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Details: Request For Information (rfi) Only metabolomics Analysis Services For Urine, Blood, Fecal, Saliva and Tissue Samples market Survey Request: this Is A Request For Information Only For Market Research And Planning Purposes Only, As Defined In Far 15.201(e). This Is Not A Solicitation Or Request For Competitive Proposals. Responses To This Notice Are Not Offers And Cannot Be Accepted By The Government To Form A Binding Contract. It Is Not To Be Construed As A Commitment By The Government Nor Will The Government Pay For The Information Solicited. No Solicitation Document Exists Or Is Guaranteed To Be Issued As A Result Of This Notice. Respondents Are Advised That The Government Is Under No Obligation To Acknowledge Receipt Of The Information Received Or Provide Feedback To Respondents With Respect To Any Information Submitted, And The Government Will Not Reimburse Respondents For Preparation Of The Response. Response To This Notice Is Strictly Voluntary And Will Not Affect Future Ability To Submit An Offer If A Solicitation Is Released. There Is No Bid Package Or Solicitation Document Associated With This Announcement. background: the United States Army Medical Research Institute Of Environmental Medicine – Military Nutrition Division (usariem – Mnd) Is Requiring Specialized Analytical Services Necessary To Provide Untargeted And Targeted Metabolomics Measurement In Human Biological Samples (urine, Blood, Feces, Saliva, And Tissue) And Data Analysis For On-going Research Studies Led By Usariem Primary Investigators (pi’s). requirement: usariem – Mnd Is Requiring The Measurement Of Multiple Biochemical Markers Of Metabolic, Nutritional, And Physiologic Status And Function, Known As Metabolites, In A Variety Of Biological Matrices. This Will Require Untargeted Metabolomics Analysis (i.e., Measurement Of Hundreds-to-thousands Of Metabolites In Single Biological Samples) And Targeted Metabolomics Analysis (i.e., Quantitative Measurement Of Specific Metabolites) In Both Planned And Future Research Studies. The Services Include, But Are Not Limited To: laboratory Analysis Services: laboratory Analysis Services Must Include The Following, At Minimum: 1. Must Have Ultra-high Performance Liquid Chromatography-tandem-mass Spectrometry (uplc-ms/ms) With A Heated Electrospray Ionization Source And Orbitrap Mass Analyzer Capability That Can Be Operated In Both Positive And Negative Ion Modes, And Gas Chromatography-mass Spectrometry (gc-ms) Capability For Measuring Metabolites Derived From Multiple Biochemical Pathways In Human Blood, Urine, Saliva, Stool, And Muscle. 2. Must Have The Capability To Detect At Least 8,000 Novel Metabolites And To Validate And Confidently Identify At Least 5,000 Known Metabolites Using Company-owned Libraries. 3. Must Use Bioinformatics Systems That Include A Laboratory Information System (lims) That Enables Fully Auditable Laboratory Automation Through A Secure, Easy To Use, And Highly Specialized System. This System Must At Least Include Sample Accessioning, Sample Preparation, Instrumental Analysis And Reporting, And Must Also Be Able To Provide Advanced Data Analysis. The System Must Enable Data Extraction And Peak Identification, Utilize Data Processing Tools For Quality Control And Compound Identification In Accordance With Good Laboratory Practices (glp), And Contain, At A Minimum, A Collection Of Information Interpretation And Visualization Tools Used Specifically For Metabolomics Data Analysis. 4. Potential Offeror’s Must Show Detailed Expertise In Bioinformatics Analysis Of Metabolomics Data, Ability To Provide User-friendly Web Portals For Exploring, Analyzing, And Visualizing Metabolomics And Electronic Reports Summarizing Analytical Results And Their Interpretation. 5. Contractor Staff Must Include Phd-level Scientists Available To Assist Usariem Scientists In Interpretation Of Study Results Such As Analyzing, Summarizing, And Interpreting The Generated Untargeted And/or Targeted Metabolomics Data For All Samples. Contracting Company And/or Its Scientists Must Show History Of Contributing To Peer-reviewed Publications Using The Above-mentioned Technologies. 6. Must Have The Capability To Conduct Quantification Of Short-chain Fatty Acids And Bile Acids And Their Derivatives In Multiple Biological Sample Types. 7. Must Have Laboratory Systems Governed By Standard Operating Procedures (sop’s) That Are Reviewed And Updated With Adherence To Good Clinical Laboratory Practice (glp) Standards And Quality Control For All Analysis Conducted. 8. Laboratory Technicians Trained On Appropriate Measurement Procedures And Validated Equipment. data Analysis Services: data Analysis Services Must Include The Following, At Minimum: 1. Must Be Able To Provide A List Of Biochemicals Detected And Identified By Biochemical Name, Biochemical Class (grouped By Super Pathway And Sub Pathway), Platform Used For Measurement, Kegg Identifier, Hmdb Identifier, Pubchem Identifier, Chemspider Identifier And Cas Identifier. 2. Must Include Kegg/hmbd Links For All Compounds Having A Kegg Or Hmdb Id. 3. Must Be Able To Show Relative Quantitation Expressed As Peak Area (both Raw And Normalized With And Without Missing Data Imputed). 4. Must Deliver Results Of All Statistical Analyses Requested By The Primary Investigator (p.i.) Including Unadjusted P-values And False Discovery Rate Adjusted P-values (q-value). 5. Must Be Able To Provide Box Maps Showing Quantification Of All Detected Compounds By Study Group And Timepoint. 6. Must Be Able To Provide A Narrative Summary Of All Results Along With Their Interpretation Within The Context Of The Study Design. Narrative Summary Will Include Visualizations, Demonstrating Results Of Statistical Analyses And Biochemical Pathways, And Methods Sufficiently Detailed To Be Used In Peer- Reviewed Publications. 7. Must Provide Access To A Web-based Portal In Which The Usariem Pi Can Continue To Access, Analyze, And Visualize The Generated Metabolomics Data Using Data Analysis Tools Including Principal Components Analysis, Partial Least Squares Discriminant Analysis, Volcano Plots, Hierarchical Clustering, T-tests, And Anova. additional Comments For Analytical Support Under This Effort: 1. Interested Parties Who Wish To Respond Must Have A Bioinformatics System Consisting Of A Laboratory Information Management System (lims) That Enables Fully Auditable Laboratory Automation Through A Highly Specialized System, Access To A Specialized Library Of Purified Standards Or Recurrent Unknown Entities And Provide Usariem Scientists Access To Visualization And Interpretation Software To Conduct Analysis For This Requirement. Previous And Ongoing Studies At The Usariem Have Been Performed Under These Systems And Future Analyses Must Utilize The Same Methods And Equipment To Allow For Valid And Accurate Comparisons Across Studies. submittals: summaries Of The Services As Listed Above Shall Be No More Than Ten (10) Pages In Length (1 Side Of 1 Sheet Of Paper Counts As A “page”) And Shall Describe Service Capabilities In Each Of These Areas. interested Parties Shall Provide Their Business Size Status Based Upon Naics Code 541380, Testing Laboratories And Services, With A Small Business Size Standard Of $19m, And Their Cage Code As Registered At Sam.gov. Interested Parties May Include Brochure Information (if Appropriate) With The Summary Package By The Government's Requested Date Of Submittal Of 07 January 2025. Interested Parties Shall Submit Information In Response To This Rfi To: Kasey.l.carroll.civ@health.mil. responses Shall Be Submitted And Received Via Email No Later Than Two O’clock Post Meridian Eastern Standard Time (2:00pm Est) Tuesday 07 January 2025. Documents Shall Be Electronic In Microsoft Word, Excel, Power Point, And/or Adobe Portable Document Format (pdf) And Provided As Attachments To The Email. No Telephonic Responses To This Rfi Will Be Considered. questions Concerning This Request For Information (rfi) May Be Addressed By Contacting: Kasey.l.carroll.civ@health.mil. All Information Received In Response To This Rfi That Is Marked Proprietary Will Be Handled Accordingly. Responses To This Rfi Are Not Offers For A Contract And Will Not Be Used By The Government To Form A Binding Contract. Responders Are Solely Responsible For All Expenses Associated With Responding To This Rfi. Vendors Having The Services That They Believe Would Be Suitable For Operations As Described Herein Shall Submit All Supporting Documentation Requested By This Rfi To The Point Of Contact (poc) Noted Above. please Provide Information On Your Organization In The Following Areas: company Name, Address And Single Point Of Contact With Name, Title, Telephone Number And E-mail Address. duns Number And Cage Code confirmation Of Current Active Registration In System For Award Management (sam) primary Naics Code(s) And Business Size (i.e., Small/large) gsa Schedule, If Available commercial Price List, If Gsa Schedule Is Not Available product Specific Brochures Literature provisions And Clauses: 52.215-3 Request For Information Or Solicitation For Planning Purposes. request For Information For Planning Purposes (oct 1997) (a) The Government Does Not Intend To Award A Contract On The Basis Of This Solicitation Or To Otherwise Pay For The Information Solicited Except As An Allowable Cost Under Other Contracts As Provided In Subsection 31.205-18, Bid And Proposal Costs, Of The Federal Acquisition Regulation. (b) Although "proposal" And "offeror" Are Used In This Request For Information, Your Response Will Be Treated As Information Only. It Shall Not Be Used As A Proposal. (c) This Request For Information (rfi) Is Issued For The Purpose Of Specialized Analytical Services Necessary To Provide Untargeted And Targeted Metabolomics Measurement In Human Biological Samples. (end Of Provision)

Details: Description Request For Quotation Date: February 4, 2025 Rfq No.: 2025-10 Name Of Company: ____________________________________________________________________ Office Address: _______________________________________________________________________ Business Permit No.: _____________________ Valid Until: ______________________________ Tax Id No.: __________________________________________________________________________ Philgeps Reg. No. (required): __________________________________________________________ The Talavera General Hospital, Through Its Bids And Awards Committee (bac), Intends To Apply The Sum Eighty Thousand Pesos (php 80,000.00) Being The Approved Budget For The Contract (abc) From Regular Fund For Payments Under The Contract Iso 9001:2015 1st Surveillance Audit Through Small Value Procurement Under Sec. 53.9 Of The Republic Act. 9184. Please Submit Your Duly Signed Quotation Addressed To The Bids And Awards Committee (bac) Chairperson And To The Given Address Below, On Or Before February 10, 2025, Monday, 5:00pm, Subject To The Compliance With The Terms And Conditions Provided On This Request For Quotation (rfq): Dhonna Sheila A. Baterina, Md, Mha, Fpogs Chairperson, Bids And Awards Committee Talavera General Hospital Maestrang Kikay District, Talavera, Nueva Ecija Tel. No. (044) 940 – 7136 Loc 170 – 171 Email Address: Procurement.tgh@gmail.com Standard Requirements: Document Remarks Mayor’s Permit Or Business Permit Please Submit Your Valid Mayor’s Permit Or Business Permit. Failure To Provide The Required Document Will Result In The Automatic Disqualification Of Your Quotation. Notarized Omnibus Sworn Statement (gppb-prescribed Form) If Unable To Have The Document Notarized, You May Submit A Signed Unnotarized Omnibus Sworn Statement (in The Prescribed Template), Subject To Compliance Therewith After Award Of Contract But Before Payment. Updated Company Profile Submit An Updated Company Profile Together With This Request For Quotation. Certifying Body’s Documentary Requirements •list Of Auditors To Comprise The Audit Team, Technical Experts With Their Respective Curriculum Vitae And Auditor Authorization Certificates; •notarized Certificate Attesting The Appointment Of The Participating Service Provider’s Representative/authorized Signatory. For Any Clarification, Or Further Information You May Refer To: Liwayway Dg. Pangilinan Administrative Officer V/head Bac Secretary Talavera General Hospital Procurement Office Maestrang Kikay, Maharlika Hi-way, Talavera, Nueva Ecija Telefax: [044] 940-7136 Loc. 170 To 171 Email: Procurement.tgh@gmail.com Note: 1. If A Revised Philgeps Certificate Of Platinum Registration And Membership Is Submitted You Can Disregard The Standard Requirement No. 1 (mayor’s Permit Or Business Permit). _____________¬_______________ Dhonna Sheila A. Baterina, Md, Mha, Fpogs Chairperson, Bids And Awards Committee Philgeps: February 5, 2025 Instructions: Note: Failure To Follow These Instructions Will Disqualify Your Entire Quotation. I. Do Not Alter The Contents Of This Form In Any Way. Ii. The Use Of This Rfq Is Mandatory. In Case Of Any Changes Or Alteration, The Submitted Quotation Shall Be Automatically Rejected. If Another Form Is Used Other Than The Latest Rfq, The Quotation, The Submitted Quotation Shall Be Automatically Rejected. Iii. All Mandatory Technical Specifications Must Be Complied With. Failure To Comply With The Mandatory Requirements Shall Render The Quotation Ineligible/disqualified. Iv. Quotations May Be Submitted Through Electronic Mail At Procurement.tgh@gmail.com. V. Quotations, Including Documentary Requirements, Received After The Deadline Shall Not Be Accepted. For Quotations Submitted Via Electronic Mail, The Date And Time Of Receipt Indicated In The E-mail Shall Be Considered. Terms And Conditions: I. Bidders Shall Provide Correct And Accurate Information Required In This Form. Ii. Any Interlineations, Erasures, Or Overwriting Shall Be Valid Only If They Are Signed Or Initialed By You Or Any Of Your Duly Authorized Representative/s. Iii. Price Quotation/s Of The Winning Bidder Will Be Contracting Price/amount Which Is Considered Fixed Price. Iv. Price Quotation/s, To Be Denominated In Philippine Peso, Shall Include All Taxes, Duties, And/or Levies Payable. V. Quotations Exceeding The Approved Budget For The Contract Shall Be Rejected. Vi. In Case Of Two Or More Bidders Are Determined To Have Submitted The Lowest Calculated Quotation/lowest Calculated And Responsive Quotation, The Talavera General Hospital Shall Adopt And Employ “draw Lots/toss Coin” As The Tie-breaking Method To Finally Determine The Single Winning Provider In Accordance With Gppb Circular 06-2005. Vii. Award Of Contract Shall Be Made To The Lowest Quotation Which Complies With The Terms Of Reference, Requirements And Other Terms And Conditions Stated Herein. Viii. The Item/s Shall Be Delivered According To The Accepted Offer Of The Bidder. Ix. The Procuring Entity May Cancel Or Terminate The Contract At Any Time In Accordance With The Grounds Provided Under Ra No. 9184 And Its 2016 Revised Irr. X. The Rfq, Purchase Order (po)/job Order (jo), And Other Related Documents For The Above-stated Procurement Projects Shall Be Deemed To Form Part Of The Contract. Xi. This Project Will Be Awarded By Lot Which Will Be Evaluated Per Lot Item And The Award Will Be Given To The Lowest Calculated And Responsive Quotation. After Having Carefully Read And Accepted The Instructions And Terms And Conditions, I/we Submit Our Quotation/s For The Item/s As Follows: Technical Specifications # Description Quantity Unit Statement Of Compliance (“comply” Or “not Comply”) Note: Non-compliance With The Minimum Required Specifications Shall Be Rejected. 1 Iso 9001:2015 1st Surveillance Audit • Surveillance Audit Including Pre-audit Planning, Onsite Audit Time, Report Preparation, Cpg Administration Plus The Issue And Use Of The Cpg Certification Mark/ongoing Maintenance Of Cpg Registration • Reporting 1 Package Delivery Requirements - Delivery Within The Actual Date Of The Activities Terms Of Reference (tor) I. Tittle: Iso 9001:2015 1st Surveillance Audit Ii. Type Of Service: Hiring Of Iso Certifying Body For The Talavera General Hospital Iso 9001:2015 1st Surveillance Audit The Certifying Body Should Have The Following Qualifications: • The Certifying Body Must Have Assisted At Least Five (5) Doh Hospital For Iso 9001:2015 Certification; • The Certifying Body Must Have At Least Five (5) Years Iso 9001:2015 Auditing Experience; • The Certifying Body Must Have A Good Track Record Of Certifying Government Agencies For Quality Management. • The Auditor(s) Shall Have A Minimum Of Three (3) Years Iso 9001:2015 Auditing Experience And Have Medical Background And Expertise. The Certifying Body Should Submit The Following Documentary Requirements: • List Of Auditors To Comprise The Audit Team, Technical Experts With Their Respective Curriculum Vitae And Auditor Authorization Certificates; • Notarized Certificate Attesting The Appointment Of The Participating Service Provider’s Representative/authorized Signatory. Iii. Client: Talavera General Hospital Iv. Scope Of Certification: Provision Of Departmentalized Medical Service (pediatric, Internal Medicine, Obstetrics And Gynecology, Surgery, Anesthesia); In-patient/out Patient And Emergency Medical Care; Diagnostic Services (radiology And Clinical Laboratory); Nursing Care Services; Provision Of Pharmacological Supplies And Services Under Hospital Operation And Patient Support Including Ambulance Services. V. Duration Of Engagement, Timeline And Activities: Date Of Activity: February 21,2025 Year 2 – 2025: 1st Surveillance Audit Iso 9001:2015 Phase Activity Man Days 1 Surveillance Audit Including Pre-audit Planning, On-site Audit Time, Report Preparation, Cpg Administration Plus The Issue And Use Of The Cpg Certification Mark / Ongoing Maintenance Of Cpg Registration. 3.0 3 Reporting 1.0 Vi. Contract Price A. The Total Cost For The Complete Certifying Body Audit Shall Be Eighty Thousand Pesos (php 80,000.00) From Regular Fund For Payments Under The Contract Iso 9001:2015 1st Surveillance Audit. Year 2 – 2025: 1st Surveillance Audit Iso 9001:2015 Activity Abc • Surveillance Audit Including Pre-audit Planning, Onsite Audit Time, Report Preparation, Cpg Administration Plus The Issue And Use Of The Cpg Certification Mark / Ongoing Maintenance Of Cpg Registration. • Reporting 80,000.00 Financial Offer: Terms Of Payment: Payment Shall Be Made Within Fifteen (15) Days Upon Completion Of The Project/delivery And Submission Of Billing/invoice And User Acceptance Of The Product. Please Quote Your Best Offer For The Item/s Below. Please Do Not Leave Any Blank Items. Bid Price Form # Items Quantity Unit Abc Per Line Item Unit Cost Total Cost 1 Iso 9001:2015 1st Surveillance Audit 1 Package 80,000.00 Grand Total Name Of Representative Of The Bidder Address Tel. No.: Name Of Company Date

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