box - Metal Flexible Conduit 1/2" - Straight Connector 1/2" - Junction Box W/ Cover - Utility Box - Conduit Supports / Hangers - 1.25mm2 Twisted Pair - Consumables - Equipment: - Smoke Detector - 24v Sounder & Strobe Light (combined) - Manual Push Station 24v - Fire Alarm Control Panel 3 Zones, W/ Back-up Battery, 24v • Paging System  Roughing-ins / Wires: - 15mmø Upvc Pipe, Male Adapter With Locknut - Metal Flexible Conduit 1/2" - Straight Connector 1/2" - Junction Box With Cover - 1.25mm2 Twisted Pair - Consumables - Equipment: - Ceiling Speaker • Tel/lan System  Roughing-ins / Wires: - 15mmø Upvc Pipe - 15mm Dia. Upvc Male Adapter With Locknut - Junction Box With Cover - Utility Box With Cover - Utp Cat 6 4pairs - 1 Gang Outlet - Consumables  Equipment: Telephone And Data Outlet • Cctv System  Roughing-ins / Wires: - 15mmø Upvc Pipe - 15mm Dia. Upvc Male Adapter With Locknut - Junction Box With Cover - Utility Box With Cover - Utp Cat 6 4pairs - 1 Gang Outlet - Consumables  Equipment: - Ip Camera Dome Type J. Fire Protection Works To Include Fixing And Installation; Complete Accessories And Necessary Consumables; All In Accordance With Fire Protection Plan And Specification. • Black Iron Pipes, Fittings, Valves And Accessories: - Bi Pipes Schedule 40 @ 6m, Seamless (also Including Drain Pipe Riser And Auto Sprinkler Riser) And All Fittings, Valves And Accessories As Indicated On Detailed Cost Estimates • Sprinkler Heads And Accessories - Pendent Type: 135 Degrees To 165 Degrees • Others – Hangers And Supports, Miscellaneous And Consumables (including Painting And Tagging) • Testing And Commissioning – Configuration, Testing And Commissioning, Documentation, Training And Orientation K. Mechanical Works To Include Fixing And Installation; Complete Accessories And Necessary Consumables; All In Accordance With Mechanical Plan And Specification And As Indicated On Detailed Cost Estimates: • Air-conditioning Works - 4.0 Hp Split Type Aircon, Inverter Type, - 2.5 Hp Split Type Aircon, Inverter Type - 1.0 Hp Split Type Aircon, Inverter Type - Consumables - L. Request For Final Inspection • Contractor Shall Submit Its Written Request For A Final Inspection Of The Project To The Medical Center Chief Office At Least Seven (7) Days Prior To Project Inspection & Turn-over. M. Tools And Equipment • Various Basic And Advanced Masonry/electrical/carpentry Tools • Measuring And Layout Tools • Safety Equipment • Utility Vehicle N. Technical Personnel Required • Project Engineer • Foreman • Leadman • Skilled Personnel (mason, Carpenter, Steelman, Electrician, Plumber) • Laborer/helper General Guidelines • All Construction Works Shall Be Undertaken By Contractor In Accordance With Existing Laws And All Other Applicable Rules And Regulations. • The Contractor Shall Be Responsible In Setting Out Reference Lines, Elevations (lines And Grades) Prior And During The Execution Of The Works. All References Shall Be Maintained And Protected By The Contractor At His Own Expense. Disturbed References Shall Be Restored To Its Original Position Without Extra Cost To Devmh. • The Contractor Shall Carry Out The Works Properly And In Accordance With This Contract. The Contractor Shall Provide All Supervision, Labor, Materials, Plant And Equipment, Which May Be Required. • The Contractor Shall Commence Execution Of The Works On The Start Date And Shall Carry Out The Works In Accordance With The Approved Pert/cpm Network Diagram Submitted By The Contractor, As Updated With The Approval Of The Procuring Entity’s Representative, And Shall Complete The Works By The Intended Completion Date. • The Contractor Shall Be Responsible For The Safety Of All Activities On The Site. • During On-going Construction And Before The Turn-over Of The Project, Engineering & Facilities Management Staff, End-users, Twg And Bac Shall Inspect The Works Undertaken By Contractor. Hospital Engineers And End-users Discover Any Deviations By Contractor From The Approved Construction Plans, Contractor Shall Be Required To Rectify All Such Deviations, Within Such Period Required By Client. • Contractor Shall Have Full Responsibility For Any And All Damages To Existing Hospital Facilities, Utilities, And/or Any Portion Of The Hospital’s Common Area, Due To The Works Undertaken By Contractor, Whether Accidental Or Intentional. • No Variation Order Shall Be Undertaken Unless Verified By Hospital Engineer And Approved By Executive Committee. • Contractor Shall Not Cover Or Block Stub-outs (cleanouts, Water Source, Exhaust, Sewer, Drainage, Etc.) When Not Utilized. Said Stub-outs Shall At All Times Be Free Of Obstructions And Easily Accessible. • Contractor Shall Secure A Utility Tapping Permit Prior To Tapping From Utility Provision. • Electricity And Water Consumed During Construction Shall Be Charged To Contractor. • End-users Reserves The Right To Inspect The Works At Any Time. • Contractor Shall Insure And Hold Client, Its Affiliates, Officers, Directors, Stockholders, Employees, Agents, And/or Representatives, Free And Harmless From And Against Any Injury, Losses, Claims, Damages, Liabilities, Expenses, And/or Costs Of Litigation, Resulting From Or Arising Out Of The Works Undertaken By Contractor. • In Event Of Force Majeure, The Contractor Shall Rectify, Replace Or Build The Unfinished Projects When It Is Not Yet Completed And Accepted W/o Additional Cost For The Procuring Entity. • Contractor Shall Comply With The Construction House Rules Of This Hospital. Time Of Completion • The Completion Of The Project Shall Be One-hundred Twenty (120) Calendar Days From The Date Of Effectivity.

Details: Description Project Title : Construction Of Isolation Building With Negative Pressure – Phase Iii Location : Devmh Compound, Bood, Ubay, Bohol Estimated Project Cost : Php 10,000,000.00 Terms Of Reference Summary Of Works A. General Requirements I. Mobilization/demobilization • The Work Consists Of The Mobilization And Demobilization Of The Contractor’s Forces And Equipment Necessary For Performing The Work Required Under The Contract. Ii. Permits And Licenses • Process And Submit Electrical Design Review Including Sign And Seal Of Electrical Plans, Electrical Review, Analysis, Computations And Signature Of Pee On Electrical Plans And Including All Forms And Plans For The Application Of Permit To Construct (ptc) For Doh Licensing. Design And Analysis Should Be Submitted Prior To Commencement Of Civil Works. Iii. Temporary Facilities • Temporary Facilities Shall Be Provided During The Construction Period And Will Be Constructed Within The Hospital Compound, Which Shall Serve As The Field Office, Storage Of Materials And Bunkhouse For The Workers. The Contractor Shall Provide And Maintain Temporary Power & Lighting, Temporary Water Service & Security Within The Construction Site. Iv. Health, Safety & Environment Control (complete Ppe, Safety Equipment & Devices & Safety Accessories And Signages) • Safety/warning Signage Must Be Placed By The Contractor On The Construction Area With Clear Demarcation Of Construction Zones To Prevent Unauthorized Access. • Detours And Closures: Provide Directions For Alternate Routes And Notice Of Any Closed Areas. • Hazard Notifications: Provide Signs Indicating Potential Dangers In Construction Areas (e.g., "hard Hat Area," "no Entry"). • Emergency Information: Clear Guidance On Emergency Exits And Procedures During Construction. • Fall Protection: Always Use Safety Harnesses And Guardrails. • Weather Conditions: Avoid Dismantling In High Winds, Rain, Or Extreme Temperatures. • Team Communication: Maintain Clear Communication Among Team Members And Healthcare Facility Engineering Team To Coordinate Movements And Tasks. V. As-built (record) Drawings & Related Documents • Submit One (1) Completed Set Of Signed And Sealed As-built Plans (whiteprint Copy) • Submit One (1) Set Of Electronic Files Of Signed And Sealed As-built Plans (cadd Editable File) • The Drawings Shall Be Supplemented With Descriptive Specification As Appropriate To Clearly Record The Exact Form And Content Of Work Described In This Specification And On The Drawings. • Maintain A Complete And Accurate Record Of All Changes Or Deviations To The Contract Documents And Shop Drawings In The Trade Contractor’s Field Office. Such Record Copy Shall Indicate The Work As Actually Constructed And Be Available For Hospital Appointed Engineer To Review. • Incorporate All Minor Revisions And Clarifications Noted Thru The Field Modification Process Which May Not Necessarily Be Shown On The Architectural Drawings Or Issued As Addenda, Bulletins, Or Change Orders. • Field Changes Shall Be Neatly And Correctly Shown On One Set Of Record Prints On A Daily Basis By The Foreman, Or Superintendent Of Ea • Ch Trade; And This Set Will Act As A Record Set At Completion Of The Work And Is Intended To Be Of Assistance To The Trade Contractor In Preparing Record Documents. Vi. Material Sustainability • The Contractor Shall Use At Least Ten Percent (10%) Locally Manufactured Materials For The Project. Submit Purchase Order And Other Supporting Documents As Evidence. • The Contractor Shall Avoid Using Building Materials/products That Contain Toxic Chemicals Or Use Materials That Are Low In Volatile Organic Compound. Please Refer To The Following Materials Specification As Stated On This Terms Of Reference. • The Contractor Shall Only Used Light Bulbs And Electrical Devices With More Efficient Models And Type As Specified On Approved And Signed Bill Of Quantities (e.g. Led Bulbs). Submit Purchase Order And Other Supporting Documents As Evidence. • The Contractor Shall Conform To The Following Painting And Other Wet Applied Materials (such As Coatings, Sealants) Requirements: 1. Only Qualified Products With Mpi "environmentally Friendly" E1 E2 E3 Rating Will Be Used. Paints, Coatings, Thinners, Solvents, Cleaners And Other Fluids Used In Repainting, Shall:  Not Contain Methylene Chloride, Chlorinated Hydrocarbons, Toxic Metal Pigments.  Be Manufactured Without Compounds Which Contribute To Ozone Depletion In The Upper Atmosphere.  Be Manufactured Without Compounds Which Contribute To Smog In The Lower Atmosphere. Be Manufactured In A Manner Where Matter Generating A 'biochemical Oxygen Demand' (bod) In Undiluted Production Plant Effluent Discharged To A Natural Watercourse Or A Sewage Treatment Facility Lacking Secondary Treatment Does Not Exceed 15 Mg/l.  Be Manufactured In A Manner Where The Total Suspended Solids (tss) Content In Undiluted Production Plant Effluent Discharged To A Natural Watercourse Or A Sewage Treatment Facility Lacking Secondary Treatment Does Not Exceed 15 Mg/l. 2. Paints And Coatings Must Be Manufactured And Transported In A Manner That Steps Of Processes, Including Disposal Of Waste Products Arising There From, Will Meet Requirements Of Applicable Governmental Acts, By-laws And Regulations In The Philippines. 3. Paints And Coatings Must Not Be Formulated Or Manufactured With Formaldehyde, Halogenated Solvents, Mercury, Lead, Cadmium, Hexavalent Chromium Or Their Compounds. Eco Labeled. 4. Anti-corrosive Coatings: Provide A Certification By The Manufacturer That Products Supplied Comply With The Volatile Organic Compound (voc) And Chemical Component Restrictions Of Green Seal Environmental Standard Gc-03, If The Product Is An Anti-corrosive Coating Applied Indoors And On-site. 5. Other Interior Coatings: If The Product Is Applied Indoors And On-site, And Not Covered By Both The Green Seal Environmental Standard Gs-11 And Standard Gc-03, Provide A Certification By The Manufacturer That Products Supplied Comply With The Chemical Component Restrictions Of The Green Seal Environmental Standard Gs-11, Paints, And Comply With The Volatile Organic Compound (voc) Restrictions Of The State Of California Air Resources Board (carb) Suggested Control Measure For Architectural Coatings, And The South Coast Air Quality Management District Rule 1113: Architectural Coatings B. Civil Works I. Site Works • The Contractor Shall Be Responsible In Setting Out Reference Lines, Elevations (lines And Grades) Prior And During The Execution Of The Works. All References Shall Be Maintained And Protected By The Contractor At His Own Expense. Disturbed References Shall Be Restored To Its Original Position Without Extra Cost To The Healthcare Facility. • Work Includes But Is Not Limited To:  Dismantling Of Chb Walls For Windows 01, 02 & 03  Dismantling Of Chb Walls For Doors 01 & 02  Dismantling Of Ceiling Board For Installation Of Additional Mepfs Works  Scaffolding For Painting Works (installation & Dismantling)  Roof Deck Coring Works For Mepfs Ii. Structural & Concrete Works (refer Applicable Sections On Chapter 4 Of The Nscp, For Quality Of Materials, Workmanship, Execution, Acceptance, Etc.) Iii.1. General • Provide All Labor, Materials, Equipment, Transportation, And Services Required To Complete All Work Specified Herein Indicated Or As Shown On The Drawings. • Work Includes But Is Not Limited To:  Slab On-grade, 3500 Psi (ground Floor Ramp Area Slab, Grid A-f, 1-2)  Concrete Countertop Sink, 3500 Psi  Stiffener Columns And Lintel Beams At Door And Window Openings, Every 3m Width And 2.1m Height Of Chb 2500 Psi Iii.2. Standards • Except As Modified By Governing Codes And By Contract Documents, Comply With The Provisions And Recommendations Of The Following, Latest Edition:  Ansi American National Standards Institute  Astm American Society For Testing Of Materials  Aci American Concrete Institute  Nbcp National Building Code Of The Philippines And Its Revised Irr  Nscp National Structural Code Of The Philippines Iii.3. Concrete • Structural Concrete – Monolithic Concrete Pouring Using Concrete Strength 3,500 Psi, Class Aa Ready Mix Or Job Mixed Concrete Together With The Concrete Cylinder Sample For Testing Materials. • Concrete Mix Shall Be Subject To Adjustment To Attain The Required Strength Or Desired Mix Consistency, Subject To Approval Of The Hospital Engineer. • Portland Cement, Type 1 • Manufactured Or River-run Run Gravel For Structural Concrete, ¾ “max Properly Graded” • Washed Sand For Structural Concrete • Water: Use Potable Water Free From Alkaline Or Deleterious Substance That May Affect The Strength Of Concrete. Use Of Rain Water Will Not Be Permitted. • All Materials Shall Be Free From Clay, Lumps Or Any Deleterious Object Or Matter That Will Impair The Strength Of Concrete. • Mixing Shall Be Thoroughly Done In A Mixer Of An Approved Size And Type To Insure A Uniform Distribution Of The Materials Throughout The Mass. • Site-mixed Concrete (job Mixed Concrete) - All Structural Concrete Shall Be Machine-mixed For At Least 1 ½ Minutes After All Materials Including Water Are In The Mixing Drum. No Hand Mixing Shall Be Allowed, Except In Case Of Emergency Of Breakdown During Pouring Operations. • Ready-mixed Concrete - Mixed And Delivered From A Plant Approved By The Project Manager, And Shall Be In Strict Compliance With The Requirements Set Forth In Astm C94. • Concrete Shall Be Placed Only After All Formworks, Materials To Be Embedded, And Preparation Of Surface Involved In The Placing Have Been Inspected And Approved By The Hospital Engineer. The Contractor Shall Provide Equipment And Shall Employ Methods That Will Minimize Separation Of Aggregates From The Concrete Mix. Concrete In Columns Shall Be Placed In One Continuous Operation. Concrete In Girders, Beams And Slabs In Superstructures Shall Be Poured In A Monolithic And Continuous Manner. No Construction Joint Shall Be Allowed On Any Part Of The Structure Without The Approval Of The Hospital Engineer. • Slump Of Concrete Shall Not Exceed 3 Inches • Placement Of Concrete Shall Be In Accordance To Standard Norms, When Using Portable Concrete Mixers. • Cure Concrete Sprinkling Water And Wetted Continuously For 7-day Period. Iii.4. Thermal Moisture Protection • Except As Modified By Governing Codes And By Contract Documents, Comply With The Provisions And Recommendations Of The Following, Latest Edition:  Ansi American National Standards Institute  Astm American Society For Testing Of Materials  Aci American Concrete Institute  Nbcp National Building Code Of The Philippines And Its Revised Irr  Nscp National Structural Code Of The Philippines Iii.5. Steel Reinforcements • Steel Reinforcements Shall Be Astm A615, Deformed Steel Bars, Grade 40. • Supply, Fabricate And Install Reinforcing Steel As Shown On Drawings. Placing Of Steel Reinforcements Shall Be In Accordance With Current Industry (local) Code (or Aci-347). • Secure The Reinforcements Using #16 G.i. Tie Wires. • Steel Reinforcement Shall Be Provided Together With All The Necessary Tie Wires, Spacers, Support And Other Necessary Devices. Reinforcing Steel Shall Be Accurately Cut And Bent In Accordance With The Approved Detailed Reinforcement Drawings. The Hospital Engineer May Require The Contractor To Prepare And Submit Bar Cutting Schedule Prior To Fabrication Of Reinforcing Steel Bars. • Steel Reinforcements Shall Be Free From Mill Scales, Rusts, Oils, Contamination That Will Impair The Bonding Property To Concrete. Iii.6. Structural Steel, Metal Works (refer Chapter 5 Of The Nscp) • Provide All Labor, Materials, Equipment, Transportation, And Services Required To Complete All Work Specified Herein Indicated Or As Shown On The Drawings. • Work Includes But Is Not Limited To:  Prefabrication Of Façade Louver Installation • Materials Steel And Metals For The Works Shall Meet The Requirements Of Astm A36, Hot-rolled Shapes And Plates. • All Steels Shall Be Primed With Epoxy-based Paint With -2- Finish Coats, Color Sample Must Be Submitted To Architect’s/engineer’s For Approval. Substrate Preparation Shall Meet The Requirements Of The Applicable Clauses Of The Steel Structures Painting Council, For Industrial Type Of Construction. All Surfaces Shall Be Free From Mill Scale, Rusts, Oils Or Any Contaminants Detrimental To Adhesion Of Paint. • Welding Works Shall Be In Accordance With Structural Welding Code (american Welding Society-d1.1, Latest Edition). Welding Electrodes Shall Be E6013 And E6012, Minimum, Meeting The Requirements Of Aws A.5. All Welders Shall Meet The Qualifications Under The Aws Codes And Standards. • All Works Under This Item Shall Be Subject To Verification By The Engineer Prior To Commencement Of Fabrication. Contractor Is To Submit Shop Drawings For Architect’s/engineer’s Review Prior To Execution. Iii.7. Formworks • All Forms Shall Be Designed By The Contractor For A Safe Construction Activity And Installed To Dimensions Shown On The Drawings. • Use Phenolic Boards On Formworks With Shoring Supports. • Forms Shall Be Used Whenever Necessary To Confine The Concrete And Shape It To The Required Lines And Dimensions, Or To Protect The Concrete From Contamination. Forms Shall Have Sufficient Strength To Withstand The Pressure Resulting From Placement And Vibration Of The Concrete, And Shall Be Maintained Rigidly In Correct Position. Forms Shall Be Sufficiently Tight To Prevent Loss Of Mortar From The Concrete. • Stripping Of Forms Shall Only Commence After The Concrete Has Gained Sufficient Strength (min Of 7 Days) For Major Structural Elements. C. Thermal Moisture Protection Furnish Materials And Labor And All Incidentals Necessary For The Completion Of All Thermal Moisture Protection Works Shown On Drawings And As Herein Specified. I. Moisture Protection – Cold Fluid Applied Waterproofing • Work Includes But Is Not Limited To:  Waterproofing Of All Toilet Floors  Waterproofing Of Roof Deck • Project Conditions:  Proceed With Waterproofing Operations Only After Substrate Construction And Penetrating Work Have Been Completed.  Proceed With Waterproofing Operations Only When Existing And Forecast Weather Conditions Will Permit Work To Be Performed In Accordance With Manufacturer’s Recommendations. Ii. Leak Plug: Rapid-setting Mortar For Plugging Leaks On Concrete & Sealant On Pipe Penetrations & Embedded Steel Ladder • Provide Leak Plug That Is An Ultra-rapid Set Plugging Mortar For Sealing Running Water Leaks Where Conventional Mortars Would Otherwise Be Washed Away. It Should Be Ideal For Sealing Leaks Before Applying Waterproof Renders In Cistern Tanks. Upon Setting, The Product Should Develop Excellent Structural Strength And Water Tightness. It Is Supplied As A Dry Powder That Needs Only The Addition Of Water. • Specifications:  Rapid-setting, Stopping Leaks Instantly  Easy To Use – Just Add Water  Durable – Provides Sufficient Strength  Chloride-free – Doesn’t Cause Corrosion, And Non-toxic • Uses For:  Sealing And Creating Coving On Corner Joints  Stopping Leaks  Filling Holes Before Waterproofing, Including The Cold-joints • Surface Preparation: Surfaces Should Be Brushed Clean To Remove Loose Material, Dust, And Laitance. Holes To Be Patched Should Be Cut Back To A Depth Of 20mm, And Feather Edges Must Not Be Allowed. Allowance Should Be Made For Wastage When Estimating. • General Application: Strictly Comply With Manufacturer's Written Installation Instructions, Including Preparation Of Substrate Surfaces, Detail Coatings Of Joints And Planar Changes In Substrate, And Priming Of Substrates. Apply The Mixed Leak Plug In Place, Ensuring Maximum Contact With The Substrate Before The Material Sets. If Being Used To Plug A Running Water Leak, The Mixed Leak Plug Should Be Held In Place Until It Reaches The Initial Set. Iii. Sealant On Pipe Penetrations • Provide A Heavy-duty Sealant That Is A Formulated Polymer Which Serves As A Multi-purpose Adhesive And Sealant. It Is A Rubber-like, Flexible, Single Component, Moisture Cure Adhesive, And Sealant That Is Engineered For The Bonding And Sealing Needs Of The Construction And Automotive Industry. • Specifications:  Heavy Duty Adhesive And Sealant  Excellent Adhesion To A Wide Variety Of Substrates  Interior / Exterior Application  Highly Flexible And Elastic  Durable With High Tensile And Shear Strength  Uv And Weather Resistance  Paintable  Easy Clean Up  Non-staining  No Solvent, Isocyanate, Voc Iv. Two-component, Flexible Cementitious Waterproofing Membrane • Provide A Two-component, Flexible Cementitious Waterproofing Membrane, Consisting Of A Selected Cement Blend With Well-graded Fillers And Synthetic Resin. • Specifications:  Flexible, Durable And Weather-resistant  Excellent Adhesion To Most Substrates  Excellent Waterproofing Qualities – Able To Withstand High Hydrostatic Pressure  Breathable Membrane – Permeable To Water Vapor And Yet Impermeable To Water  Bridge Hairline Cracks  Non-toxic – Suitable For Use In Waterproofing Of Potable Water Tanks  Can Be Applied Onto Damp Surfaces • General Applications: For Horizontal And Vertical Surfaces, A Roller And/or Paint Brush May Be Used To Apply The Slurry. Care Must Be Taken To Ensure That Air Is Not Entrapped In The Membrane. Apply The First Coat And Work Generously To Fill All The Pores And Honeycombs. Allow The Membrane To Dry For Approximately 2 To 3 Hours Before Application Of The Second Coat. The Second Coat Must Be Applied In A Crosswise Manner To Ensure An Even Coverage. Allow A Minimum Curing Time Interval Of 15 To 72 Hours Before Laying The Screed Or Performing A Ponding Test. Should The Ponding Test Exceed 4 Hours, A Minimum Curing Time Interval Of 72 Hours Is Recommended. Concrete Topping Is Recommended For Exposed Areas Subject To Regular Traffic. Apply A Thin Film Of Bonding Agent Before Applying The Concrete Topping. D. Architectural Works Furnish Materials And Labor And All Incidentals Necessary For The Completion Of All Architectural Works Shown On Drawings And As Herein Specified. I. Paint Finishes • Paint Materials And Samples Swatches Shall Be Approved By The Architect. • Examine Substrate And Conditions Under Which Painting Will Be Performed. Proceed With The Work Only When Conditions Are Satisfactory. • Do Not Paint Over Dirt, Rust, Scale, Grease, Moisture, Scuffed Surfaces, Or Conditions Otherwise Detrimental To Formation Of A Durable Paint Film. • Clean Surfaces To Be Painted Before Applying Paint Or Surface Treatments. Remove Oil And Grease Prior To Mechanical Cleaning. Program Cleaning And Painting So That Contaminants From Cleaning Process Will Not Fall Into Wet, Newly-painted Surfaces. • Perform Preparation And Cleaning Procedures In Accordance With Paint Manufacturer’s Instructions And As Herein Specified, For Each Particular Substrate Condition. • Ferrous Metals: Clean Non-galvanized Ferrous-metal Surfaces That Have Not Been Shop Coated; Remove Mortar, Plaster, Grease, Dirt, Rust, Loose Mill Scale And Other Foreign Substances By Solvent Or Mechanical Cleaning Methods That Comply With The Recommendations Of The Steel Structures Painting Council, Before Priming Coat Is Applied. I. Floor Finishes • Tile Works  General: All Surfaces To Receive Tiles, Shall Be Free From Loose Plaster, Where Required, Existing Setting Mortar Bed Shall Be Stripped, Removed To Allow Proper Setting Of Tiles To Desired Finished Elevation. No Separate Payment For Trimming Existing Mortar Bed And Shall Be Deemed Included Elsewhere.  Material Shall Be Subject To Review And Approval Of The Architect. Contractor To Submit Samples For Color And Texture Selection Prior To Delivery And Installation.  All Floor Cuttings On Both Ends Of The Walls Shall Be Of Equal Width.  Tile Grout Color To Match Color Of Tiles Or As Directed By The Architect.  Setting Bed Or Mortar Shall Be Dry Mixed, Sand-cement Mix With Water Added To Produce The Desired Consistency And Slurry Mix For Adhesion. Use Tile Adhesive For Areas That Are Less Than 1.5 Inches From Finish Floor Line.  All Exposed Corner Edges Shall Be Provided With Aluminum Stair Nosing.  No Human Traffic Or Construction Loads Shall Be Applied To All Newly Installed Tiles, And Allow Setting Mortar And Adhesive To Cure Prior. • Anti-bacterial Vinyl Sheet Works Work Includes But Is Not Limited To:  3mm Anti-bacterial Vinyl Sheets With Cove And Capping – All Areas As Indicated On Drawings.  Installation Materials: - Trowelable Leveling And Patching Compounds: Latex-modified, Portland Cement Based Or Blended Hydraulic Cement-based Formulation Provided Or Approved By Resilient Product Manufacturer For Applications Indicated. - Adhesives: Water-resistant Type Recommended By Manufacturer To Suit Floor Tile And Substrate Conditions  Installation Should Be Carried In Accordance With Local Standards. Subfloor To Be Smooth, Hard, Clean And Dry Prior To Laying.  Project Condition: - Maintain Temperatures Within Range Recommended By Manufacturer, But Not Less Than Deg C Or More Than 35 Deg C, In Spaces To Receive Floor Tile During The Following Time Periods: 1. 48 Hours Before Installation. 2. During Installation. 3. 48 Hours After Installation. - After Post-installation Period, Maintain Temperatures Within Range Recommended By Manufacturer, But Not Less Than 13 Deg C Or More Than 35 Deg C. - Close Spaces To Traffic During Floor Covering Installation. - Close Spaces To Traffic For 48 Hours After Floor Covering Installation. - Install Resilient Products After Other Finishing Operations, Including Painting, Have Been Completed.  Color And Patterns: - Colors And Patterns: As Selected By The Healthcare Facility From Manufacturer's Full Range.  Positioning: - As Far As Possible, And Depending On The Width Of The Rolls, Seams Between Strips Should Be Kept Away From Areas Of Heavy Load. - Within Rooms, Strips Should Be Laid Towards The Main Window Or In A Lengthwise Direction. - Within Corridors, Strips Should Be Laid In The Direction Of Pedestrian Traffic Unless Otherwise Stated In The Contract Specifications. Apply The Flooring Along The Chalk Line. - Mark A Longitudinal Axis For Reference To Place Strips. - Unroll Fully Material. - Check That The Edge Of Strips Is Straight. Align The Edge Of The First Strip To Longitudinal Axis To Have A Straight Reference. - Leave A Gap Of 1 Cm Between Every Strip To Let Possible Full Material Acclimation In Its Length As In Its Width. If Area Is Too Small, It Is Possible To Overlap Fully Two Strips. Welding Joints: Leave A Space Of Max 1 Mm Between The Strips Cold Seaming: Overlap The Strips In Order To Cut Edges Flush - Let Material Relax During 24h. Material Will Be In The Best Conditions To Be Glued And Material Tensile Or Bubbles Will Be Mostly Released.  Gluing And Fitting: - This Is Done 24 Hours After Having Unrolled And Laid Out The Lengths. - The Application Is Done By Priming And Using Acrylic Emulsifying Adhesives With A Finely Toothed Spatula Or Trowel A2 Norm Tkb Or 1/16” X 1/16” X 1/16” Square Notch (1.6 Mm X 1.6 Mm X 1.6 Mm). Coverage Rate Is 300 Gr/sqm. To Achieve This Coverage, It Is Necessary To Change The Spatula Regularly. Important: - Forbid Any Trafficking For 48 Hours After Laying As Well As Any Furniture Movement. - Follow Carefully The Recommendations Of The Adhesive Manufacturer. - Closely Follow The Adhesive Manufacturer’s Instructions With Particular Regard To Its Waiting Time (the Interval Between Application Of Adhesive And Laying Of Flooring). - Room Temperature And Humidity, Sub-floor Absorption And Adhesive Coverage Are Important In Order To Achieve Perfect Adhesion. Fold Back Half Of The Strips When Applying Glue To The Floor  Rolling Out: - Rolling Out Should Be Done In Two Stages: 1. Manually, Using A Cork Smoothing Press 2. By Rolling Over The Entire Surface With A 50kg Roller When Installation Is Complete. Stage 1: Pressing Down Manually Stage 2: Using A 50kg Roller - Trimming The Edge: 1. Use Of Coving As A Skirting System.  Welding: - Heat Welding Requires A Small Gap 1 Mm Max To Be Left Between The Sheets During The Gluing Process. Cold Welding Requires Perfectly Straight Edges. Employ An Overlap Cutting Method During The Gluing Process.  Putting Into Service – Allowing Traffic: After Installation: - For Normal Pedestrian Traffic, Allow 48 Hours - Before Moving Or Installing Furniture, Allow 72 Hours • Resinous Floor Coating System Works  Work Includes But Is Not Limited To: - Non-skid Polyurethane Floor Coating (ff-4) – Of Ramp, Mid-landing, Landing And Janitor’s Closet At 3rd Floor , And As Indicated On Drawings.  Product: - Performance Requirements: Non-skid Polyurethane Floor Coating (ff-4) – Provide A Modified Polyurethane Floor Coating Formulated For High Performance And Resistance To Abrasion. Special Kinds Of Aggregates Were Added To Offer Anti-slip For Protection Against Harmful Or Dangerous Slips On Dry And Wet Floorings. Low-emitting Materials: Flooring System Shall Comply With The Testing And Product Requirements Of The California Department Of Public Health's (formerly, The California Department Of Health Services') "standard Method For The Testing And Evaluation Of Volatile Organic Chemical Emissions From Indoor Sources Using Environmental Chambers." - Specifications: - Better Anti-slip Grip - Durable And Excellent Color Retention - Low Odor And Non-toxic - Excellent Adhesion On Surfaces - Non-flammable - Recommended Paint System: - Primer: 1 Coat Of A Two-component, 100% Solids Epoxy Specially Formulated As A High-strength Primer For Use In Priming All Concrete Surface And Steel Prior To The Application Of Any Resin-based Floor Coatings And Toppings. - High-protective Coating - Pigmented Binder For Seamless Broadcast Flooring - System - Low-viscosity Binder For Trowel Applied Mortar - Flooring - High-quality Concrete Epoxy Primer - For Damp Surfaces - Topcoat: 2 Coats Of Non-skid Polyurethane Floor Coating - General Application: Measure The Floor Area To Be Painted And Buy Enough Paint For The Entire Project. Stir Well. Apply Liberally. Avoid Light Foot Traffic For The Next 24 Hours. Do Not Apply When Surface Or Air Temperature Is Below 20°c Or If Rain Is Expected Within 5 Hours. Apply Liberally With A 3/8” Nap Roller, But Avoid Excessive Brushing Or Spreading Too Thinly. Do Not Let Water Sit On The Painted Surfaces Before 14 Days To Ensure Proper Curing. • Floor Tile Works  Toilets And Janitor’s Closet – 30cmx30cm Non-skid Homogeneous Floor Tiles.  Cuttings On Both Ends Of The Walls Shall Be Of Equal Width With The Floor Finish.  All Exposed Corner Edges Shall Be Provided With Pvc Tile Trims.  No Human Traffic Or Construction Loads Shall Be Applied To All Newly Installed Tiles, And Allow Setting Mortar And Adhesive To Cure Prior. Ii. Wall & Ceiling Finishes • Wall Tile Works  All Toilets – 30cmx60cm Glossy/polished Ceramic Tiles.  Cuttings On Both Ends Of The Walls Shall Be Of Equal Width With The Floor Finish.  All Exposed Corner Edges Shall Be Provided With Pvc Tile Trims. - No Human Traffic Or Construction Loads Shall Be Applied To All Newly Installed Tiles, And Allow Setting Mortar And Adhesive To Cure Prior. • Painting Works  Paint Materials And Samples Swatches Shall Be Approved By The Architect.  Examine Substrate And Conditions Under Which Painting Will Be Performed. Proceed With The Work Only When Conditions Are Satisfactory.  Do Not Paint Over Dirt, Rust, Scale, Grease, Moisture, Scuffed Surfaces, Or Conditions Otherwise Detrimental To Formation Of A Durable Paint Film.  Clean Surfaces To Be Painted Before Applying Paint Or Surface Treatments. Remove Oil And Grease Prior To Mechanical Cleaning. Program Cleaning And Painting So That Contaminants From Cleaning Process Will Not Fall Into Wet, Newly-painted Surfaces.  Perform Preparation And Cleaning Procedures In Accordance With Paint Manufacturer’s Instructions And As Herein Specified, For Each Particular Substrate Condition.  Ferrous Metals: Clean Non-galvanized Ferrous-metal Surfaces That Have Not Been Shop Coated; Remove Mortar, Plaster, Grease, Dirt, Rust, Loose Mill Scale And Other Foreign Substances By Solvent Or Mechanical Cleaning Methods That Comply With The Recommendations Of The Steel Structures Painting Council, Before Priming Coat Is Applied. • Painting Systems  Exterior Surfaces: - Concrete, Concrete Masonry, Rendered Smooth - Concrete Neutralizer – One (1) Coat, Dry For 6 Hours. - Putty Surface Imperfections, Hairline Cracks With Patching Compound Using Putty Knife - Prime – Two (2) Coats Flat Latex, Dry For Two (2) Hours. - Topcoat – Two (2) Coats Of Semi-gloss Latex, Two (2) Hours Interval Between Coats. - Thinning / Clean-up Solvent – Water - Application – By Brush, Roller, Or Airless Spray  Interior Surfaces: - Concrete, Concrete Masonry, Rendered Smooth - Concrete Neutralizer – One (1) Coat, Dry For 6 Hours. - Putty Surface Imperfections, Hairline Cracks With Patching Compound Using Putty Knife. - Prime – Two (2) Coats Flat Latex, Dry For Two (2) Hours. - Topcoat – Two (2) Coats Of Semi-gloss Latex, Two (2) Hours Interval Between Coats. - Thinning / Clean-up Solvent – Water - Application – By Brush, Roller, Or Airless Spray  Ceiling & Drywall Surfaces: - Repair Surface Imperfections With Putty Using Putty Knife, Dry For 2 Hours And Sand. - Apply Mesh Tape On Board Joints And Seal Gaps With Patching Compound. Dry For Two (2) Hours And Sand. - Primer – Flat Latex, Dry For Two (2) Hours. - Topcoat – Two (2) Coats Of White Flat Latex Paint, Two (2) Hours Interval Between Coats. - Thinning / Clean-up Solvent - Water - Application – By Brush, Roller, Or Airless Spray  Cabinetries, Closets, Counters, Doorjambs And Doors: - Primer: One (1) Coat Of Lacquer Primer Surfacer - When Necessary, Putty Surface Imperfections, Hairline Cracks With Lacquer Spot Putty Using Putty Knife. Dry For 4 Hours And Sand. - Primer: One (1) Coat Of Lacquer Primer Surfacer - Topcoat – Two (2) Coats Of Automotive Lacquer Paint Finish, One (1) Hour Interval Between Coats. - Thinning / Clean-up Solvent – Lacquer Thinner - Application – By Airless Spray • Dry Walls & Interior Wall Claddings  Walls - Fiber Cement Board In 12.00mm X 1.2m X 2.4m  Fiber Cement Board Shall Be Stored In Elevated And Well Protected Area. Boards With Broken Edges, Lacerations Etc. Will Not Be Permitted To Be Installed.  Framing - 2”x4” 0.5mm Thick Metal Studs Spaced At 0.40m X 0.40m On Centers And 2”x4” 0.5mm Thick Metal Tracks. • Dry Ceiling  Ceiling - Fiber Cement Board In 4.50mm X 1.2m X 2.4m  Fiber Cement Board Shall Be Stored In Elevated And Well Protected Area. Boards With Broken Edges, Lacerations Etc. Will Not Be Permitted To Be Installed.  Framing - On 0.40mm Thick, 19mm X 50mm Double Furring, And 0.80mm Thick, 12mmx38mm Carrying Channel With Vertical Hanger, Spaced At 0.40m X 0.40m On Centers. • Rendering To Chb Or Concrete Surfaces  All Surfaces To Be Rendered Or Cement Plastered Shall Be Clean From Any Loose Material Or Contamination To Provide Strong Bond Between Plaster And The Surface.  Mix Proportion Shall Not Be Less Than 1 Part Of Cement To 4 Parts Of Screened Sand. Necessary Adjustments Shall Be Made To Provide A Strong And Consistent Mix, Free From Cracking Due To Rapid Hydration Of Plaster Mix.  Tampering Of Previously Mix Concrete Will Not Be Permitted.  All Surfaces To Receive Paint Finish Shall Be Smooth Whilst Surfaces To Receive Tiles Shall Be Rough To Provide Better Adhesion Or Bond. • Doors And Windows  Glass Door (glass/glazing) – 10mm Thk. Tempered Clear Glass On 50mm X 100mm Powder-coated Aluminum Framed Sliding Door With 2" X 6" Powder Coated Aluminum Jamb With Complete Hardware Accessories.  Glass Partitions (glass/glazing) – 6.00mm Thk. Clear Tempered Glass Fixed Glass On Powder-coated Aluminum Frame W/ Complete Hardware Accessories.  Windows (glass/glazing) – 6.00mm Thk. Clear Glass Awning Type Analok Aluminum Frame W/ Complete Hardware Accessories And Window Frame Weatherstripping.  All Metal Doors And Jambs – Hollow Core Metal Flush Type Swinging Door With 2" X 6" Steel Jamb – All In Paint Finish By Spray, W/ Complete Hardware And Door Accessories, Including Door & Jamb Seals As Indicated On Drawings, Completely Operational  All Doors And Jambs – Provide All Door Keys With Key Chains And Key Tags With Color And Specifications Subject For Approval Of The Healthcare Facility. • Specialties  Concrete Countertop Sink - Finish – Countertop Granite Slab, 0.60x2.40mm, Full Bullnose Edge On All Areas As Indicated On Drawings - Inclusions – Countertop Backsplash And Aprons At 0.10m - Thickness – 32mm - Finish And Color – As Selected By Healthcare Facility - Do Not Use Defective Pavers That Might Be Visible Or Cause Staining In Finished Work. - Cut Unit To Provide Pattern Indicated And In A Manner That Will Provide Clean, Sharp, Unchipped Edges.  Supply And Installation Of Built-in Cabinets And Shelves - Finish – As Indicated On Drawings - Work Includes But Is Not Limited To: - 3rd Floor Icu Nurse Station - 3rd Floor Icu-med Prep Room - 3rd Floor Nurse Station - 3rd Floor Nurse Station-med Prep Room - 3rd Floor Nurse Station-clean Linens Room - Miscellaneous  Building/room Signages/wayfinding Systems  Third Floor - Signages - Room Identification Sign (for Patient Rooms) - "isolation Room 17", 6mm Thick Frosted Acrylic - Room Identification Sign (for Patient Rooms) - "isolation Room 18", 6mm Thick Frosted Acrylic - Room Identification Sign (for Patient Rooms) - "isolation Room 19", 6mm Thick Frosted Acrylic - Room Identification Sign (for Patient Rooms) - "intensive Care Unit", 6mm Thick Frosted Acrylic - Area Identification (sticker Mounted) - "icu Unit 1/2/3", Frosted Sticker Mounted On Glass Surface - Room Identification Sign (for Service Rooms) - "dirty Utility", 6mm Thick Frosted Acrylic - Room Identification Sign (for Service Rooms) - "nurse Station", 6mm Thick Frosted Acrylic - Room Identification Sign (for Service Rooms) - "medicine Preparation Room", 6mm Thick Frosted Acrylic - Regulatory Sign With Room Label (authorized Personnel Only) – “electrical Room”, 6mm Thick Frosted Acrylic - Regulatory Special Signs (access Ramp Sign), 6mm Thick Frosted Acrylic - Restroom Identification – “all Gender Toilet”, 6mm Thick Frosted Acrylic - 3rd Floor - Emergency Exit Plan, 6mm Thick Frosted Acrylic - Way Finder Sign, 6mm Thick Frosted Acrylic - Smoke Free Building Sign, 6mm Thick Frosted Acrylic  Ground To Second Floor - Signages - 2nd Floor - Emergency Exit Plan, 6mm Thick Frosted Acrylic - 1st Floor - Emergency Exit Plan, 6mm Thick Frosted Acrylic  Supply And Installation Of Left Façade Enclosure - Work Includes But Is Not Limited To: - All Wall Areas As Indicated On Drawings (specifically On Left Façade)  Material Specification: - Fixed Framings In Paint Finish - Miscellaneous To Complete All Works G. Plumbing Works Provide All Labor, Materials And Equipment And Perform All The Work Necessary For The Complete Execution Of All The Work As Shown On Drawings And Specified In This Specification. Scope Of Works Shall Include But Does Not Be Limited To The Following Major Items Of Work: • Sanitary And Waterline Piping Works  Furnish And Install Complete Water Distribution System Including Incoming Supply Pipes And Connections, Pipes, Valves, Faucets, Accessories, Etc.  Storage, Delivery, Protection Before Installation And Connection Of Sanitary Line Accessories.  All Sanitary Pipes And Fittings To Be Used Shall Be Made Of Polyvinyl Chloride (pvc Pipes) Series 1000  All Waterline Pipes And Fittings To Be Used Shall Be Made Polypropylene Random Co-polymer (ppr Pipes)  Connections From Existing Water Supply And Existing Catch Basins.  Pressure Testing Of The Installed Water Distribution System.  Leakage Testing Of Soil, Waste, Vent, And Catch Basins And Septic Tank  Disinfections Of Water Distribution System.  Furnish And Install All Required Consumable Materials And Materials Tube Installed.  Investigation Of All Conflicts Of This Work And Coordination With Other Trades. • Plumbing Fixtures, Toilet & Sink Accessories * Submit Samples For Approval Prior To Installation" ** Faucets, Valves & Other Accessories Shall Be Japan, U.s., & E.u. Made  Two-piece Water Closet/s (push Button,4/6 Liters Water Saver) With Wall-mounted Semi-recessed Ceramic Tissue Holder, Wall-mounted Semi-recessed Ceramic Soap Holder, Complete Accessories  Wall Hung Lavatory W/ Complete Fittings & Accessories  Wall Hung Lavatory W/ Half-pedestal W/ Complete Fittings & Accessories  Stainless Steel 304 Lavatory Faucet  Stainless Steel 304 Two-way Faucet W/ Telephone Shower  50x45x20 Cm Stainless Steel 304 Single Bowl Surface Mounted Kitchen Sink W/ Complete Fittings & Accessories  Surface-mounted Long Neck Faucet For Kitchen Sink (med. Prep. Room)  Hand Bidet  Ss 304 Towel Bar  Stainless Steel Floor Drain, 6"x6" H. Electrical Works Provide All Labor, Materials And Equipment And Perform All The Work Necessary For The Complete Execution Of All The Work As Shown On Drawings And Specified In This Specification. Scope Of Works Shall Include But Does Not Be Limited To The Following Major Items Of Work: • Panel Boards And Circuit Breakers At 3rd Floor 3 Blower (exhaust & Supply Blower Panelboard) Assembled In Nema 1 Enclosure, Wall Mounted, Swing Dead Front, Powder Coated With Terminal Lugs In Crimping Type Ready, With Grounding Busbar Main: 60at,3p, 100af, 10 Kaic, 230 V, Mccb Branches: 4 - 30at/100af, 2p, 230 V, Mcb 2 - 20at/100af, 2p, 230 V, Mcb • Roughing-ins  20mm Dia.upvc Pipe  20mm Dia. Upvc Male Adapter With Locknut  25mm Dia.upvc Pipe  25mm Dia. Upvc Male Adapter With Locknut  20mm Corrugated Electrical Flexible Hose  20mm Electrical Flexible Hose Connector  Junction Box With Cover  Utility Box  Square Box  Consumables • Wires And Cables  Thhn/thwn Wire - 2.0mm², 3.5mm², 5.5mm², 14.0mm², 60.0mm² • Wiring Devices  Single Pole Switch With Led Indicator, Flush Type Modern Series  Duplex Switch With Led Indicator Flush Type Modern Series  Triplex Switch With Led Indicator Flush Type Modern Series  Three-way Switch Two Gang  Duplex Universal Convenience Outlet, 3 Prong Modern Series, 16a, 230v  Duplex Universal Outlet, Floor Mounted Type, 16a, 230v  Acu Outlet, Universal, 30a, 230v W/ Grounding-type • Lighting Fixtures  4"ø Downlight, With 11w Led Recessed Mounted  60 X 60 Square Type Recessed Led Panel  Emergency Light  Exit Light  30 Watts Led Flood Light I. Auxiliary Works To Include Fixing And Installation; Complete Accessories And Necessary Consumables; All In Accordance With Auxiliary Plan And Specification And As Indicated On Detailed Cost Estimates: • Fire Alarm And Detection System  Roughing-ins / Wires: - 15mmø Emt Pipe, Coupling, Connector - Pullbox - Metal Flexible Conduit 1/2" - Straight Connector 1/2" - Junction Box W/ Cover - Utility Box - Conduit Supports / Hangers - 1.25mm2 Twisted Pair - Consumables - Equipment: - Smoke Detector • Paging System  Roughing-ins / Wires: - 15mmø Upvc Pipe, Male Adapter With Locknut - Metal Flexible Conduit 1/2" - Straight Connector 1/2" - Junction Box With Cover - 1.25mm2 Twisted Pair - Consumables - Equipment: - Ceiling Speaker • Cctv System  Roughing-ins / Wires: - 15mmø Upvc Pipe - 15mm Dia. Upvc Male Adapter With Locknut - Junction Box With Cover - Utility Box With Cover - Utp Cat 6 4pairs - 1 Gang Outlet - Consumables  Equipment: - Ip Camera Dome Type J. Fire Protection Works To Include Fixing And Installation; Complete Accessories And Necessary Consumables; All In Accordance With Fire Protection Plan And Specification. • Black Iron Pipes, Fittings, Valves And Accessories: - Bi Pipes Schedule 40 @ 6m, Seamless (also Including Drain Pipe Riser And Auto Sprinkler Riser) And All Fittings, Valves And Accessories As Indicated On Detailed Cost Estimates • Sprinkler Heads And Accessories - Pendent Type: 135 Degrees To 165 Degrees - Sidewall Type: Standard Coverage • Others – Hangers And Supports, Miscellaneous And Consumables (including Painting And Tagging) • Testing And Commissioning – Configuration, Testing And Commissioning, Documentation, Training And Orientation K. Mechanical Works To Include Fixing And Installation; Complete Accessories And Necessary Consumables; All In Accordance With Mechanical Plan And Specification And As Indicated On Detailed Cost Estimates: • Air-conditioning Works - 3.0 Hp Split Type Aircon, Inverter Type, - 2.0 Hp Split Type Aircon, Inverter Type - 1.0 Hp Split Type Aircon, Inverter Type - Consumables • Ventilation Works - Bag/s In Bag/s Out Exhaust Blower Equipment - Panel Carbon Filter 16"x16"x2" - Hepa Filter With Aluminum Separator - Ducting L. Request For Final Inspection • Contractor Shall Submit Its Written Request For A Final Inspection Of The Project To The Medical Center Chief Office At Least Seven (7) Days Prior To Project Inspection & Turn-over. M. Tools And Equipment • Various Basic And Advanced Masonry/electrical/carpentry Tools • Measuring And Layout Tools • Waterproofing Application And Miscellaneous Tools • Safety Equipment • Utility Vehicle General Guidelines • All Construction Works Shall Be Undertaken By Contractor In Accordance With Existing Laws And All Other Applicable Rules And Regulations. • The Contractor Shall Be Responsible In Setting Out Reference Lines, Elevations (lines And Grades) Prior And During The Execution Of The Works. All References Shall Be Maintained And Protected By The Contractor At His Own Expense. Disturbed References Shall Be Restored To Its Original Position Without Extra Cost To Devmh. • The Contractor Shall Carry Out The Works Properly And In Accordance With This Contract. The Contractor Shall Provide All Supervision, Labor, Materials, Plant And Equipment, Which May Be Required. • The Contractor Shall Commence Execution Of The Works On The Start Date And Shall Carry Out The Works In Accordance With The Approved Pert/cpm Network Diagram Submitted By The Contractor, As Updated With The Approval Of The Procuring Entity’s Representative, And Shall Complete The Works By The Intended Completion Date. • The Contractor Shall Be Responsible For The Safety Of All Activities On The Site. • During On-going Construction And Before The Turn-over Of The Project, Engineering & Facilities Management Staff, End-users, Twg And Bac Shall Inspect The Works Undertaken By Contractor. Hospital Engineers And End-users Discover Any Deviations By Contractor From The Approved Construction Plans, Contractor Shall Be Required To Rectify All Such Deviations, Within Such Period Required By Client. • Contractor Shall Have Full Responsibility For Any And All Damages To Existing Hospital Facilities, Utilities, And/or Any Portion Of The Hospital’s Common Area, Due To The Works Undertaken By Contractor, Whether Accidental Or Intentional. • No Variation Order Shall Be Undertaken Unless Verified By Hospital Engineer And Approved By Executive Committee. • Contractor Shall Not Cover Or Block Stub-outs (cleanouts, Water Source, Exhaust, Sewer, Drainage, Etc.) When Not Utilized. Said Stub-outs Shall At All Times Be Free Of Obstructions And Easily Accessible. • Contractor Shall Secure A Utility Tapping Permit Prior To Tapping From Utility Provision. • Electricity And Water Consumed During Construction Shall Be Charged To Contractor. • End-users Reserves The Right To Inspect The Works At Any Time. • Contractor Shall Insure And Hold Client, Its Affiliates, Officers, Directors, Stockholders, Employees, Agents, And/or Representatives, Free And Harmless From And Against Any Injury, Losses, Claims, Damages, Liabilities, Expenses, And/or Costs Of Litigation, Resulting From Or Arising Out Of The Works Undertaken By Contractor. • In Event Of Force Majeure, The Contractor Shall Rectify, Replace Or Build The Unfinished Projects When It Is Not Yet Completed And Accepted W/o Additional Cost For The Procuring Entity. • Contractor Shall Comply With The Construction House Rules Of This Hospital. Time Of Completion • The Completion Of The Project Shall Be One-hundred Twenty (120) Calendar Days From The Date Of Effectivity.